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TCTP (显示 TPT1 ELISA试剂盒) interacted with Y-box-binding protein 1 (YBX1), and their interaction was localized to the N-terminal region of TCTP (显示 TPT1 ELISA试剂盒) and the 1-129 amino acid (aa) residues of YBX1. The interaction of TCTP (显示 TPT1 ELISA试剂盒) with YBX1 might cooperate or coordinate their functions in the control of diverse regulatory pathways in cancer cells.
YB-1 expression promotes pancreatic cancer metastasis that is inhibited by microRNA-216a.
findings point to YB-1 and NSUN2 (显示 NSUN2 ELISA试剂盒) as possible mediators of the process of transfer of specific mRNAs into exosomes, allowing us to speculate on an involvement of these proteins in the mRNA sorting via the recognition of the above motifs
YB-1 is induced by Shh (显示 SHH ELISA试剂盒) in CGNPs
FOXO3a (显示 FOXO3 ELISA试剂盒) nuclear expression was inversely correlated with YB-1 nuclear expression in prostate cancer tissues.
these findings define a mechanism of drug resistance through which YBX1 contributes to antiestrogen bypass in breast cancer cells
High YB1 expression is associated with Cisplatin Resistance in Gastric Cancer.
Using mass spectrometry analysis, this study discovered a distinct phosphorylation site, Ser (显示 SIGLEC1 ELISA试剂盒)-176, on YBX1. Overexpression of the YBX1-S176A (serine-to-alanine) mutant in either HEK293 cells or colon cancer HT29 cells showed dramatically reduced NF-kappaB (显示 NFKB1 ELISA试剂盒)-activating ability compared with that of WT-YBX1, confirming that Ser (显示 SIGLEC1 ELISA试剂盒)-176 phosphorylation is critical for the activation of NF-kappaB (显示 NFKB1 ELISA试剂盒) by YBX1.
Collectively, these findings demonstrate a novel role of YBX1 in maintaining the stemness of CSCs and metastasis, unveiling YBX1 as promising therapeutic target for NSCLC treatments.
These studies reveal the functional role of YB-1 in the Angiogenin (显示 ANG ELISA试剂盒)-mediated stress response program.
The amounts of YB-1 and YB-1 mRNA in rabbit organs and several cell lines.
results prove direct inhibitory action of YB-1 on its mRNA translation, while the positive effect of PABP (显示 PABPC1 ELISA试剂盒) is realized through displacing YB-1 from the regulatory element
this study shows that innate immunity activation by muramyl peptides is mediated via an interaction between YB1 and NOD2 (显示 NOD2 ELISA试剂盒)
In conclusion, TGF-beta (显示 TGFB1 ELISA试剂盒) signaling pathway may influence liver fibrosis by incorporating with YB-1, indicating that YB-1 could be a potential target for therapies against liver fibrosis.
Reduction in the expression of YBX1 and ILF3 (显示 MMP4 ELISA试剂盒) controls the expression of pluripotency-related genes in ESCs (显示 NR2E3 ELISA试剂盒), suggesting their roles in further regulation of the pluripotent state of ESCs (显示 NR2E3 ELISA试剂盒).
In the initial stage of myocyte differentiation, transcription of the YB-1 gene was regulated by E2F1 (显示 E2F1 ELISA试剂盒) and Sp1 (显示 SP1 ELISA试剂盒), and was then gradually replaced under the control of both MyoD (显示 MYOD1 ELISA试剂盒) and myogenin (显示 MYOG ELISA试剂盒).
YB-1 is a novel intracellular target of activated protein C (显示 PROC ELISA试剂盒) in renal ischemia-reperfusion injury
miR (显示 MLXIP ELISA试剂盒)-382 inhibits osteosarcoma metastasis and relapse by targeting YB-1 protein.
YB-1 was revealed in a population of Cajal bodies in 2-cell mouse embryos but not in other cells studied.
The effects of MIA/CD-RAP (显示 MIA ELISA试剂盒) on transcriptional regulation in chondrocytes, through the regulation of p54(nrb (显示 NONO ELISA试剂盒)) via YBX1 contributes to the understanding of chondrogenesis.
The formation of intracytoplasmic Gag-RNA complexes is facilitated by YB-1, which promotes MMTV virus assembly.
transcription factor; acts as a regulator of protein tyrosine phosphatase PTP1B expression
B box-binding protein
, CCAAT-binding transcription factor I subunit A
, DNA-binding protein B
, Y-box transcription factor
, Y-box-binding protein 1
, enhancer factor I subunit A
, major histocompatibility complex, class II, Y box-binding protein I
, nuclease sensitive element binding protein 1
, nuclease-sensitive element-binding protein 1
, CCAAT-binding transcription factor 1 subunit A
, DNA binding protein B
, Y box transcription factor
, enhancer factor 1 alpha
, enhancer factor 1 subunit A
, FRG Y
, frg y1
, frog Y-box proteins
, Y-box binding protein 1