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PML 抗体

(Promyelocytic Leukemia (PML))
The protein encoded by this gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. This phosphoprotein localizes to nuclear bodies where it functions as a transcription factor and tumor suppressor. Its expression is cell-cycle related and it regulates the p53 response to oncogenic signals. The gene is often involved in the translocation with the retinoic acid receptor alpha gene associated with acute promyelocytic leukemia (APL). Extensive alternative splicing of this gene results in several variations of the protein's central and C-terminal regions\; all variants encode the same N-terminus. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008].
PML 抗体  (AA 411-510) PML 抗体  (AA 411-510) PML 抗体 (AA 411-510) (ABIN562289)

PML 适用: 人 WB, IF, ELISA, PLA 宿主: 小鼠 Monoclonal 1D12 unconjugated

PML 抗体  (N-Term) PML 抗体  (N-Term) PML 抗体 (N-Term) (ABIN6264315)

PML 适用: 人, 小鼠, 大鼠 WB, IHC, IF, ELISA, ICC 宿主: 兔 Polyclonal unconjugated

PML 抗体  (Sumoylation Site) PML 抗体  (Sumoylation Site) PML 抗体 (Sumoylation Site) (ABIN3032330)

PML 适用: 人 WB, IHC, IF, ELISA, FACS 宿主: 兔 Polyclonal unconjugated

PML 抗体 by 适用

Find PML 抗体 for a variety of species such as anti-Human PML, anti-Mouse PML, anti-Rat PML. The species listed below are among those available. Click on a link to go to the corresponding products.

PML 抗体 by 应用范围

Find PML 抗体 validated for a specific application such as WB, IHC, IF, ELISA. Some of the available applications are listed below. Click on a link to go to the corresponding products.

PML 抗体 by 抗体来源

Find PML 抗体 with a specific 抗体来源. The 抗体来源 listed below are among those available. Click on a link to go to the corresponding products.

PML 抗体 by 抗原表位

Find PML 抗体 with a specific epitope. The epitopes listed below are among those available. Click on a link to go to the corresponding products.

PML 抗体 by 克隆形成能力

Find available monoclonal or polyclonal PML 抗体. Click on a link to go to the corresponding products.

PML 抗体 by 克隆

Find PML 抗体 with a specific 克隆. The 克隆 listed below are among those available. Click on a link to go to the corresponding products.

PML 抗体 by 标记

Find PML 抗体 with a specific conjugate such as Biotin, FITC, APC. The conjugates listed below are among those available. Click on a link to go to the corresponding products.

Popular PML 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, IF, ELISA, PLA
Validations
  • (6)
Cat. No. ABIN562289
Quantity 100 μg
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application WB, IHC, IF, ELISA, ICC
Validations
  • (1)
  • (4)
Cat. No. ABIN6264315
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, IHC, IF, ELISA, FACS
Validations
  • (6)
Cat. No. ABIN3032330
Quantity 0.4 mL
Datasheet Datasheet
Reactivity Human
Application WB, IHC
Validations
  • (1)
  • (3)
Cat. No. ABIN3021659
Quantity 100 μL
Datasheet Datasheet
Reactivity Cow, Dog, Guinea Pig, Horse, Human, Mouse, Pig, Rabbit, Rat
Application WB, IHC
Validations
  • (5)
Cat. No. ABIN2777721
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, IF, ELISA
Validations
  • (3)
Cat. No. ABIN518988
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB, IF, IHC (p), FACS
Validations
  • (4)
Cat. No. ABIN389073
Quantity 400 μL
Datasheet Datasheet
Reactivity Human
Application WB, IHC, IF, ELISA
Validations
  • (2)
Cat. No. ABIN7188963
Quantity 100 μg
Datasheet Datasheet
Reactivity Cow, Guinea Pig, Horse, Human, Mouse, Rat
Application WB, IHC, IHC (p)
Validations
  • (2)
Cat. No. ABIN6741549
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, IHC, ICC
Validations
  • (3)
Cat. No. ABIN1175605
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, IHC, IF, ELISA
Validations
  • (3)
Cat. No. ABIN1533381
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB, IHC, IF, IC
Validations
  • (3)
Cat. No. ABIN7296622
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB
Validations
  • (1)
Cat. No. ABIN6242530
Quantity 50 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA
Validations
  • (1)
Cat. No. ABIN562288
Quantity 50 μL
Datasheet Datasheet
Reactivity Human
Application WB
Validations
  • (1)
Cat. No. ABIN6742751
Quantity 100 μL
Datasheet Datasheet

Latest Publications for our PML 抗体

Chen, Ou Yang, Juang, Chen, Chen, Tsui, Chang, Tsai, Hsueh, Liao: "Proteomic characterization of arsenic and cadmium exposure in bladder cells." in: Rapid communications in mass spectrometry : RCM, (2019) (PubMed).

Wu, Shao, Zhou, Sun, Wang, Yan, Liu, Wu, Ye, Huang, Zhou et al.: "Autophagy and Ubiquitin-Mediated Proteolytic Degradation of PML/Rarα Fusion Protein in Matrine-Induced Differentiation Sensitivity Recovery of ATRA-Resistant APL (NB4-LR1) Cells: in Vitro and in Vivo ..." in: Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, Vol. 48, Issue 6, pp. 2286-2301, (2018) (PubMed).

Li, Zhong, Liu, Yu, Chen, Wang, Shi, Yuan: "Evidence for Kaposi Sarcoma Originating from Mesenchymal Stem Cell through KSHV-induced Mesenchymal-to-Endothelial Transition." in: Cancer research, Vol. 78, Issue 1, pp. 230-245, (2018) (PubMed).

Lång, Eriksson, Schink, Lång, Blicher, Połeć, Brech, Dalhus, Bøe: "Visualization of PML nuclear import complexes reveals FG-repeat nucleoporins at cargo retrieval sites." in: Nucleus (Austin, Tex.), Vol. 8, Issue 4, pp. 404-420, (2018) (PubMed).

Niu, Livingston, Li, Beran, Daffis, Ramakrishnan, Burdette, Peiser, Salas, Ramos, Yu, Cheng, Strubin, Delaney Iv, Fletcher: "The Smc5/6 Complex Restricts HBV when Localized to ND10 without Inducing an Innate Immune Response and Is Counteracted by the HBV X Protein Shortly after Infection." in: PLoS ONE, Vol. 12, Issue 1, pp. e0169648, (2017) (PubMed).

Berscheminski, Brun, Speiseder, Wimmer, Ip, Terzic, Dobner, Schreiner: "Sp100A is a tumor suppressor that activates p53-dependent transcription and counteracts E1A/E1B-55K-mediated transformation." in: Oncogene, Vol. 35, Issue 24, pp. 3178-89, (2016) (PubMed).

Komatsu, Nagata, Wodrich: "An Adenovirus DNA Replication Factor, but Not Incoming Genome Complexes, Targets PML Nuclear Bodies." in: Journal of virology, Vol. 90, Issue 3, pp. 1657-67, (2016) (PubMed).

Yao, Wu, Chen, Zhang, Chen, Zhang: "The Arginine/Lysine-Rich Element within the DNA-Binding Domain Is Essential for Nuclear Localization and Function of the Intracellular Pathogen Resistance 1." in: PLoS ONE, Vol. 11, Issue 9, pp. e0162832, (2016) (PubMed).

Wimmer, Berscheminski, Blanchette, Groitl, Branton, Hay, Dobner, Schreiner: "PML isoforms IV and V contribute to adenovirus-mediated oncogenic transformation by functionally inhibiting the tumor-suppressor p53." in: Oncogene, Vol. 35, Issue 1, pp. 69-82, (2016) (PubMed).

Chen, Hu, Chen, Lin, Liu, Lin, Lang, Yen, Chen: "KLHL39 suppresses colon cancer metastasis by blocking KLHL20-mediated PML and DAPK ubiquitination." in: Oncogene, Vol. 34, Issue 40, pp. 5141-51, (2015) (PubMed).

Aliases for PML 抗体

promyelocytic leukemia (PML) 抗体
promyelocytic leukemia (Pml) 抗体
1200009E24Rik 抗体
AI661194 抗体
MYL 抗体
PML 抗体
PP8675 抗体
RGD1562602 抗体
RNF71 抗体
TRIM19 抗体
Trim19 抗体
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