电话:
400-7060-959
传真:
+86 10 56315212-8813
电子邮件:
orders@antibodies-online.cn

Sonic Hedgehog 抗体

(Sonic Hedgehog (SHH))
This gene encodes a protein that is instrumental in patterning the early embryo. It has been implicated as the key inductive signal in patterning of the ventral neural tube, the anterior-posterior limb axis, and the ventral somites. Of three human proteins showing sequence and functional similarity to the sonic hedgehog protein of Drosophila, this protein is the most similar. The protein is made as a precursor that is autocatalytically cleaved\; the N-terminal portion is soluble and contains the signalling activity while the C-terminal portion is involved in precursor processing. More importantly, the C-terminal product covalently attaches a cholesterol moiety to the N-terminal product, restricting the N-terminal product to the cell surface and preventing it from freely diffusing throughout the developing embryo. Defects in this protein or in its signalling pathway are a cause of holoprosencephaly (HPE), a disorder in which the developing forebrain fails to correctly separate into right and left hemispheres. HPE is manifested by facial deformities. It is also thought that mutations in this gene or in its signalling pathway may be responsible for VACTERL syndrome, which is characterized by vertebral defects, anal atresia, tracheoesophageal fistula with esophageal atresia, radial and renal dysplasia, cardiac anomalies, and limb abnormalities. Additionally, mutations in a long range enhancer located approximately 1 megabase upstream of this gene disrupt limb patterning and can result in preaxial polydactyly. [provided by RefSeq, Jul 2008].
Sonic Hedgehog 抗体  (AA 21-120) Sonic Hedgehog 抗体  (AA 21-120) Sonic Hedgehog 抗体 (AA 21-120) (ABIN731108)

SHH 适用: 人, 小鼠, 大鼠, Pig WB, ELISA, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated

Sonic Hedgehog 抗体  (AA 26-161) Sonic Hedgehog 抗体  (AA 26-161) Sonic Hedgehog 抗体 (AA 26-161) (ABIN969567)

SHH 适用: 人, 小鼠, 猴 WB, IHC, ELISA, FACS 宿主: 小鼠 Monoclonal 5H4 unconjugated

Sonic Hedgehog 抗体  (C-Term) Sonic Hedgehog 抗体  (C-Term) Sonic Hedgehog 抗体 (C-Term) (ABIN6391361)

Verified SHH 适用: 人, 小鼠 WB, ELISA, IF, FACS 宿主: 山羊 Polyclonal unconjugated

Sonic Hedgehog 抗体 by Grade

Find Sonic Hedgehog 抗体 with a specific Grade. The Grade listed below are among those available. Click on a link to go to the corresponding products.

Sonic Hedgehog 抗体 by 适用

Find Sonic Hedgehog 抗体 for a variety of species such as anti-Human Sonic Hedgehog, anti-Mouse Sonic Hedgehog, anti-Rat Sonic Hedgehog. The species listed below are among those available. Click on a link to go to the corresponding products.

Sonic Hedgehog 抗体 by 应用范围

Find Sonic Hedgehog 抗体 validated for a specific application such as WB, ELISA, IHC, IF (cc). Some of the available applications are listed below. Click on a link to go to the corresponding products.

Sonic Hedgehog 抗体 by 抗体来源

Find Sonic Hedgehog 抗体 with a specific 抗体来源. The 抗体来源 listed below are among those available. Click on a link to go to the corresponding products.

Sonic Hedgehog 抗体 by 抗原表位

Find Sonic Hedgehog 抗体 with a specific epitope. The epitopes listed below are among those available. Click on a link to go to the corresponding products.

Sonic Hedgehog 抗体 by 克隆形成能力

Find available monoclonal or polyclonal Sonic Hedgehog 抗体. Click on a link to go to the corresponding products.

Sonic Hedgehog 抗体 by 克隆

Find Sonic Hedgehog 抗体 with a specific 克隆. The 克隆 listed below are among those available. Click on a link to go to the corresponding products.

Sonic Hedgehog 抗体 by 标记

Find Sonic Hedgehog 抗体 with a specific conjugate such as Biotin, FITC, HRP. The conjugates listed below are among those available. Click on a link to go to the corresponding products.

Popular Sonic Hedgehog 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human, Mouse, Pig, Rat
Application WB, ELISA, IHC (p), IF (cc), IF (p), IHC (fro)
Validations
  • (10)
  • (6)
Cat. No. ABIN731108
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Monkey, Mouse
Application WB, IHC, ELISA, FACS
Validations
  • (1)
  • (6)
Cat. No. ABIN969567
Quantity 0.1 mg
Datasheet Datasheet
Reactivity Human, Mouse
Application WB, ELISA, IF, FACS
Validations
  • (5)
Cat. No. ABIN6391361
Quantity 100 μg
Datasheet Datasheet

Application WB, IHC
Validations
  • (7)
Cat. No. ABIN2781775
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, IHC, IP, ICC
Validations
  • (4)
Cat. No. ABIN7434161
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, IHC, IP, ICC
Validations
  • (4)
Cat. No. ABIN7426367
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application WB, IF, FACS, IHC (p)
Validations
  • (4)
Cat. No. ABIN6242830
Quantity 400 μL
Datasheet Datasheet
Reactivity Dog, Human, Monkey, Rat
Application WB, IF
Validations
  • (3)
Cat. No. ABIN1491248
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, IF
Validations
  • (3)
Cat. No. ABIN6147930
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Rat
Application WB, IHC (p)
Validations
  • (1)
  • (3)
Cat. No. ABIN3043230
Quantity 100 μg
Datasheet Datasheet
Reactivity Rat
Application WB, IHC, ICC
Validations
  • (4)
Cat. No. ABIN5013678
Quantity 100 μL
Datasheet Datasheet
Reactivity Mouse
Application WB, IHC, IP, ICC
Validations
  • (2)
Cat. No. ABIN7437287
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application IHC, ELISA
Validations
  • (2)
Cat. No. ABIN7242410
Quantity 200 μL
Datasheet Datasheet
Reactivity Mouse
Application WB, FACS
Validations
  • (2)
Cat. No. ABIN6242829
Quantity 400 μL
Datasheet Datasheet

Application WB, IHC, IHC (p)
Validations
  • (2)
Cat. No. ABIN6736667
Quantity 100 μL
Datasheet Datasheet

Latest Publications for our Sonic Hedgehog 抗体

Tessier, Madhu, Johnson, Shapiro, Risbud: "NFAT5/TonEBP controls early acquisition of notochord phenotypic markers, collagen composition, and sonic hedgehog signaling during mouse intervertebral disc embryogenesis." in: Developmental biology, (2019) (PubMed).

Gao, Li, Li: "Exendin-4 promotes the osteogenic differentiation of osteoblasts via the Hedgehog/Gli1 signaling pathway." in: American journal of translational research, Vol. 10, Issue 1, pp. 315-324, (2018) (PubMed).

Morales-Hernández, Nacarino-Palma, Moreno-Marín, Barrasa, Paniagua-Quiñones, Catalina-Fernández, Alvarez-Barrientos, Bustelo, Merino, Fernández-Salguero: "Lung regeneration after toxic injury is improved in absence of dioxin receptor." in: Stem cell research, Vol. 25, pp. 61-71, (2018) (PubMed).

Fan, Li, Liu, Cong, Zhao, Cao, Zheng: "Doxorubicin combined with low intensity ultrasound suppresses the growth of oral squamous cell carcinoma in culture and in xenografts." in: Journal of experimental & clinical cancer research : CR, Vol. 36, Issue 1, pp. 163, (2018) (PubMed).

Yang, Wu, Feng, Huang, Liu, Liu, Chen: "Vitamin C plus hydrogel facilitates bone marrow stromal cell-mediated endometrium regeneration in rats." in: Stem cell research & therapy, Vol. 8, Issue 1, pp. 267, (2017) (PubMed).

Song, Du, Tao: "Blockade of sonic hedgehog signaling decreases viability and induces apoptosis in retinoblastoma cells: The key role of the PI3K/Akt pathway." in: Oncology letters, Vol. 14, Issue 4, pp. 4099-4105, (2017) (PubMed).

Lozito, Tuan: "Lizard tail skeletal regeneration combines aspects of fracture healing and blastema-based regeneration." in: Development (Cambridge, England), Vol. 143, Issue 16, pp. 2946-57, (2016) (PubMed).

Valverde, Pereira, Dias, Guimarães, Ramos, Santos, Gurgel Rocha: "Macrophages and endothelial cells orchestrate tumor-associated angiogenesis in oral cancer via hedgehog pathway activation." in: Tumour biology, Vol. 37, Issue 7, pp. 9233-41, (2016) (PubMed).

Vidal, Lourenço, Soares, Gurgel, Studart, Valverde, Araújo, Ramos, Xavier, Dos Santos: "The sonic hedgehog signaling pathway contributes to the development of salivary gland neoplasms regardless of perineural infiltration." in: Tumour biology, Vol. 37, Issue 7, pp. 9587-601, (2016) (PubMed).

Wang, Zhang, Bai, Wang, Du: "Baicalin Attenuates Alcoholic Liver Injury through Modulation of Hepatic Oxidative Stress, Inflammation and Sonic Hedgehog Pathway in Rats." in: Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, Vol. 39, Issue 3, pp. 1129-40, (2016) (PubMed).

Aliases for Sonic Hedgehog 抗体

sonic hedgehog (SHH) 抗体
sonic hedgehog (Shh) 抗体
sonic hedgehog a (shha) 抗体
sonic hedgehog L homeolog (shh.L) 抗体
sonic hedgehog (shh) 抗体
sonic hedgehog protein A (shh) 抗体
sonic hedgehog b (shhb) 抗体
9530036O11Rik 抗体
Dsh 抗体
fc83d08 抗体
hedgehog 抗体
HHG1 抗体
Hhg1 抗体
HLP3 抗体
HPE3 抗体
Hx 抗体
Hxl3 抗体
M100081 抗体
MCOPCB5 抗体
shh 抗体
SHH 抗体
SMMCI 抗体
syu 抗体
TPT 抗体
TPTPS 抗体
twh 抗体
twhh 抗体
vhh-1 抗体
vhh1 抗体
wu:fc83d08 抗体
Xhh 抗体
xshh 抗体

您还需要查找其他产品吗?

You are here:
客服