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抗Human ARHGAP5 抗体:
抗Mouse (Murine) ARHGAP5 抗体:
抗Rat (Rattus) ARHGAP5 抗体:
Dog (Canine) Monoclonal ARHGAP5 Primary Antibody for IF, WB - ABIN968611
Burbelo, Finegold, Kozak, Yamada, Takami: Cloning, genomic organization and chromosomal assignment of the mouse p190-B gene. in Biochimica et biophysica acta 1999
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Dog (Canine) Monoclonal ARHGAP5 Primary Antibody for IF, WB - ABIN968612
Burbelo, Miyamoto, Utani, Brill, Yamada, Hall, Yamada: p190-B, a new member of the Rho GAP family, and Rho are induced to cluster after integrin cross-linking. in The Journal of biological chemistry 1996
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Kazrin (显示 KAZ 抗体) interacts with ARVCF (显示 ARVCF 抗体)-catenin, spectrin and p190B RhoGAP (显示 ARHGAP1 抗体), and modulates RhoA (显示 RHOA 抗体) activity.
only collagen-IV (显示 COL4 抗体) elicits the formation of proteolytically active podosomes through a mechanism involving increased Src (显示 SRC 抗体) phosphorylation, p190RhoGAP (显示 GRLF1 抗体)-B (also known as ARHGAP5) relocalisation and MT1-MMP (显示 MMP14 抗体) (also known as MMP14 (显示 MMP14 抗体)) cell surface exposure at podosome sites.
Brazilian Amerindian ancestry compared to Asian, European, and African Genomes.SNPs within or proximal to CIITA (显示 CIITA 抗体) (rs6498115), SMC6 (显示 SMC6 抗体) (rs1834619), and KLHL29 (rs2288697) were most differentiated in the Amerindian-specific branch. SNPs in ADAMTS9 (显示 ADAMTS9 抗体) (rs7631391), DOCK2 (显示 DOCK2 抗体) (rs77594147), SLC28A1 (rs28649017), ARHGAP5 (rs7151991), and CIITA (显示 CIITA 抗体) (rs45601437) in the Asian comparison.
This newly identified miR (显示 MLXIP 抗体)-744/ARHGAP5 pathway provides further insight into the progression and metastasis of NPC (显示 NPC1 抗体) and indicates potential novel therapeutic targets for NPC (显示 NPC1 抗体).
Ectopic expression of p190B suppressed the miR (显示 MLXIP 抗体)-494-induced EGFR (显示 EGFR 抗体) upregulation.
The expression level of miR (显示 MLXIP 抗体)-486-5p was inversely correlated with that of ARHGAP5.
RhoA (显示 RHOA 抗体) is down-regulated at cell-cell contacts via p190RhoGAP (显示 GRLF1 抗体)-B in response to tensional homeostasis.
Data indicate a role for p120-catenin (显示 CTNND1 抗体) (amino acids 820-843) domain in the p120 (显示 HNRNPU 抗体)-catenin.p190RhoGAP signaling complex assembly and membrane targeting.
A cell cycle-regulated reduction in endogenous p190 (显示 CNTNAP1 抗体) levels is linked to completion of cytokinesis and generation of viable cell progeny.
precise control of p190-B Rho GTPase-activating protein (显示 STARD13 抗体) activity is critical for normal branching morphogenesis during mammary gland development
ARHGAP5 (the gene encoding p190-B RhoGAP (显示 ARHGAP1 抗体)) is a probable target for the amplification at 14q12, and p190-B RhoGAP (显示 ARHGAP1 抗体) promotes cells spreading and migration by negatively regulating RhoA (显示 RHOA 抗体) activity in Huh-7 hepatocellular carcinoma cells
Loss of p190-B expression is associated with defective hematopoiesis.
Rac1 activity and oxidative stress are elevated in tumors expressing exogenous p190B suggesting that p190B may promote tumorigenesis through a Rac1/ROS (显示 ROS1 抗体) dependent mechanism.
p190B haploinsufficiency in the epithelium inhibits MMTV-Neu tumor initiation. p190B deficiency in the vasculature is responsible, in part, for the inhibition of MMTV-Neu tumor progression.
Mice lacking the Rho-inhibitory protein, p190-B RhoGAP (显示 ARHGAP1 抗体), are 30% reduced in size and exhibit developmental defects strikingly similar to those seen in mice lacking the CREB (显示 CREB1 抗体) transcription factor.
Results suggest that p190-B regulates ductal morphogenesis, at least in part, by modulating the IGF signaling axis
precise control of p190-B Rho GTPase-activating protein (显示 ARHGAP32 抗体) activity is critical for normal branching morphogenesis during mammary gland development
IGF signaling through p190-B and IRS (显示 IARS 抗体) proteins is critical for mammary bud formation and ensuing epithelial-mesenchymal interactions necessary to sustain mammary bud morphogenesis
Loss of the Rho GTPase activating protein p190-B enhances hematopoietic stem cell engraftment potential.
Rho GTPase activating protein 5 negatively regulates RHO GTPases, a family which may mediate cytoskeleton changes by stimulating the hydrolysis of bound GTP. Two transcript variants encoding different isoforms have been found for this gene.
Rho GTPase activating protein 5
, chimerin (chimaerin) 1-like
, rho GTPase-activating protein 5-like
, growth factor independent 2
, p100 RasGAP-associated p105 protein
, p105 RhoGAP
, rho GTPase-activating protein 5
, rho-type GTPase-activating protein 5