anti-GNAT1 (GNAT1) 抗体产品概述

Full name:
anti-Guanine Nucleotide Binding Protein (G Protein), alpha Transducing Activity Polypeptide 1 抗体 (GNAT1)
在www.antibodies-online.cn可供45 Guanine Nucleotide Binding Protein (G Protein), alpha Transducing Activity Polypeptide 1 (GNAT1) 抗体的13不同的供货商。 再加上,我们可以发GNAT1 蛋白 (5)和数多这个蛋白质的别的产品。 总共55 GNAT1产品已列进来了。
别名:
CSNBAD3, GBT1, Gnat-1, GNAT1, GNATR, Ird1, Ird2, irdc, irdr, Tralpha, transducin, wu:fk56e06
列出全部抗体 基因 基因ID UniProt
GNAT1 2779 P11488
GNAT1 363143  
GNAT1 14685 P20612

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引用最多的anti-GNAT1 抗体

  1. Human Polyclonal GNAT1 Primary Antibody for FACS, IHC (p) - ABIN955309 : Szabo, Kreienkamp, Rosenberg, Gal: p.Gln200Glu, a putative constitutively active mutant of rod alpha-transducin (GNAT1) in autosomal dominant congenital stationary night blindness. in Human mutation 2007 (PubMed)
    Show all 4 references for 955309

  2. Human Polyclonal GNAT1 Primary Antibody for ELISA, WB - ABIN1534969 : Lerea, Bunt-Milam, Hurley: Alpha transducin is present in blue-, green-, and red-sensitive cone photoreceptors in the human retina. in Neuron 1990 (PubMed)

更多抗GNAT1的相互作用对抗体

Cow (Bovine) Guanine Nucleotide Binding Protein (G Protein), alpha Transducing Activity Polypeptide 1 (GNAT1) interaction partners

  1. Data suggest that a hetero-multimer complex forms between light-activated rhodopsin (显示 RHO 抗体) and light-activated heterotrimeric transducin (T-alpha-1, Gnb1 (显示 GNB1 抗体), Gngt1 (显示 GNGT1 抗体)); the stoichiometry is 1:1 rhodopsin:transducin. The complex appears to form on native rod outer segment membranes upon light activation.

  2. These results indicated that efficient Gt activation by rhodopsin (显示 RHO 抗体), resulting from an optimized active state of rhodopsin (显示 RHO 抗体), is one of the causes of the high amplification efficiency of rods.

Human Guanine Nucleotide Binding Protein (G Protein), alpha Transducing Activity Polypeptide 1 (GNAT1) interaction partners

  1. These data suggest that some truncating GNAT1 variants can indeed cause a recessive, mild, late-onset retinal degeneration in human beings rather than just stationary night-blindness as reported previously.

  2. Three candidate tumor-suppressor genes, SEMA3B (显示 SEMA3B 抗体), AXUD1 (显示 CSRNP1 抗体) and GNAT1 may be involved in oral squamous cell carcinoma.

  3. These data suggest that a homozygous missense mutation in GNAT1 is associated with autosomal recessive stationary night blindness.

  4. Expression of GNAT1 gene is down-regulated or absent in nasopharyngeal carcinoma tissues.

Mouse (Murine) Guanine Nucleotide Binding Protein (G Protein), alpha Transducing Activity Polypeptide 1 (GNAT1) interaction partners

  1. Data suggest light reduces oxygen consumption rate (OCR) of retina; light does not affect OCR in retinas of Gnat1-/- knockout mice (phototransduction disabled). Light reduces cGMP in retina; light does not alter cGMP in Gnat1-/- plus Gnat2 (显示 GNAT2 抗体)-/- retina.

  2. Biochemical changes, including reduced transducin protein levels and enhanced transducin GTPase (显示 RACGAP1 抗体) activity, explain the shift in light intensity threshold for Galphat1 translocation in Rs1 (显示 RS1 抗体)-knockout mice.

  3. The results from shaker1 and whirler (显示 DFNB31 抗体) mice suggest that defective transducin translocation may be functionally related to light-induced degeneration.

  4. ectopically expressed cTalpha (显示 PCYT1A 抗体) 1) forms a heterotrimeric complex with rod Gbeta (显示 SUCLG2 抗体)(1)gamma(1), and substitutes equally for rTalpha in generating photoresponses initiated by either rhodopsin (显示 RHO 抗体) or S-cone opsin (显示 RHO 抗体)

  5. Oligomerization incompetent retinal degeneration slow (显示 PRPH2 抗体) is associated with mislocalization of cone opsins and cone transducin.

  6. Data show that visual responses in TKO (显示 MRPS12 抗体) mice extend beyond the retina to encompass the lateral margins of the lateral geniculate nucleus and components of the visual cortex.

  7. Thus our results showed that IRD1 and IRD2 mice harbor a nonsense mutation in the Gnat1 gene, resulting in the absence or suppressed expression of the Tralpha protein, which is the likely cause of rod dysfunction in both mutants.

  8. alpha-transducin can function in taste receptor cells and transduce some taste cell responses

  9. data suggest that phosducin (显示 PDC 抗体) action is based on the reduction of transducin affinity to the membranes of rod outer segments, achieved by keeping the transducin beta gamma subunits apart from the alpha subunit (显示 POLG 抗体).

  10. Alpha-transducin played no role in regulating adaptive response to light. Degeneration does not require transducin-mediated signaling.

GNAT1 抗原简介

Antigen Summary

Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems. Transducin is an amplifier and one of the transducers of a visual impulse that performs the coupling between rhodopsin and cGMP-phosphodiesterase.

Alternative names and synonyms associated with GNAT1

  • guanine nucleotide binding protein (G protein), alpha transducing activity polypeptide 1 (GNAT1) 抗体
  • guanine nucleotide binding protein (G protein), alpha transducing activity polypeptide 1 (gnat1) 抗体
  • guanine nucleotide binding protein (G protein), alpha transducing activity polypeptide 1 (Gnat1) 抗体
  • guanine nucleotide binding protein, alpha transducing 1 (Gnat1) 抗体
  • CSNBAD3 抗体
  • GBT1 抗体
  • Gnat-1 抗体
  • GNAT1 抗体
  • GNATR 抗体
  • Ird1 抗体
  • Ird2 抗体
  • irdc 抗体
  • irdr 抗体
  • Tralpha 抗体
  • transducin 抗体
  • wu:fk56e06 抗体

Protein level used designations for GNAT1

guanine nucleotide-binding protein G(t) subunit alpha-1 , rod-type transducin alpha subunit , guanine nucleotide binding protein (G protein), alpha transducing activity polypeptide 1 , guanine nucleotide binding protein, alpha transducing activity polypeptide 1 , guanine nucleotide-binding protein G(t) subunit alpha-1-like , transducin alpha-1 chain , guanine nucleotide-binding protein G(T), alpha-1 subunit , transducin, rod-specific , guanine nucleotide binding protein (G protein), alpha transducing 1 , guanine nucleotide binding protein, alpha transducing 1 , Galpha t1 , fk56e06 , rod transducin alpha subunit , transducin alpha (rod) , rod photoreceptor transducin alpha 1 subunit , transducin alpha subunit GNAT1

GENE ID SPECIES
395426 Gallus gallus
703881 Macaca mulatta
744813 Pan troglodytes
100124843 Xenopus (Silurana) tropicalis
100457419 Pongo abelii
281794 Bos taurus
2779 Homo sapiens
363143 Rattus norvegicus
140428 Danio rerio
403613 Canis lupus familiaris
444825 Xenopus laevis
14685 Mus musculus
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