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抗Human MED31 抗体:
抗Rat (Rattus) MED31 抗体:
抗Mouse (Murine) MED31 抗体:
Results show that miR-1 (显示 FSD1 抗体) is downregulated in osteosarcoma cells but both of its targets Med1 (显示 MED1 抗体) and Med31 were overexpressed suggesting that MiR-1 (显示 FSD1 抗体) plays an important role on the proliferation of osteosarcoma cells through regulation of Med1 (显示 MED1 抗体) and Med31.
Elmo1 (显示 ELMO1 抗体) increased the cytoplasmic localization of Med31.
As the Mediator complex is a transcriptional co-activator, results suggest that Med31 functions to promote the transcription of genes required for embryonic growth and cell proliferation.
Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors (By similarity).
mediator complex subunit 31
, mediator complex subunit soh1
, mediator of RNA polymerase II transcription subunit 31
, mediator of RNA polymerase II transcription, subunit 31 homolog
, hypothetical protein
, mediator complex subunit SOH1