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Mouse (Murine) APOA1 ELISA Kit for Sandwich ELISA - ABIN367803
Wang, Xia, Gao, Li, Zhang, Jin, Ling: Cyanidin-3-O-β-glucoside upregulates hepatic cholesterol 7α-hydroxylase expression and reduces hypercholesterolemia in mice. in Molecular nutrition & food research 2012
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Rat (Rattus) APOA1 ELISA Kit for Sandwich ELISA - ABIN368046
Safarzade, Talebi-Garakani: Short term resistance training enhanced plasma apoA-I and FABP4 levels in Streptozotocin-induced diabetic rats. in Journal of diabetes and metabolic disorders 2014
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Human APOA1 ELISA Kit for Sandwich ELISA - ABIN366758
Li, Li, Zhang, Li, Liu, Chang: Discovery of Apo-A1 as a potential bladder cancer biomarker by urine proteomics and analysis. in Biochemical and biophysical research communications 2014
Rabbit APOA1 ELISA Kit for Sandwich ELISA - ABIN365704
Liaw, Lin, Lai, Yang, Wang, Whang-Peng, Liu, Lin, Nieh, Lu, Hwang: A Vaccine Targeted at CETP Alleviates High Fat and High Cholesterol Diet-Induced Atherosclerosis and Non-Alcoholic Steatohepatitis in Rabbit. in PLoS ONE 2014
Findings suggest that the ABCG1 (显示 ABCG1 ELISA试剂盒)-mediated efflux of cholesterol, but not of 7-ketocholesterol, shows specificity for structural domains of apoA-I bound to reconstituted HDL (显示 HSD11B1 ELISA试剂盒). Although the mid region alone of apoA-I associated to rHDL can promote ABCG1 (显示 ABCG1 ELISA试剂盒)-mediated cholesterol efflux, deletion of carboxyl-terminal region 185-243 from full-length apoA-I diminishes ABCG1 (显示 ABCG1 ELISA试剂盒)-mediated cholesterol efflux.
Low APOA1 expression is associated with coronary artery disease severity.
Data suggest that activation of SR-BI (显示 SCARB1 ELISA试剂盒) by APOAI down-regulates sphingosine 1-phosphate/S1PR2 (显示 S1PR2 ELISA试剂盒)-mediated inflammation in vascular endothelial cells by activating the PI3K (显示 PIK3CA ELISA试剂盒)/Akt (显示 AKT1 ELISA试剂盒) signaling pathway; oxidized-LDL does the opposite. (APOA1 = apolipoprotein A-I; SR-BI/SCARB1 (显示 SCARB1 ELISA试剂盒) = scavenger receptor class B type I; S1PR2 (显示 S1PR2 ELISA试剂盒) = sphingosine 1-phosphate receptor 2 (显示 S1PR2 ELISA试剂盒); PI3K (显示 PIK3CA ELISA试剂盒) = phosphatidylinositol 3-kinase; Akt (显示 AKT1 ELISA试剂盒) = proto-oncogene c-akt (显示 AKT1 ELISA试剂盒))
The minor alleles of rs662799 (APOA5 (显示 APOA5 ELISA试剂盒)) and rs5072 (APOA1) modulate TG levels in Mexican children
Objective of this study was to understand their structural and functional role by generating domain swapped chimeras: apoE3-N-terminal/apoAI-C-terminal and apoAI-N-terminal/apoE (显示 APOE ELISA试剂盒)-C-terminal. Results indicate that the functional attributes of apoAI and apoE3 can be conferred on each other and that N-terminal-C-terminal domain interactions significantly modulate their structure and function.
These data demonstrate that complex of PPARgamma (显示 PPARG ELISA试剂盒) with GW1929 is a negative regulator involved in the control of ApoA-I expression and secretion in human hepatocyte- and enterocyte-like cells
Human apoA-I was overexpressed by transfection in BEL (显示 LHX2 ELISA试剂盒)-7402 hepatocytes and by an adenoviral vector in C57BL/6J mice fed a methionine choline-deficient diet. The overexpression of apoA-I in both models resulted in decreased reactive oxygen species and lipid peroxidation levels, as well as a reduced MAPK (显示 MAPK1 ELISA试剂盒) phosphorylation and decreased expression levels of c-Fos and COX-2 (显示 COX2 ELISA试剂盒).
The H10B sequence repeat of lipid-free human apoA-I is vital in HDL (显示 HSD11B1 ELISA试剂盒) formation.
Our results assign a novel role for 4F(apoA-I mimetic peptide ) as a modulator of the TICE pathway and suggest that the anti-inflammatory functions of 4F may be a partial consequence of the codependent intestinal transport of both 4F and cholesterol.
these data highlight a key role of the P2Y1 (显示 P2RY1 ELISA试剂盒)/PI3Kbeta axis in endothelial cell proliferation downstream of ecto (显示 TRIM33 ELISA试剂盒)-F1-ATPase (显示 DNAH8 ELISA试剂盒) activation by apoA-I. Pharmacological targeting of this pathway could represent a promising approach to enhance vascular endothelial protection.
apoA-I/ABCA1 (显示 ABCA1 ELISA试剂盒)-mediated cholesterol efflux without STAT3 (显示 STAT3 ELISA试剂盒) activation can reduce proinflammatory cytokine expression in macrophages.
a novel protective role for ApoA-I in colitis and CAC (显示 SLC25A20 ELISA试剂盒)
Preincubation of endothelial cells with apoA-I protected against the TNF-alpha (显示 TNF ELISA试剂盒)-induced inhibition of HTR (显示 F2R ELISA试剂盒)-8/SVneo (trophoblast) cell integration into endothelial (UtMVEC) networks. These data suggest that a healthy lipid profile may affect pregnancy outcomes by priming endothelial cells in preparation for trophoblast invasion.
Reductions in Dio1 (显示 DIO1 ELISA试剂盒) expression reduce the expression of ApoA-I in a 3,5,3'-triiodothyronine-/thyroid hormone (显示 PTH ELISA试剂盒) response element-independent manner.
apoA-1 deficiency generates changes in the bone cell precursor population that increase adipoblast, and decrease osteoblast production resulting in reduced bone mass and impaired bone quality
This study suggests that enhancement of macrophage cholesterol metabolism by PPARgammais not contributed by activating ABCA1 (显示 ABCA1 ELISA试剂盒) expression and ABCA1 (显示 ABCA1 ELISA试剂盒)-mediated cholesterol efflux to apoAI, which is not involved by CD36 (显示 CD36 ELISA试剂盒) expression either.
Mass spectrometry analysis of peptides derived from chemically crosslinked HDL (显示 HSD11B1 ELISA试剂盒)-SAA (显示 SAA1 ELISA试剂盒) particles detected multiple crosslinks between apoA1 and SAA (显示 SAA1 ELISA试剂盒), indicating close proximity (within 25 A) of these two proteins on the HDL (显示 HSD11B1 ELISA试剂盒) surface, providing a molecular and structural mechanism for the simultaneous binding of heparin to apoA1 and SAA (显示 SAA1 ELISA试剂盒).
results demonstrate that double deletion of Apoe (显示 APOE ELISA试剂盒) and Apoa1 ameliorated the amyloid pathology.
study suggests that apolipoprotein a1 can alleviate obesity related metabolic disease by inducing AMPK (显示 PRKAA1 ELISA试剂盒) dependent mitochondrial biogenesis.
Alterations in the Apo A (显示 APOA ELISA试剂盒)-I pattern is a good indicator of the presence and severity of infectious diseases in the pig.Lower overall amounts of Apo A (显示 APOA ELISA试剂盒)-I were observed in Salmonella typhimurium and Escherichia coli infections.
down-regulation of apolipoprotein A-I and A-IV messages in the liver may be mediated by interleukin 6 (显示 IL6 ELISA试剂盒) and tumor necrosis factor-alpha (显示 TNF ELISA试剂盒)
This study showed that apoA-I exerted protective effects against fatty liver disease in rabbits induced by a high-fat diet, possibly through its antioxidant actions.
The molar ratio ApoE (显示 APOE ELISA试剂盒)/ApoA-I is negatively correlated with the enzyme activity, and positively correlated with increases in the intima-media thickness of common carotid wall and cardiac dysfunction signs.
Binding of apoA-I to ectopic F(0)F(1) ATPase (显示 ATP5E ELISA试剂盒) triggers the generation of ADP, which via activation of the purinergic receptor P2Y (显示 P2RY1 ELISA试剂盒)(12) stimulates the uptake and transport of HDL (显示 HSD11B1 ELISA试剂盒) and initially lipid-free apoA-I by endothelial cells.
the model of a two-step process for the transendothelial transport of apoA-I in which apoA-I is initially lipidated by ABCA1 (显示 ABCA1 ELISA试剂盒) and then further processed by ABCA1 (显示 ABCA1 ELISA试剂盒)-independent mechanisms.
insulin (显示 INS ELISA试剂盒) secretion and tissue rejuvenation activities of WT-reconstituted high-density lipoproteins were nearly depleted by fructosylation, but V156K-rHDL did not lose its beneficial activity.
The NABB system using engineered zebrafish apo A-I is a native-like membrane mimetic system for G-protein-coupled receptors.
This gene encodes apolipoprotein A-I, which is the major protein component of high density lipoprotein (HDL) in plasma. The protein promotes cholesterol efflux from tissues to the liver for excretion, and it is a cofactor for lecithin cholesterolacyltransferase (LCAT) which is responsible for the formation of most plasma cholesteryl esters. This gene is closely linked with two other apolipoprotein genes on chromosome 11. Defects in this gene are associated with HDL deficiencies, including Tangier disease, and with systemic non-neuropathic amyloidosis.
, apolipoprotein A-I-like
, apolipoprotein A-I preproprotein
, apolipoprotein A1
, apolipoprotein A-1
, preproapolipoprotein A-I
, Apolipoprotein A1
, Apolipoprotein A-I