Cytochrome B-245, alpha Polypeptide (CYBA) ELISA试剂盒产品概述

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Cytochrome B-245, alpha Polypeptide ELISA试剂盒 (CYBA)
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别名:
b558, CYBA, MGC80750, nmf333, P22-PHOX, p22phox, zgc:66077
list all ELISA KIts 基因 基因ID UniProt
 CYBA CYBA 1535 P13498
小鼠 CYBA CYBA 13057 Q61462
大鼠 CYBA CYBA 79129 Q62737

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适于 Cytochrome B-245, alpha Polypeptide 相互作用对的更多 ELISA 试剂盒

Human Cytochrome B-245, alpha Polypeptide (CYBA) interaction partners

  1. PI3K (显示 PIK3CA ELISA试剂盒)/AKT (显示 AKT1 ELISA试剂盒) signaling only occurs when FLT3 (显示 FLT3 ELISA试剂盒)-ITD is expressed at the plasma membrane and is required for the production of NOX-generated ROS (显示 ROS1 ELISA试剂盒). ER retention of FLT3 (显示 FLT3 ELISA试剂盒)-ITD resulted in NOX4 (显示 NOX4 ELISA试剂盒) deglycosylation and p22(phox) protein degradation.

  2. CYBA gene ()49A>G polymorphism modifies the risk of coronary artery disease

  3. The study demonstrated that the genetic variants of rs9932581 and rs1049255 in CYBA might not be associated with preeclampsia.

  4. p22phox C242T polymorphism has a possible role in changing the genetic susceptibility to late-onset AD in ApoE 4 carriers of northern Han Chinese origin.

  5. CYBA mutations lead to one of the autosomal recessive forms of chronic granulomatous disease (AR220CGD) clinically characterized by recurrent and severe infections in early chilA large number of genetic variations of CYBA have been reported, among them the C242T polymorphism, which has been extensively studied in association with coronary artery and heart diseases, but conflicting results continue to be reported. [Review]

  6. C242T single-nucleotide polymorphism causes p22(phox) structural changes that inhibit endothelial Nox2 (显示 CYBB ELISA试剂盒) activation and oxidative response to tumor necrosis factor-alpha (显示 TNF ELISA试剂盒) or high-glucose stimulation. C242T single-nucleotide polymorphism may represent a natural protective mechanism against inflammatory cardiovascular diseases.

  7. CYBA C242T correlates with microalbuminuria onset in the French DT1 cohort.

  8. Overexpression of p22phox is associated with increased migration/metastasis rate in melanoma.

  9. To evaluate the association between CYBA gene polymorphisms and ESRD, we genotyped five CYBA polymorphisms. Our results suggested that rs1049255 polymorphism of CYBA modified the risk of ESRD.

  10. Substance P (显示 TAC1 ELISA试剂盒) enhances tissue factor (显示 F3 ELISA试剂盒) release from granulocyte-macrophage colony-stimulating factor (显示 CSF2 ELISA试剂盒)-dependent macrophages via the p22phox/beta-arrestin 2 (显示 ARRB2 ELISA试剂盒)/Rho A (显示 RHOA ELISA试剂盒) signaling pathway.

Mouse (Murine) Cytochrome B-245, alpha Polypeptide (CYBA) interaction partners

  1. p22phox mRNA expression was increased in diet-induced obese (DIO) mice.

  2. The present study provides evidence that augmented EGFRtk impairs vascular function by NADPH oxidase (显示 NOX1 ELISA试剂盒)-dependent mechanism. Therefore, EGFRtk and oxidative stress should be potential targets to treat vascular dysfunction in TD2.

  3. Vascular hnRNP-C expression is regulated by ROS (显示 ROS1 ELISA试剂盒) derived from NADPH (显示 FDXR ELISA试剂盒) oxidases and that the effects of NADPH oxidase (显示 NOX1 ELISA试剂盒) on vascular activation are mediated in part by protein kinase (显示 CDK7 ELISA试剂盒) CK1alpha (显示 CSNK1A1 ELISA试剂盒).

  4. Enhanced p22(phox) expression causes vascular dysfunction through ERK1/2 (显示 MAPK1/3 ELISA试剂盒) and p38-mitogen-activated protein kinase (显示 MAPK14 ELISA试剂盒)-dependent mechanisms in male type 2 diabetic mice.

  5. The first quantitative characterization of the interactions made between the cytosolic regulators NOXO1 (显示 NOXO1 ELISA试剂盒) and NOXA1 (显示 NOXA1 ELISA试剂盒) and membrane-bound p22(phox), is presented.

  6. renal expression of Nox-2 (显示 CYBB ELISA试剂盒), p22(phox), and p47(phox), components of NADPH oxidase (显示 NOX1 ELISA试剂盒), are upregulated in GSD-Ia mice compared with controls

  7. cytochrome b558 expression is downregulated via the reduction of heme availability after NADPH oxidase (显示 NOX1 ELISA试剂盒) is inhibited by HO-1 (显示 HMOX1 ELISA试剂盒)

  8. LPS (显示 TLR4 ELISA试剂盒) treatment enhanced protein levels of p22(phox), a catalytic subunit of NADPH oxidase (显示 NOX1 ELISA试剂盒), and increased NADPH oxidase (显示 NOX1 ELISA试剂盒) activity and levels of superoxide radicals and hydrogen peroxide.

  9. p22phox expression was increased during glucose-induced oxidative stress in microvascular endothelial cells.

  10. collagen synthesis in cardiac fibroblasts involves a facilitative interaction between TGFbeta (显示 TGFB1 ELISA试剂盒)(1)-NADPH oxidase (显示 NOX1 ELISA试剂盒) and LOX-1 (显示 OLR1 ELISA试剂盒)

Pig (Porcine) Cytochrome B-245, alpha Polypeptide (CYBA) interaction partners

  1. Upregulation of PPAR-gamma and NADPH oxidases are involved in restenosis.

  2. CRP (显示 CRP ELISA试剂盒) inhibits endothelium-dependent NO-mediated dilation in coronary arterioles by producing superoxide from NAD(P)H (显示 NQO1 ELISA试剂盒) oxidase via p38 (显示 MAPK14 ELISA试剂盒) kinase activation

  3. Reactive oxygen species generated by NADPH oxidase (显示 NOX1 ELISA试剂盒) contribute to the aberrant pulmonary arterial responses in piglets exposed to 3 days of hypoxia.

Rabbit Cytochrome B-245, alpha Polypeptide (CYBA) interaction partners

  1. Angiotensin II inhibits the Na+/K+ pump via protein kinase c epsilon (显示 PRKCE ELISA试剂盒)-dependent activation of NADPH oxidase (显示 NOX1 ELISA试剂盒) subunits.

Cytochrome B-245, alpha Polypeptide (CYBA) 抗原简介

Antigen Summary

Cytochrome b is comprised of a light chain (alpha) and a heavy chain (beta). This gene encodes the light, alpha subunit which has been proposed as a primary component of the microbicidal oxidase system of phagocytes. Mutations in this gene are associated with autosomal recessive chronic granulomatous disease (CGD), that is characterized by the failure of activated phagocytes to generate superoxide, which is important for the microbicidal activity of these cells.

Alternative names and synonyms associated with Cytochrome B-245, alpha Polypeptide (CYBA)

  • cytochrome b-245, alpha polypeptide (cyba) Elisa Kit
  • cytochrome b-245, alpha polypeptide (CYBA) Elisa Kit
  • cytochrome b-245 light chain-like (LOC101328418) Elisa Kit
  • cytochrome b-245, alpha polypeptide (Cyba) Elisa Kit
  • p22-phox (CYBA) Elisa Kit
  • b558 Elisa Kit
  • CYBA Elisa Kit
  • MGC80750 Elisa Kit
  • nmf333 Elisa Kit
  • P22-PHOX Elisa Kit
  • p22phox Elisa Kit
  • zgc:66077 Elisa Kit

Protein level used designations for CYBA

P22phox , cytochrome b-245, alpha polypeptide , predicted cytochrome b-245, alpha polypeptide , Cytochrome b(558) alpha chain , Cytochrome b558 subunit alpha , Neutrophil cytochrome b 22 kDa polypeptide , Superoxide-generating NADPH oxidase light chain subunit , cytochrome b-245 light chain , flavocytochrome b558 (p22phox) , p22 phagocyte B-cytochrome , cytochrome b light chain , cytochrome b(558) alpha chain , cytochrome b(558) alpha-subunit , cytochrome b, alpha polypeptide , cytochrome b558 subunit alpha , flavocytochrome b-558 alpha polypeptide , neutrophil cytochrome b 22 kDa polypeptide , p22phox , superoxide-generating NADPH oxidase light chain subunit , cytochrome beta-558 , p22 phox , p22-phox , cytochrome b558 alpha-subunit , NADPH oxidase light chain subunit

GENE ID SPECIES
393551 Danio rerio
446853 Xenopus laevis
489664 Canis lupus familiaris
549234 Xenopus (Silurana) tropicalis
100135693 Ovis aries
101328418 Tursiops truncatus
1535 Homo sapiens
13057 Mus musculus
79129 Rattus norvegicus
281111 Bos taurus
397507 Sus scrofa
100008800 Oryctolagus cuniculus
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