anti-Hepatitis A Virus Cellular Receptor 2 (HAVCR2) 抗体产品概述

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anti-Hepatitis A Virus Cellular Receptor 2 抗体 (HAVCR2)
在www.antibodies-online.cn可供216 Hepatitis A Virus Cellular Receptor 2 (HAVCR2) 抗体的24不同的供货商。 再加上,我们可以发Hepatitis A Virus Cellular Receptor 2 蛋白 (41)Hepatitis A Virus Cellular Receptor 2 试剂盒 (8)和数多这个蛋白质的别的产品。 总共279 Hepatitis A Virus Cellular Receptor 2产品已列进来了。
别名:
HAVcr-2, HAVCR2, KIM-3, MGC140131, TIM-3, tim3, TIMD-3, Timd3
列出全部抗体 基因 基因ID UniProt
HAVCR2 84868 Q8TDQ0
HAVCR2 171285 Q8VIM0
HAVCR2 363578  

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  1. Human Monoclonal HAVCR2 Primary Antibody for FACS - ABIN4896442 : Tandon, Giret, Sengupta, York, Wiznia, Rosenberg, Kallas, Ndhlovu, Nixon: Age-related expansion of Tim-3 expressing T cells in vertically HIV-1 infected children. in PLoS ONE 2012 (PubMed)
    Show all 15 references for 4896442

  2. Human Monoclonal HAVCR2 Primary Antibody for FACS - ABIN4899648 : Hertoghs, Moerland, van Stijn, Remmerswaal, Yong, van de Berg, van Ham, Baas, ten Berge, van Lier: Molecular profiling of cytomegalovirus-induced human CD8+ T cell differentiation. in The Journal of clinical investigation 2010 (PubMed)
    Show all 5 references for 4899648

  3. Human Monoclonal HAVCR2 Primary Antibody for FACS - ABIN4896438 : Raziorrouh, Heeg, Kurktschiev, Schraut, Zachoval, Wendtner, Wächtler, Spannagl, Denk, Ulsenheimer, Bengsch, Pircher, Diepolder, Grüner, Jung: Inhibitory phenotype of HBV-specific CD4+ T-cells is characterized by high PD-1 expression but absent coregulation of multiple inhibitory molecules. in PLoS ONE 2014 (PubMed)
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  4. Mouse (Murine) Monoclonal HAVCR2 Primary Antibody for FACS - ABIN4896162 : Cho, Roche, Sandall, Brass, Seed, Xavier, Medoff: Enhanced Tim3 activity improves survival after influenza infection. in Journal of immunology (Baltimore, Md. : 1950) 2012 (PubMed)
    Show all 3 references for 4896162

  5. Mouse (Murine) Monoclonal HAVCR2 Primary Antibody for FACS - ABIN4896159 : Yadav, Jhunjhunwala, Phung, Lupardus, Tanguay, Bumbaca, Franci, Cheung, Fritsche, Weinschenk, Modrusan, Mellman, Lill, Delamarre: Predicting immunogenic tumour mutations by combining mass spectrometry and exome sequencing. in Nature 2014 (PubMed)
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  6. Human Monoclonal HAVCR2 Primary Antibody for FACS - ABIN4896440 : Leeansyah, Svärd, Dias, Buggert, Nyström, Quigley, Moll, Sönnerborg, Nowak, Sandberg: Arming of MAIT Cell Cytolytic Antimicrobial Activity Is Induced by IL-7 and Defective in HIV-1 Infection. in PLoS pathogens 2015 (PubMed)
    Show all 2 references for 4896440

  7. Human Monoclonal HAVCR2 Primary Antibody for FACS - ABIN4896439 : Lasso, Mateus, Pavía, Rosas, Roa, Thomas, López, González, Puerta, Cuéllar: Inhibitory Receptor Expression on CD8+ T Cells Is Linked to Functional Responses against Trypanosoma cruzi Antigens in Chronic Chagasic Patients. in Journal of immunology (Baltimore, Md. : 1950) 2015 (PubMed)
    Show all 2 references for 4896439

  8. Dog (Canine) Polyclonal HAVCR2 Primary Antibody for WB - ABIN2782255 : Nuchnoi, Ohashi, Kimura, Hananantachai, Naka, Krudsood, Looareesuwan, Tokunaga, Patarapotikul: Significant association between TIM1 promoter polymorphisms and protection against cerebral malaria in Thailand. in Annals of human genetics 2008 (PubMed)

  9. Human Polyclonal HAVCR2 Primary Antibody for ELISA, WB - ABIN185571 : Meyers, Sabatos, Chakravarti, Kuchroo: The TIM gene family regulates autoimmune and allergic diseases. in Trends in molecular medicine 2005 (PubMed)

  10. Human Monoclonal HAVCR2 Primary Antibody for FACS - ABIN4896441 : Lanteri, Diamond, Law, Chew, Wu, Inglis, Wong, Busch, Norris, Ndhlovu: Increased frequency of Tim-3 expressing T cells is associated with symptomatic West Nile virus infection. in PLoS ONE 2014 (PubMed)

更多抗Hepatitis A Virus Cellular Receptor 2的相互作用对抗体

Cow (Bovine) Hepatitis A Virus Cellular Receptor 2 (HAVCR2) interaction partners

  1. The Tim-3/Gal-9 (显示 LGALS9 抗体) pathway might link disease progression with T cell exhaustion during bovine leukemia virus infection.

Human Hepatitis A Virus Cellular Receptor 2 (HAVCR2) interaction partners

  1. this study shows that severe aplastic anemia untreated patients have lower TIM-3 expression on NK cells and CD56dim NK subsets compared with normal controls, and are correlated with the severity of pancytopenia of SAA (显示 SAA1 抗体)

  2. We conclude that Tim-3 is a biomarker of dysfunctional plasmacytoid dendritic cells

  3. The present study defines the minimal TIM-3 promoter region and demonstrates its interaction with c-Jun (显示 JUN 抗体) during TIM-3 transcription in CD4 (显示 CD4 抗体)(+) T cells.

  4. Our findings establish intratumoral Tim-3(+)PD1 (显示 PDCD1 抗体)(+)CD8 (显示 CD8A 抗体)(+) T cells as critical mediators of an aggressive phenotype in RCC (显示 XRCC1 抗体).

  5. Osteosarcoma patients with higher Tim-3 had relatively lower survival. Multivariate analyses for overall survival revealed that high serum soluble Tim-3 level was an independent prognostic factor for osteosarcoma

  6. urther analyses revealed that the levels of Tim-3 on CD4 (显示 CD4 抗体)+ T cells and CD8 (显示 CD8A 抗体)+ T cells exhibited different expression patterns in terms of localization depending on pathological category of prostate cancer and metastasis. Immunohistochemical analysis revealed that positive staining of Tim-3 in prostate cancer but little or no staining of Tim-3 was observed in benign prostate hyperplasia epithelium.

  7. this review discusses the recent findings on Tim-3, the role it plays in regulating immune responses in different cell types and the rationale for targeting Tim-3 for effective cancer immunotherapy

  8. The -1516G > T, -574G > T and +4259T > G SNPs within TIM-3 gene might play an important role as a genetic risk factor in the pathogenesis of ET.

  9. this study shows that that Tim-3 expression defines a subpopulation of PD-1 (显示 PDCD1 抗体)+ exhausted NY-ESO-1 (显示 CTAG1B 抗体)-specific CD8 (显示 CD8A 抗体)+ T cell and PD-1 (显示 PDCD1 抗体)+Tim-3+ CD8 (显示 CD8A 抗体)+ T cells represented the largest subset of NY-ESO-1 (显示 CTAG1B 抗体)-specific CD8 (显示 CD8A 抗体)+ T cells in gastric cancer patients

  10. Increased TIM3+CD8 (显示 CD8A 抗体)+T cells with lower perforin (显示 PRF1 抗体) and granzyme B (显示 Gzmb 抗体) expression and higher CD95 (显示 FAS 抗体) expression in MDS (显示 PAFAH1B1 抗体) patients had been observed. These findings suggested that TIM3 might be related to CD8 (显示 CD8A 抗体)+T cells defect.

Mouse (Murine) Hepatitis A Virus Cellular Receptor 2 (HAVCR2) interaction partners

  1. demonstrated that both IL-10 (显示 IL10 抗体) and TGF-beta (显示 TGFB1 抗体) upregulated TIM-3 surface expression on dendritic cells via a common signaling pathway that involved sequential activation of c-Src (显示 SRC 抗体) and Bruton's tyrosine kinase (显示 BTK 抗体)

  2. Methylation level of the TIM-3 promoter gradually decreased after each round of T-cell polarization, and this decrease was inversely correlated with TIM-3 expression.

  3. in mice, TIM-3 is not essential for development of HDM (显示 HDAC3 抗体)-induced acute or chronic allergic airway inflammation, although it appears to be involved in reduced lymphocyte recruitment during HDM (显示 HDAC3 抗体)-induced chronic allergic airway inflammation.

  4. Authors found that a CD8 (显示 CD8A 抗体)(+) T-cell population with age-associated exhaustion was distinguishable by its expression of Tim-3.

  5. TIM4 (显示 TIMD4 抗体) binds TIM3 on the surface of polarized Th1 (显示 HAND1 抗体) cells to induce Th1 (显示 HAND1 抗体) cell apoptosis, which may contribute to the development of Th2-dominant immune disorders.

  6. The Gal-9 (显示 LGALS9 抗体)/Tim-3 signal is important for the regulation of decidua NK cells function, which is beneficial for the maintenance of a normal pregnancy.

  7. TIM-3 expression by NK cells and gamma/delta T cells is similar in the peripheral and decidual immune cells from pregnant mice.

  8. Tim-3 acts at a receptor-proximal point to enhance Lyn (显示 LYN 抗体) kinase-dependent signaling pathways that modulate both immediate-phase degranulation and late-phase cytokine production downstream of FcepsilonRI (显示 FCER1A 抗体) ligation.

  9. Our data indicate that Tim-3 expression on NK cells is regulated by T-bet, and that Tim-3 levels correlate with advanced stages of gastric cancer

  10. TIM-3 plays a role in regulating the uterine natural killer cells and contributes to the maintenance of tolerance at the feto-maternal interface.

Hepatitis A Virus Cellular Receptor 2 (HAVCR2) 抗原简介

Antigen Summary

The protein encoded by this gene belongs to the immunoglobulin superfamily, and TIM family of proteins. CD4-positive T helper lymphocytes can be divided into types 1 (Th1) and 2 (Th2) on the basis of their cytokine secretion patterns. Th1 cells are involved in cell-mediated immunity to intracellular pathogens and delayed-type hypersensitivity reactions, whereas, Th2 cells are involved in the control of extracellular helminthic infections and the promotion of atopic and allergic diseases. This protein is a Th1-specific cell surface protein that regulates macrophage activation, and inhibits Th1-mediated auto- and alloimmune responses, and promotes immunological tolerance.

Alternative names and synonyms associated with Hepatitis A Virus Cellular Receptor 2 (HAVCR2)

  • hepatitis A virus cellular receptor 2 (HAVCR2) 抗体
  • hepatitis A virus cellular receptor 2 (Havcr2) 抗体
  • HAVcr-2 抗体
  • HAVCR2 抗体
  • KIM-3 抗体
  • MGC140131 抗体
  • TIM-3 抗体
  • tim3 抗体
  • TIMD-3 抗体
  • Timd3 抗体

Protein level used designations for HAVCR2

hepatitis A virus cellular receptor 2 , T cell immunoglobulin mucin 3 , T cell immunoglobulin mucin-3 , T-cell immunoglobulin and mucin domain-containing protein 3 , T-cell membrane protein 3 , kidney injury molecule-3 , HAVcr-2 , T-cell immunoglobulin and mucin domain containing 3 , TIMD-3 , hepatitis A virus cellular receptor 2 homolog , TIM-3

GENE ID SPECIES
462219 Pan troglodytes
768047 Bos taurus
84868 Homo sapiens
171285 Mus musculus
363578 Rattus norvegicus
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