Sepiapterin Reductase 蛋白 (SPR)产品概述

Full name:
Sepiapterin Reductase 蛋白 (SPR)
在www.antibodies-online.cn可供18 Sepiapterin Reductase (SPR) 蛋白的8不同的供货商。 再加上,我们可以发Sepiapterin Reductase 抗体 (99)Sepiapterin Reductase 试剂盒 (9)和数多这个蛋白质的别的产品。 总共135 Sepiapterin Reductase产品已列进来了。
AA409688, CG12117, DDBDRAFT_0188686, DDBDRAFT_0191275, DDB_0188686, DDB_0191275, Dmel\\CG12117, ENSMUSG00000071345, Gm10328, NK1R, NKIR, SDR38C1, SPR, sptr, SR, Tac1r, xspr
列出全部蛋白 基因 基因ID UniProt
SPR 20751  
SPR 29270 P18297
SPR 6697 P35270


按照种类Sepiapterin Reductase 蛋白 (SPR)


引用最多的Sepiapterin Reductase 蛋白

  1. Human SPR Protein expressed in Escherichia coli (E. coli) - ABIN666753 : Ohye, Hori, Katoh, Nagatsu, Ichinose: Genomic organization and chromosomal localization of the human sepiapterin reductase gene. in Biochemical and biophysical research communications 1998 (PubMed)
    Show all 2 references for 666753

更多Sepiapterin Reductase互动伙伴

Mouse (Murine) Sepiapterin Reductase (SPR) interaction partners

  1. SPR-mediated reduction of sepiapterin and redox cycling occur by distinct mechanisms

  2. biopterin contents in the brains of these knock-out mice were moderately decreased from postnatal day 0 (P0) and remained constant up to P21

  3. These data suggest an essential role of SPR in the biosynthesis of BH4, and that the SPR gene could be a candidate gene for PARK3.

Human Sepiapterin Reductase (SPR) interaction partners

  1. Expression substance P/neurokinin A (显示 TAC1 蛋白)/hemokinin-1 and their preferred neurokinin 1/neurokinin 2 (显示 TAC1 蛋白) receptors are dysregulated in uterine leiomyomata.

  2. results suggest that ARRB1 (显示 ARRB1 蛋白) plays an essential role in NK1R (显示 TACR1 蛋白)-mediated cell proliferation and G2/M transition in glioblastoma cells. Interference with ARRB1 (显示 ARRB1 蛋白)-mediated signaling via NK1R (显示 TACR1 蛋白) may have potential significance for therapeutic strategies targeting glioblastoma.

  3. The allele frequencies for the SPR c.596-2A > G (0.7%) polymorphism is not a major cause of Parkinson's disease in the Maltese.

  4. Data suggest that endogenous tachykinin ligands for neurokinin-1 receptor exhibit large variations in binding/activation kinetics; substance P (显示 TAC1 蛋白) exhibits fast association kinetics; neurokinin A (显示 TAC1 蛋白) exhibits slow association kinetics.

  5. We showed that pretreating a cardiomyocyte cell line (H9C2) and a TNBC cell line (MDA-MB 231) with aprepitant, a SP receptor antagonist that is routinely used to treat chemotherapy-associated nausea, decreased DOX-induced reduction of viability, apoptotic cell death, and ROS (显示 ROS1 蛋白) production in cardiomyocytes

  6. These findings reveal important insight into the molecular mechanisms of the NK1R (显示 TACR1 蛋白) complex as a critical component in a model of pediatric liver cancer and may support the development of novel therapeutic interventions for hepatoblastoma

  7. Neuropeptide signaling through neurokinin-1 (显示 TAC1 蛋白) and neurokinin-2 (显示 TAC1 蛋白) receptors augments antigen presentation by human dendritic cells

  8. Inhibition of CaV2.3 (显示 CACNA1E 蛋白) channels by NK1 (显示 CD160 蛋白) receptors is sensitive to membrane cholesterol but insensitive to caveolin-1 (显示 CAV1 蛋白).

  9. We earlier presented evidence for a physical interaction between ODC (显示 ODC1 蛋白) and SPR and we showed that RNAi-mediated knockdown of SPR expression significantly reduced native ODC (显示 ODC1 蛋白) enzyme activity and impeded Neuroblastoma (显示 ARHGEF16 蛋白) cell proliferation.

  10. NK-1 (显示 CD160 蛋白) activation could enhance EGFR (显示 EGFR 蛋白) expression and phosphorylation, and then activate EGFR (显示 EGFR 蛋白) related Erk/MAPK (显示 MAPK1 蛋白) and Akt (显示 AKT1 蛋白) pathway.

Cow (Bovine) Sepiapterin Reductase (SPR) interaction partners

  1. this study demonstrates an important role of endothelial SPR in modulating tetrahydrobiopterin and nitric oxide bioavailability

蛋白简介Sepiapterin Reductase (SPR)


This gene belongs to a gene family of tachykinin receptors. These tachykinin receptors are characterized by interactions with G proteins and contain seven hydrophobic transmembrane regions. This gene encodes the receptor for the tachykinin substance P, also referred to as neurokinin 1. The encoded protein is also involved in the mediation of phosphatidylinositol metabolism of substance P.

Alternative names and synonyms associated with Sepiapterin Reductase (SPR)

  • Sepiapterin reductase (Sptr)
  • sepiapterin reductase (sprE)
  • sepiapterin reductase (CpipJ_CPIJ000511)
  • sepiapterin reductase (sr)
  • sepiapterin reductase (7,8-dihydrobiopterin:NADP+ oxidoreductase) (spr)
  • Sepiapterin reductase (spre)
  • sepiapterin reductase (Spr)
  • sepiapterin reductase (spre)
  • sepiapterin reductase (7,8-dihydrobiopterin:NADP+ oxidoreductase) (Spr)
  • sepiapterin reductase (7,8-dihydrobiopterin:NADP+ oxidoreductase) (SPR)
  • tachykinin receptor 1 (TACR1)
  • tachykinin receptor 1 (Tacr1)
  • AA409688 蛋白
  • CG12117 蛋白
  • DDBDRAFT_0188686 蛋白
  • DDBDRAFT_0191275 蛋白
  • DDB_0188686 蛋白
  • DDB_0191275 蛋白
  • Dmel\\CG12117 蛋白
  • ENSMUSG00000071345 蛋白
  • Gm10328 蛋白
  • NK1R 蛋白
  • NKIR 蛋白
  • SDR38C1 蛋白
  • SPR 蛋白
  • sptr 蛋白
  • SR 蛋白
  • Tac1r 蛋白
  • xspr 蛋白

Protein level used designations for Sepiapterin Reductase 蛋白 (SPR)

sepiapterin reductase , CG12117-PA , Sptr-PA , Sepiapterin reductase , short chain dehydrogenase/reductase family 38C, member 1 , 7,8-dihydrobiopterin:NADP+ oxidoreductase , NK-1 receptor , NK-1R , substance-P receptor , tachykinin receptor 1 (substance P receptor; neurokinin-1 receptor) , SPR , neurokinin 1 receptor , substance p receptor

31781 Drosophila melanogaster
1793292 Rhodopirellula baltica SH 1
6031370 Culex quinquefasciatus
8627440 Dictyostelium discoideum AX4
100145068 Xenopus (Silurana) tropicalis
100195245 Salmo salar
100379197 Bombyx mori
100528817 Ictalurus punctatus
20751 Mus musculus
29270 Rattus norvegicus
6697 Homo sapiens
533836 Bos taurus
380273 Xenopus laevis
6869 Homo sapiens
24807 Rattus norvegicus
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