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抗Human MED19 抗体:
抗Rat (Rattus) MED19 抗体:
抗Mouse (Murine) MED19 抗体:
Bat Polyclonal MED19 Primary Antibody for WB - ABIN610993
Hernando, Martin-Vasallo, Ghosh, Ghosh, Swaroop, Coca-Prados: Nucleotide sequence of a cDNA for the beta 2 subunit isoform of Na+,K(+)-ATPase from human retina. in Biochimica et biophysica acta 1994
Show all 3 Pubmed References
Rat (Rattus) Polyclonal MED19 Primary Antibody for WB - ABIN4893986
Rienzo, Casamassimi, Schiano, Grimaldi, Infante, Napoli: Distinct alternative splicing patterns of mediator subunit genes during endothelial progenitor cell differentiation. in Biochimie 2012
Cow (Bovine) Polyclonal MED19 Primary Antibody for WB - ABIN2786281
Agaësse, Barbollat-Boutrand, Sulpice, Bhajun, Kharbili, Berthier-Vergnes, Degoul, de la Fouchardière, Berger, Voeltzel, Lamartine, Gidrol, Masse: A large-scale RNAi screen identifies LCMR1 as a critical regulator of Tspan8-mediated melanoma invasion. in Oncogene 2016
supports a role for Med19 as a PolII holoenzyme-embedded "co-factor" that acts together with Hox (显示 MSH2 抗体) proteins through their homeodomains in regulated developmental transcription
LCMR1 modulation was sufficient to positively regulate endogenous Tspan8 (显示 TSPAN8 抗体) expression, with concomitant in vitro phenotypic changes such as loss of melanoma cell-matrix adherence and increase in invasion, and Tspan8 (显示 TSPAN8 抗体) expression promoted tumourigenicity in vivo.
We knocked down the Med19 expression in prostate cancer cell lines LNCaP and PC3 (显示 PCSK1 抗体) by using lentivirus siRNA. Cell proliferation, anchor-independent growth, migration, and invasion were suppressed in Med19 knockdown prostate cancer cells.
Med19 promotes breast cancer cell proliferation and that this effect is associated with regulating CBFA2T3 (显示 CBFA2T3 抗体) and HEB (显示 TCF12 抗体) expression.
FOXD3 (显示 FOXD3 抗体)/miR (显示 MLXIP 抗体)-214/MED19 axis is important for the regulation of growth, invasion and metastasis of colorectal cancer
High expression of Med19 is associated with cisplatin resistance in non-small cell lung cancer cells.
Data show that the expression of Mediator of RNA polymerase II transcription subunit 19 (Med19) was increased in Osteosarcoma (OS) samples from patients compared to normal bone tissues.
High Med19 expression is associated with tongue cancer.
Med19 promotes bone metastasis and invasiveness of bladder urothelial carcinoma via bone morphogenetic protein 2 (显示 BMP2 抗体).
Med19 is markedly up-regulated in bladder cancer tissues
LCMR1 suppresses apoptosis in lung cancer cells and this effect is associated with multiple apoptosis-related proteins, including p53 (显示 TP53 抗体), Bax (显示 BAX 抗体) and Mcl-1 (显示 MCL1 抗体).
MED19 is a component of the Mediator complex, which is a coactivator for DNA-binding factors that activate transcription via RNA polymerase II (Sato et al., 2003
mediator complex subunit 19
, mediator of RNA polymerase II transcription, subunit 19 homolog (S. cerevisiae)
, mediator of RNA polymerase II transcription, subunit 19 homolog
, mediator of RNA polymerase II transcription subunit 19
, lung cancer metastasis-related protein 1