anti-Acyl-CoA Dehydrogenase, C-4 To C-12 Straight Chain (ACADM) 抗体产品概述

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anti-Acyl-CoA Dehydrogenase, C-4 To C-12 Straight Chain 抗体 (ACADM)
在www.antibodies-online.cn可供107 Acyl-CoA Dehydrogenase, C-4 To C-12 Straight Chain (ACADM) 抗体的22不同的供货商。 再加上,我们可以发Acyl-CoA Dehydrogenase, C-4 To C-12 Straight Chain 蛋白 (16)Acyl-CoA Dehydrogenase, C-4 To C-12 Straight Chain 试剂盒 (7)和数多这个蛋白质的别的产品。 总共143 Acyl-CoA Dehydrogenase, C-4 To C-12 Straight Chain产品已列进来了。
别名:
ACAD1, acaDM, AU018656, MCAD, MCADH

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引用最多的anti-Acyl-CoA Dehydrogenase, C-4 To C-12 Straight Chain 抗体

  1. Human Polyclonal ACADM Primary Antibody for IHC (p), IHC - ABIN249688 : Matsubara, Kraus, Yang-Feng, Francke, Rosenberg, Tanaka: Molecular cloning of cDNAs encoding rat and human medium-chain acyl-CoA dehydrogenase and assignment of the gene to human chromosome 1. in Proceedings of the National Academy of Sciences of the United States of America 1986 (PubMed)
    Show all 2 references for 249688

  2. Human Polyclonal ACADM Primary Antibody for ELISA, WB - ABIN559743 : Rennison, McElfresh, Okere, Patel, Foster, Patel, Stoll, Minkler, Fujioka, Hoit, Young, Hoppel, Chandler: Enhanced acyl-CoA dehydrogenase activity is associated with improved mitochondrial and contractile function in heart failure. in Cardiovascular research 2008 (PubMed)

  3. Human Polyclonal ACADM Primary Antibody for EIA, FACS - ABIN452704 : Ferreira, Orlandi, Oliveira, Malta, Caxito, Gomes, Valadares, Godard: A985G mutation incidence in the medium-chain acyl-CoA dehydrogenase (MCAD) gene in Brazil. in Genetics and molecular research : GMR 2009 (PubMed)

  4. Cow (Bovine) Polyclonal ACADM Primary Antibody for WB - ABIN2777594 : Parker: Binding of the human \electron transferring flavoprotein\" (ETF) to the medium chain acyl-CoA dehydrogenase (MCAD) involves an arginine and histidine residue." in Journal of enzyme inhibition and medicinal chemistry 2003 (PubMed)

  5. Cow (Bovine) Polyclonal ACADM Primary Antibody for WB - ABIN2777593 : Nichols, Saavedra-Matiz, Pass, Caggana: Novel mutations causing medium chain acyl-CoA dehydrogenase deficiency: under-representation of the common c.985 A > G mutation in the New York state population. in American journal of medical genetics. Part A 2008 (PubMed)

更多抗Acyl-CoA Dehydrogenase, C-4 To C-12 Straight Chain的相互作用对抗体

Human Acyl-CoA Dehydrogenase, C-4 To C-12 Straight Chain (ACADM) interaction partners

  1. Exclusively breastfed neonates with MCAD are at risk for early metabolic decompensation. As breastfeeding rates increase, close management of feeding difficulties is essential for all neonates awaiting newborn screening results

  2. The in silico structural changes in medium-chain acyl-CoA dehydrogenase (hMCAD) p.K329E variant protein affect the disturbed oligomeric profile, thermal stability, and conformational flexibility, with respect to the wild-type.

  3. LCHAD (显示 HADHA 抗体) and MCAD are differentially expressed in maternal and fetal tissues during normal late pregnancy, which may represent a metabolic adaptation in response to physiological maternal dyslipidemia during late pregnancy.

  4. Study determined three mutations (p.R53C, p.R281S and p.G362E) in MCAD protein predisposing for MCAD deficiency which seems to be unique to Japanese population.

  5. our study demonstrates that not all mutations identified in children with abnormal NBS (显示 NBN 抗体) profiles suggestive of MCAD deficiency result in a total loss in MCAD activity and function

  6. mutations in the ACADM gene lower the temperature threshold at which medium-chain acyl-CoA dehydrogenase deficiency loss-of-function occurs.

  7. Segregation studies in the Gypsy families showed that 93/123 relatives were carriers of the acyl-coenzyme A (显示 SOAT2 抗体) dehydrogenase G985 allele, suggesting its high prevalence in this ethnic group.

  8. Identify an ACADM founder mutation for MCADD in Saudi Arabian population.

  9. This supports that c.1161A>G is a functional SNP, which leads to higher MCAD expression, perhaps due to improved splicing. This study is a proof of principle that synonymous SNPs are not neutral.

  10. medium chain acyl-CoA dehydrogenase involve in the metabolism of phenylbutyrate.

Cow (Bovine) Acyl-CoA Dehydrogenase, C-4 To C-12 Straight Chain (ACADM) interaction partners

  1. ACADM and ALDH2 (显示 ALDH2 抗体) were predicted to be the target genes of miR (显示 MYLIP 抗体)-224

Pig (Porcine) Acyl-CoA Dehydrogenase, C-4 To C-12 Straight Chain (ACADM) interaction partners

  1. Investigation of ACADM in relation to fat deposition traits.

  2. Investigation of structure of enzyme (from kidney) complexed with FAD analogs (e.g., 8-NH2-FAD) and acyl-CoA (e.g., octanoyl-CoA).

Mouse (Murine) Acyl-CoA Dehydrogenase, C-4 To C-12 Straight Chain (ACADM) interaction partners

  1. the transcriptional regulatory circuits involved in the control of MCAD gene expression under hypoxic conditions are modulated by upstream factors that are sensitive to the levels of oxygen

  2. MCAD is reduced in liver, heart & kidney in lipopolysaccharide-induced acute phase response; binding liver nuclear extracts to ERRalpha (显示 ESRRA 抗体) response element found in promoter region of MCAD was decreased during APR (显示 PMAIP1 抗体), suggesting less transcription of MCAD

  3. The MCAD-/- mice developed an organic aciduria and fatty liver, and showed profound cold intolerance at 4 degrees C with prior fasting.

  4. MCAD deficiency in mice leads to specific changes in hepatic carbohydrate management on exposure to metabolic stress.

  5. A high-fat diet increases adiposity but maintains mitochondrial oxidative enzymes (MCAD/citrate synthase (显示 CS 抗体)) without affecting development of heart failure with pressure overload.

Acyl-CoA Dehydrogenase, C-4 To C-12 Straight Chain (ACADM) 抗原简介

Antigen Summary

This gene encodes the medium-chain specific (C4 to C12 straight chain) acyl-Coenzyme A dehydrogenase. The homotetramer enzyme catalyzes the initial step of the mitochondrial fatty acid beta-oxidation pathway. Defects in this gene cause medium-chain acyl-CoA dehydrogenase deficiency, a disease characterized by hepatic dysfunction, fasting hypoglycemia, and encephalopathy, which can result in infantile death. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Alternative names and synonyms associated with Acyl-CoA Dehydrogenase, C-4 To C-12 Straight Chain (ACADM)

  • acyl-CoA dehydrogenase (acd) 抗体
  • acyl-CoA dehydrogenase, C-4 to C-12 straight chain (ACADM) 抗体
  • acyl-CoA dehydrogenase, C-4 to C-12 straight chain (acadm) 抗体
  • acyl-CoA dehydrogenase, C-4 to C-12 straight chain (Acadm) 抗体
  • acyl-Coenzyme A dehydrogenase, medium chain (Acadm) 抗体
  • ACAD1 抗体
  • acaDM 抗体
  • AU018656 抗体
  • MCAD 抗体
  • MCADH 抗体

Protein level used designations for ACADM

acyl-CoA dehydrogenase, C-4 to C-12 straight chain , medium-chain acyl-CoA dehydrogenase , acyl-Coenzyme A dehydrogenase, C-4 to C-12 straight chain , medium-chain specific acyl-CoA dehydrogenase, mitochondrial-like , medium-chain specific acyl-CoA dehydrogenase, mitochondrial , C-4 to C-12 straight chain acyl-coenzyme A dehydrogenase , MCAD , acyl-coenzyme A dehydrogenase, C-4 to C-12 straight chain , Acyl-Coenzyme A dehydrogenase C-4 to C-12 straight-chain , Acyl-Coenzyme A dehydrogenase, C-4 to C-12 straight-chain , acyl-Coenzyme A dehydrogenase, medium chain , acyl-Coenzyme A dehydrogenase, C-4 to C-12 straight chain, nuclear gene encoding mitochondrial protein

GENE ID SPECIES
8792410 Azospirillum sp. B510
8793572 Azospirillum sp. B510
100347504 Oryctolagus cuniculus
446467 Xenopus laevis
705168 Macaca mulatta
100391471 Callithrix jacchus
100600902 Nomascus leucogenys
34 Homo sapiens
505968 Bos taurus
24158 Rattus norvegicus
397104 Sus scrofa
490207 Canis lupus familiaris
469356 Pan troglodytes
11364 Mus musculus
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