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anti-Hepatitis A Virus Cellular Receptor 2 (HAVCR2) 抗体产品概述

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anti-Hepatitis A Virus Cellular Receptor 2 抗体 (HAVCR2)
在www.antibodies-online.cn可供199 Hepatitis A Virus Cellular Receptor 2 (HAVCR2) 抗体的22不同的供货商。 再加上,我们可以发Hepatitis A Virus Cellular Receptor 2 蛋白 (36)Hepatitis A Virus Cellular Receptor 2 试剂盒 (7)和数多这个蛋白质的别的产品。 总共256 Hepatitis A Virus Cellular Receptor 2产品已列进来了。
别名:
HAVcr-2, HAVCR2, KIM-3, MGC140131, TIM-3, tim3, TIMD-3, Timd3
列出全部抗体 基因 基因ID UniProt
HAVCR2 84868 Q8TDQ0
HAVCR2 171285 Q8VIM0
HAVCR2 363578  

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引用最多的anti-Hepatitis A Virus Cellular Receptor 2 抗体

  1. Human Monoclonal HAVCR2 Primary Antibody for FACS - ABIN4896442 : Tandon, Giret, Sengupta, York, Wiznia, Rosenberg, Kallas, Ndhlovu, Nixon: Age-related expansion of Tim-3 expressing T cells in vertically HIV-1 infected children. in PLoS ONE 2012 (PubMed)
    Show all 15 references for ABIN4896442

  2. Human Monoclonal HAVCR2 Primary Antibody for FACS - ABIN4899648 : Hertoghs, Moerland, van Stijn, Remmerswaal, Yong, van de Berg, van Ham, Baas, ten Berge, van Lier: Molecular profiling of cytomegalovirus-induced human CD8+ T cell differentiation. in The Journal of clinical investigation 2010 (PubMed)
    Show all 5 references for ABIN4899648

  3. Human Monoclonal HAVCR2 Primary Antibody for FACS - ABIN4896438 : Raziorrouh, Heeg, Kurktschiev, Schraut, Zachoval, Wendtner, Wächtler, Spannagl, Denk, Ulsenheimer, Bengsch, Pircher, Diepolder, Grüner, Jung: Inhibitory phenotype of HBV-specific CD4+ T-cells is characterized by high PD-1 expression but absent coregulation of multiple inhibitory molecules. in PLoS ONE 2014 (PubMed)
    Show all 5 references for ABIN4896438

  4. Mouse (Murine) Monoclonal HAVCR2 Primary Antibody for FACS - ABIN4896162 : Cho, Roche, Sandall, Brass, Seed, Xavier, Medoff: Enhanced Tim3 activity improves survival after influenza infection. in Journal of immunology (Baltimore, Md. : 1950) 2012 (PubMed)
    Show all 3 references for ABIN4896162

  5. Human Monoclonal HAVCR2 Primary Antibody for FACS - ABIN4896440 : Leeansyah, Svärd, Dias, Buggert, Nyström, Quigley, Moll, Sönnerborg, Nowak, Sandberg: Arming of MAIT Cell Cytolytic Antimicrobial Activity Is Induced by IL-7 and Defective in HIV-1 Infection. in PLoS pathogens 2015 (PubMed)
    Show all 2 references for ABIN4896440

  6. Human Monoclonal HAVCR2 Primary Antibody for FACS - ABIN4896439 : Lasso, Mateus, Pavía, Rosas, Roa, Thomas, López, González, Puerta, Cuéllar: Inhibitory Receptor Expression on CD8+ T Cells Is Linked to Functional Responses against Trypanosoma cruzi Antigens in Chronic Chagasic Patients. in Journal of immunology (Baltimore, Md. : 1950) 2015 (PubMed)
    Show all 2 references for ABIN4896439

  7. Dog (Canine) Polyclonal HAVCR2 Primary Antibody for WB - ABIN374646 : Meyers, Sabatos, Chakravarti, Kuchroo: The TIM gene family regulates autoimmune and allergic diseases. in Trends in molecular medicine 2005 (PubMed)

  8. Human Monoclonal HAVCR2 Primary Antibody for FACS - ABIN4896441 : Lanteri, Diamond, Law, Chew, Wu, Inglis, Wong, Busch, Norris, Ndhlovu: Increased frequency of Tim-3 expressing T cells is associated with symptomatic West Nile virus infection. in PLoS ONE 2014 (PubMed)

  9. Human Polyclonal HAVCR2 Primary Antibody for WB - ABIN2782255 : Nuchnoi, Ohashi, Kimura, Hananantachai, Naka, Krudsood, Looareesuwan, Tokunaga, Patarapotikul: Significant association between TIM1 promoter polymorphisms and protection against cerebral malaria in Thailand. in Annals of human genetics 2008 (PubMed)

更多抗Hepatitis A Virus Cellular Receptor 2的相互作用对抗体

Cow (Bovine) Hepatitis A Virus Cellular Receptor 2 (HAVCR2) interaction partners

  1. The Tim-3/Gal-9 (显示 LGALS9 抗体) pathway might link disease progression with T cell exhaustion during bovine leukemia virus infection.

Human Hepatitis A Virus Cellular Receptor 2 (HAVCR2) interaction partners

  1. Tim-3 blockade in combination with TLR activation induces the expression of antiviral molecules without a significant increase in TNF-alpha (显示 TNF 抗体) or SOCS1 (显示 SOCS1 抗体).

  2. this study shows that the expression of TIM-3 is correlated with advanced stage and could be independent risk factors for colorectal cancer

  3. Immune checkpoint proteins are co-inhibitory factors that can diminish the antigen-specific immune responses by attenuating the regulatory role of cytotoxic T-lymphocyte-associated protein 4 (显示 CTLA4 抗体), programmed cell death-1 (显示 PDCD1 抗体), lymphocyte-activation gene 3 (显示 LAG3 抗体), and T-cell immunoglobulin mucin-3.

  4. TLR2 (显示 TLR2 抗体), Tim1 (显示 ARHGEF5 抗体), Tim3, TNF-alpha (显示 TNF 抗体), IgE and EOS (显示 IKZF4 抗体) play a role in Mycoplasma pneumoniae Pneumonia-related wheezing in children.

  5. The results of our study showed that there is no significant association between TIM-1 (显示 ARHGEF5 抗体) 5383-5397ins/del and Multiple sclerosis (MS) (P = 0.38); however, the frequency of CT genotype of TIM-3 -1541C>T in patient group was significantly higher than the control group, and there was a significant association between CT genotype and MS

  6. this study shoes that Tim-3 level is significantly upregulated in monocytes from gastric cancer patients compared with those from healthy controls

  7. these results suggest that TIM3 is a novel therapeutic target and prognostic biomarker for esophageal squamous cell carcinoma (ESCC) and promotes metastasis of ESCC by inducing epithelial-mesenchymal transition via, at least partially, the Akt (显示 AKT1 抗体)/GSK-3beta (显示 GSK3b 抗体)/Snail (显示 SNAI1 抗体) signaling pathway.

  8. Tim-3 facilitates osteosarcoma proliferation and metastasis through the NF-kappaB (显示 NFKB1 抗体) pathway and epithelial-mesenchymal transition.

  9. Studied the associations of T-cell immunoglobulin and mucin (显示 SLC13A2 抗体) domain-3 (Tim-3) polymorphisms and the alternate reading frame protein (F protein (显示 HPD 抗体)) with the outcomes of HCV infection; findings suggest that the rs12186731 CT and rs13170556 TC/CC genotypes of Tim-3 provide potential protective effects with the F protein (显示 HPD 抗体) in the outcomes of HCV infection and that these effects are related to sex and age.

  10. this study shows that the levels of expression of TIM-3 on CD4 (显示 CD4 抗体)+ T cells, CD8 (显示 CD8A 抗体)+ T cells, CD56 (显示 NCAM1 抗体)+ T cells and in serum in patients with systemic lupus erythematosus are significantly higher than those of healthy controls

Mouse (Murine) Hepatitis A Virus Cellular Receptor 2 (HAVCR2) interaction partners

  1. Methylation level of the TIM-3 promoter gradually decreased after each round of T-cell polarization, and this decrease was inversely correlated with TIM-3 expression.

  2. in mice, TIM-3 is not essential for development of HDM (显示 HDAC3 抗体)-induced acute or chronic allergic airway inflammation, although it appears to be involved in reduced lymphocyte recruitment during HDM (显示 HDAC3 抗体)-induced chronic allergic airway inflammation.

  3. Authors found that a CD8 (显示 CD8A 抗体)(+) T-cell population with age-associated exhaustion was distinguishable by its expression of Tim-3.

  4. TIM4 (显示 TIMD4 抗体) binds TIM3 on the surface of polarized Th1 (显示 HAND1 抗体) cells to induce Th1 (显示 HAND1 抗体) cell apoptosis, which may contribute to the development of Th2-dominant immune disorders.

  5. The Gal-9 (显示 LGALS9 抗体)/Tim-3 signal is important for the regulation of decidua NK cells function, which is beneficial for the maintenance of a normal pregnancy.

  6. TIM-3 expression by NK cells and gamma/delta T cells is similar in the peripheral and decidual immune cells from pregnant mice.

  7. Tim-3 acts at a receptor-proximal point to enhance Lyn (显示 LYN 抗体) kinase-dependent signaling pathways that modulate both immediate-phase degranulation and late-phase cytokine production downstream of FcepsilonRI (显示 FCER1A 抗体) ligation.

  8. Our data indicate that Tim-3 expression on NK cells is regulated by T-bet, and that Tim-3 levels correlate with advanced stages of gastric cancer

  9. TIM-3 plays a role in regulating the uterine natural killer cells and contributes to the maintenance of tolerance at the feto-maternal interface.

  10. TIM-3 is highly expressed in hypoxic brain regions of a mouse cerebral hypoxia-ischaemia (H/I) model. TIM-3 is distinctively upregulated in activated microglia and astrocytes in a HIF-1 (显示 HIF1A 抗体)-dependent manner.

Hepatitis A Virus Cellular Receptor 2 (HAVCR2) 抗原简介

Antigen Summary

The protein encoded by this gene belongs to the immunoglobulin superfamily, and TIM family of proteins. CD4-positive T helper lymphocytes can be divided into types 1 (Th1) and 2 (Th2) on the basis of their cytokine secretion patterns. Th1 cells are involved in cell-mediated immunity to intracellular pathogens and delayed-type hypersensitivity reactions, whereas, Th2 cells are involved in the control of extracellular helminthic infections and the promotion of atopic and allergic diseases. This protein is a Th1-specific cell surface protein that regulates macrophage activation, and inhibits Th1-mediated auto- and alloimmune responses, and promotes immunological tolerance.

Alternative names and synonyms associated with Hepatitis A Virus Cellular Receptor 2 (HAVCR2)

  • hepatitis A virus cellular receptor 2 (HAVCR2) 抗体
  • hepatitis A virus cellular receptor 2 (Havcr2) 抗体
  • HAVcr-2 抗体
  • HAVCR2 抗体
  • KIM-3 抗体
  • MGC140131 抗体
  • TIM-3 抗体
  • tim3 抗体
  • TIMD-3 抗体
  • Timd3 抗体

Protein level used designations for HAVCR2

hepatitis A virus cellular receptor 2 , T cell immunoglobulin mucin 3 , T cell immunoglobulin mucin-3 , T-cell immunoglobulin and mucin domain-containing protein 3 , T-cell membrane protein 3 , kidney injury molecule-3 , HAVcr-2 , T-cell immunoglobulin and mucin domain containing 3 , TIMD-3 , hepatitis A virus cellular receptor 2 homolog , TIM-3

GENE ID SPECIES
462219 Pan troglodytes
768047 Bos taurus
84868 Homo sapiens
171285 Mus musculus
363578 Rattus norvegicus
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