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IL21 Receptor 抗体

(Interleukin 21 Receptor (IL21R))
The protein encoded by this gene is a cytokine receptor for interleukin 21 (IL21). It belongs to the type I cytokine receptors, and has been shown to form a heterodimeric receptor complex with the common gamma-chain, a receptor subunit also shared by the receptors for interleukin 2, 4, 7, 9, and 15. This receptor transduces the growth promoting signal of IL21, and is important for the proliferation and differentiation of T cells, B cells, and natural killer (NK) cells. The ligand binding of this receptor leads to the activation of multiple downstream signaling molecules, including JAK1, JAK3, STAT1, and STAT3. Knockout studies of a similar gene in mouse suggest a role for this gene in regulating immunoglobulin production. Three alternatively spliced transcript variants have been described. [provided by RefSeq, Jul 2010].
IL21 Receptor 抗体  (AA 20-232) IL21 Receptor 抗体  (AA 20-232) IL21 Receptor 抗体 (AA 20-232) (ABIN7193230)

IL21R 适用: 人 WB, ELISA, IHC, FACS, ICC, Neut 宿主: 小鼠 Monoclonal 8H10G4D12 unconjugated

IL21 Receptor 抗体  (AA 20-240) IL21 Receptor 抗体  (AA 20-240) IL21 Receptor 抗体 (AA 20-240) (ABIN7156852)

IL21R 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated

IL21 Receptor 抗体  (AA 97-111) IL21 Receptor 抗体  (AA 97-111) IL21 Receptor 抗体 (AA 97-111) (ABIN541415)

IL21R 适用: 人, 小鼠, 大鼠 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated

IL21 Receptor 抗体 by 适用

Find IL21 Receptor 抗体 for a variety of species such as anti-Human IL21 Receptor, anti-Mouse IL21 Receptor, anti-Rat IL21 Receptor. The species listed below are among those available. Click on a link to go to the corresponding products.

IL21 Receptor 抗体 by 应用范围

Find IL21 Receptor 抗体 validated for a specific application such as WB, ELISA, IF (cc), IF (p). Some of the available applications are listed below. Click on a link to go to the corresponding products.

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Find IL21 Receptor 抗体 with a specific epitope. The epitopes listed below are among those available. Click on a link to go to the corresponding products.

IL21 Receptor 抗体 by 克隆形成能力

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Find IL21 Receptor 抗体 with a specific conjugate such as Alexa Fluor 488, Alexa Fluor 555, Alexa Fluor 594. The conjugates listed below are among those available. Click on a link to go to the corresponding products.

IL21 Receptor 抗体 by Fragment

Find IL21 Receptor 抗体 with a specific Fragment. The Fragment listed below are among those available. Click on a link to go to the corresponding products.

Popular IL21 Receptor 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, ELISA, IHC, FACS, ICC, Neut
Validations
  • (4)
Cat. No. ABIN7193230
Quantity 0.1 mg
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, IHC
Validations
  • (3)
Cat. No. ABIN7156852
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application WB, IHC (p)
Validations
  • (3)
  • (2)
Cat. No. ABIN541415
Quantity 100 μg
Datasheet Datasheet
Reactivity Mouse
Application WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro)
Validations
  • (1)
  • (1)
Cat. No. ABIN748148
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application ELISA, IHC
Validations
  • (1)
Cat. No. ABIN7156851
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB
Validations
  • (1)
Cat. No. ABIN6242400
Quantity 200 μL
Datasheet Datasheet
Reactivity Human
Application ELISA, IHC (p)
Validations
  • (1)
Cat. No. ABIN2474983
Quantity 0.1 mg
Datasheet Datasheet
Reactivity Human, Monkey
Application WB, ELISA
Validations
  • (1)
Cat. No. ABIN208550
Quantity 0.1 mg
Datasheet Datasheet
Reactivity Human
Application WB, ELISA
Validations
  • (1)
Cat. No. ABIN537515
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB, IHC, ICC
Validations
  • (2)
Cat. No. ABIN1868630
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application WB, ELISA, IHC
Validations
  • (2)
Cat. No. ABIN1030836
Quantity 0.1 mg
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application WB, IHC (p), EIA
Validations
  • (2)
Cat. No. ABIN499988
Quantity 0.1 mg
Datasheet Datasheet
Reactivity Mouse
Application WB, ELISA, IHC (p), IHC (fro)
Validations
Cat. No. ABIN748150
Quantity 100 μL
Datasheet Datasheet
Reactivity Mouse
Application WB, IF (cc), IF (p)
Validations
Cat. No. ABIN902339
Quantity 100 μL
Datasheet Datasheet
Reactivity Mouse
Application WB, IF (cc), IF (p)
Validations
Cat. No. ABIN902337
Quantity 100 μL
Datasheet Datasheet

Latest Publications for our IL21 Receptor 抗体

Sekiguchi, Nomoto, Nagata, Kiyota, Fukuda, Yamada, Takezako, Kobayashi: "Gene Expression Profile Signature of Aggressive Waldenström Macroglobulinemia with Chromosome 6q Deletion." in: BioMed research international, Vol. 2018, pp. 6728128, (2019) (PubMed).

Linnebacher, Mayer, Marnet, Bergmann, Herpel, Revia, Yin, Liu, Hackert, Giese, Herr, Gaida: "Interleukin 21 Receptor/Ligand Interaction Is Linked to Disease Progression in Pancreatic Cancer." in: Cells, Vol. 8, Issue 9, (2019) (PubMed).

Zhang, Kiapour, Kapoor, Khan, Thamilarasan, Tao, Cohen, Miller, Sobel, Markovic-Plese: "IL-11 Induces Encephalitogenic Th17 Cells in Multiple Sclerosis and Experimental Autoimmune Encephalomyelitis." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 203, Issue 5, pp. 1142-1150, (2019) (PubMed).

Dinesh, Rasool et al.: "Berberine inhibits IL-21/IL-21R mediated inflammatory proliferation of fibroblast-like synoviocytes through the attenuation of PI3K/Akt signaling pathway and ameliorates IL-21 mediated ..." in: Cytokine, Vol. 106, pp. 54-66, (2018) (PubMed).

Guan, Wang, Meng, Shi, Jiang, Xiao, Shi, Xu, Zhang: "Increased IL-21/IL-21R expression and its proinflammatory effects in autoimmune thyroid disease." in: Cytokine, Vol. 72, Issue 2, pp. 160-5, (2015) (PubMed).

Zhang, Tao, Chopra, Dujmovic-Basuroski, Jin, Tang, Drulovic, Markovic-Plese: "IL-11 Induces Th17 Cell Responses in Patients with Early Relapsing-Remitting Multiple Sclerosis." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 194, Issue 11, pp. 5139-49, (2015) (PubMed).

Kaltenmeier, Gawanbacht, Beyer, Lindner, Trzaska, van der Merwe, Härter, Grüner, Fabricius, Lotfi, Schwarz, Schütz, Hönig, Schulz, Kern, Bommer, Schrezenmeier, Kirchhoff, Jahrsdörfer: "CD4+ T cell-derived IL-21 and deprivation of CD40 signaling favor the in vivo development of granzyme B-expressing regulatory B cells in HIV patients." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 194, Issue 8, pp. 3768-77, (2015) (PubMed).

Biswas, Gupta, Stirzaker, Kumar, Jessberger, Lu, Bhagat, Pernis: "Dual regulation of IRF4 function in T and B cells is required for the coordination of T-B cell interactions and the prevention of autoimmunity." in: The Journal of experimental medicine, Vol. 209, Issue 3, pp. 581-96, (2012) (PubMed).

Liu, Yang, Ma, Wang, Huang, Zhang, Chen, Wu: "Interleukin-21 induces the differentiation of human Tc22 cells via phosphorylation of signal transducers and activators of transcription." in: Immunology, Vol. 132, Issue 4, pp. 540-8, (2011) (PubMed).

Sarra, Caruso, Cupi, Monteleone, Stolfi, Campione, Diluvio, Mazzotta, Botti, Chimenti, Costanzo, MacDonald, Pallone, Monteleone: "IL-21 promotes skin recruitment of CD4(+) cells and drives IFN-?-dependent epidermal hyperplasia." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 186, Issue 9, pp. 5435-42, (2011) (PubMed).

Aliases for IL21 Receptor 抗体

interleukin 21 receptor (IL21R) 抗体
interleukin 21 receptor, tandem duplicate 1 (il21r.1) 抗体
interleukin 21 receptor (Il21r) 抗体
CD360 抗体
il-21ra.a 抗体
IL21R 抗体
NILR 抗体
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