anti-EGR1 (EGR1) 抗体产品概述

Full name:
anti-Early Growth Response 1 抗体 (EGR1)
在www.antibodies-online.cn可供132 Early Growth Response 1 (EGR1) 抗体的24不同的供货商。 再加上,我们可以发EGR1 试剂盒 (45)EGR1 蛋白 (19)和数多这个蛋白质的别的产品。 总共204 EGR1产品已列进来了。
别名:
A530045N19Rik, at225, egr, egr-1, EGR-1-A, EGR1, ETR103, g0s30, Krox-1, krox-24, krox24, Ngf1, NGF1-A, Ngfi, ngfi-a, NGFIA, tis8, wu:fj64b05, wu:fq25f01, Xegr-1, zenk, Zfp-6, zif-268, Zif268, znf225

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引用最多的anti-EGR1 抗体

  1. Cow (Bovine) Polyclonal EGR1 Primary Antibody for IHC, WB - ABIN2779517 : Yu, de Belle, Liang, Adamson: Coactivating factors p300 and CBP are transcriptionally crossregulated by Egr1 in prostate cells, leading to divergent responses. in Molecular cell 2004 (PubMed)
    Show all 8 references for 2779517

  2. Human Monoclonal EGR1 Primary Antibody for IF, WB - ABIN393945 : Kim, Jeong, Jeong, Kim, Lee, Shin, Kye, Son: Cigarette smoke-induced Egr-1 represses T beta R-II expression in human skin dermal fibroblasts. in Toxicology 2010 (PubMed)
    Show all 5 references for 393945

  3. Human Monoclonal EGR1 Primary Antibody for WB - ABIN394244 : Xu, Toure, Qu, Lin, Song, Shen, Rosario, Garcia, Schmidt, Yan: Advanced glycation end product (AGE)-receptor for AGE (RAGE) signaling and up-regulation of Egr-1 in hypoxic macrophages. in The Journal of biological chemistry 2010 (PubMed)
    Show all 5 references for 394244

  4. Human Monoclonal EGR1 Primary Antibody for ELISA, WB - ABIN969092 : Chan, Lee, Ho, Wong, Lam, Tang, Chan, Abdullah, Wong, Lam: High-level expression of early growth response-1 and association of polymorphism with total IgE and atopy in allergic rhinitis adults. in Clinica chimica acta; international journal of clinical chemistry 2009 (PubMed)
    Show all 2 references for 969092

  5. Human Polyclonal EGR1 Primary Antibody for FACS, IF - ABIN389442 : Zhang, Chen, Wang, Guang, Han, Zhang, Tan, Gu: EGR1 decreases the malignancy of human non-small cell lung carcinoma by regulating KRT18 expression. in Scientific reports 2014 (PubMed)
    Show all 2 references for 389442

  6. Cow (Bovine) Polyclonal EGR1 Primary Antibody for WB - ABIN2774222 : Akutagawa, Nishi, Kyo, Terauchi, Yamazawa, Higuma, Inoue, Isaka: Early growth response-1 mediates downregulation of telomerase in cervical cancer. in Cancer science 2008 (PubMed)

  7. Cow (Bovine) Polyclonal EGR1 Primary Antibody for IHC, WB - ABIN2779828 : Schnell, Zoller, Patel, Williams, Kersh: Early growth response gene 1 provides negative feedback to inhibit entry of progenitor cells into the thymus. in Journal of immunology (Baltimore, Md. : 1950) 2006 (PubMed)

更多抗EGR1的相互作用对抗体

Pig (Porcine) Early Growth Response 1 (EGR1) interaction partners

  1. Egr-1 silencing through intracoronary delivery of a targeting DNAzyme at the time of reperfusion following acute myocardial ischemia decreases myocardial inflammation and apoptosis leading to improved cardiac function.

  2. Intracoronary delivery of DNAzymes targeting human EGR-1 reduces infarct size following myocardial ischaemia reperfusion.

  3. Data suggest that Egr-1 protein levels may be tightly regulated in an attempt to diminish neurotoxicity or to enhance plasticity in newborn animals.

Human Early Growth Response 1 (EGR1) interaction partners

  1. Finally, the authors show that EGFR (显示 EGFR 抗体)-ERK1/2 (显示 MAPK1/3 抗体) and beta1-integrin signaling are the main pathways used for bacteria-mediated EGR1 upregulation.

  2. Early growth response (Egr)-1 is essential for fibrotic responses to Transforming growth factor (TGF)-beta (显示 TGFB1 抗体). Egr-1 mediates TGF-beta1 (显示 TGFB1 抗体)-induced COL1A1 (显示 COL1A1 抗体) and COL1A2 (显示 COL1A2 抗体) mRNA expression and acid-soluble collagen production in buccal mucosal fibroblasts (BMFs).The epigallocatechin-3-gallate (EGCG) can block TGF-beta1 (显示 TGFB1 抗体)-induced collagen production by attenuating Egr-1 expression in BMFs.

  3. Along with the reduction of ovarian cancer-2/disabled homolog 2 (DOC-2 (显示 DAB2 抗体)/DAB2) interactive protein (DAB2IP (显示 DAB2IP 抗体)) expression, EGR-1 gene was upregulated in FI-treated cells. On the other hand, downregulation of EGR-1 gene expression sensitized radioresistant cells to IR accompanied by DAB2IP (显示 DAB2IP 抗体) overexpression and STAT3 (显示 STAT3 抗体) inactivation. In addition, NF-kappaB (显示 NFKB1 抗体) inhibitor, BAY11-7082 enhanced resistant cells' radiosensitivity and chemos...

  4. ROS (显示 ROS1 抗体) activation of the MAPK (ERK (显示 MAPK1 抗体)-1 (显示 MAPK3 抗体)/2)/Egr-1 pathway is a main player in the regulatory mechanism for cigarette smoke extract-induced PlGF (显示 PGF 抗体) production. Antioxidants could partly abolish these effects.

  5. adipose tissue-derived mesenchymal stem cells (AT-MSCs) from diabetic patients may contribute to microvascular damage and delay wound healing through the overexpression of EGR-1.

  6. KLF12 (显示 KLF12 抗体) promotes tumor growth by directly activating early growth response protein 1 (EGR1). The levels of KLF12 (显示 KLF12 抗体) and EGR1 correlate synergistically with a poor prognosis. These results indicate that KLF12 (显示 KLF12 抗体) likely plays an important role in CRC (显示 CALR 抗体) and could serve as a potential prognostic marker and therapeutic target.

  7. Shikonin induces apoptosis in some lung cancer cells via activation of FOXO3a (显示 FOXO3 抗体)/EGR1/SIRT1 (显示 SIRT1 抗体) signaling, and AKT (显示 AKT1 抗体) and p300 (显示 EP300 抗体) negatively regulate this process via Bim (显示 BCL2L11 抗体) upregulation.

  8. Inhibition of mTORC1-mediated 4EBP1 (显示 EIF4EBP1 抗体) phosphorylation leads to decreased expression of c-MYC (显示 MYC 抗体) and subsequent upregulation of the proapoptotic BCL2 (显示 BCL2 抗体) family member PUMA (显示 BBC3 抗体), whereas inhibition of mTORC2 (显示 CRTC2 抗体) results in nuclear factor-kappaB-mediated expression of the Early Growth Response 1 (EGR1) gene, which encodes a transcription factor that binds and transactivates the proapoptotic BCL2L11 (显示 BCL2L11 抗体) locus encoding BIM (显示 BCL2L11 抗体).

  9. Conversely, siRNA-mediated Klotho (显示 KL 抗体) silencing up-regulated Egr-1, FN, and Col (显示 HDAC1 抗体) I expression and the p-Smad3/Smad3 (显示 SMAD3 抗体) ratio. Moreover, the effects of si-Klotho (显示 KL 抗体) on Egr-1 expression were abolished by the TGF-beta1 (显示 TGFB1 抗体) inhibitor SB-431542. Klotho (显示 KL 抗体) overexpression can prevent mesangial ECM (显示 MMRN1 抗体) production in high-glucose-treated human MCs (显示 SMCP 抗体), an effect that has been partially attributed to Egr-1 down-regulation facilitated by TGF-beta1 (显示 TGFB1 抗体)/Smad3 (显示 SMAD3 抗体) s...

  10. ZHX1 (显示 ZHX1 抗体) was found to play essential roles in the proliferation, migration, and invasion of cholangiocarcinoma cells, and its effect on the proliferation was mediated partially through EGR1.

Cow (Bovine) Early Growth Response 1 (EGR1) interaction partners

  1. Chronic hypoxia induces Egr-1 via activation of ERK1/2 (显示 MAPK1/3 抗体) and contributes to pulmonary vascular remodeling.

  2. The authors conclude that Egr-1 protein expression is very sensitive to upregulation by hypoxia in pulmonary artery adventitial fibroblasts and that it plays an important role in the autonomous growth phenotype induced by hypoxia in these cells.

  3. EGR-1's expression prior to ovulation and its stimulating effect on the expression of genes known to be involved in prostaglandin biosynthesis pathway, suggest its potential involvement in the regulation of preovulatory events in cattle.

Mouse (Murine) Early Growth Response 1 (EGR1) interaction partners

  1. Herein, we report that silencing of Egr-1 in the hippocampus by shRNA reduces tau phosphorylation, lowers amyloid-beta (Abeta (显示 APP 抗体)) pathology, and improves cognition in the 3xTg-Alzheimer disease mouse model.

  2. Egr-1 is a novel regulator of drebrin (显示 DBN1 抗体) expression, which is linked to changes in dendritic spine density

  3. In the present study, we have investigated the contribution of element C to Krox20 (显示 EGR2 抗体) expression, as it was the only characterized initiator element with an activity in r3. Using a conditional knock-out mutation of element C, we show that, unexpectedly, this element is not necessary for Krox20 (显示 EGR2 抗体) initial expression in r3.

  4. HAS2 (显示 HAS2 抗体)-produced hyaluronan is required for CD44V6 and TGFbetaRI co-localization and subsequent CD44V6/ERK1 (显示 MAPK3 抗体)/EGR1 signaling. These results demonstrate a novel positive-feedback loop that links the myofibroblast phenotype to TGFbeta1 (显示 TGFB1 抗体)-stimulated CD44V6/ERK (显示 EPHB2 抗体)/EGR1 signaling.

  5. Egr1 expression is sensitive to mechanical signals in tendon cells.

  6. age-related up-regulation of EGR1 promotes granulosa cell apoptosis in follicle atresia during ovarian aging.

  7. data indicate that Egr-1 promotes Abeta (显示 APP 抗体) synthesis via transcriptional activation of BACE-1 (显示 BACE 抗体) and suggest that Egr-1 plays role in activation of BACE-1 (显示 BACE 抗体) and acceleration of Abeta (显示 APP 抗体) synthesis in AD brain.

  8. EGR1, an early growth response factor, is a critical transcription factor that regulates the hepatic clock circuit.

  9. EGR1(-/-) mouse embryonic fibroblasts demonstrated lower susceptibility to Venezuelan equine encephalitis virus-induced cell death than isogenic wild-type fibroblasts, indicating that EGR1 modulates proapoptotic pathways following virus infection.

  10. The levels of B23 (显示 NPM1 抗体) expression are directly regulated by EGR1.

Zebrafish Early Growth Response 1 (EGR1) interaction partners

  1. egr1 colocalizes with tyrosine hydroxylase (显示 TH 抗体) in the olfactory bulb throughout brain development.

  2. successive induction of the transcription factors Runx3, Egr1 and Sox9b constitutes a regulatory cascade that controls expression of Follistatin A in pharyngeal endoderm, the latter modulating BMP signaling in developing cranial cartilage in zebrafish

  3. The cDNA coding for zebrafish Egr1 was obtained and its expression pattern was examined during zebrafish embryogenesis using whole-mount in situ hybridization

  4. Egr1 gene has important role in zebrafish embryonic oculogenesis. Lens and retina with egr1 gene deletion were primitive and lacked differentiation. Such arrested retinal and lenticular development in Egr1 morphants resulted in microphthalmos.

Rabbit Early Growth Response 1 (EGR1) interaction partners

  1. Gene therapy using in vivo transfection of an Egr-1 decoy ODN significantly inhibits proliferation of VSMC and intimal hyperplasia of vein grafts in a rabbit model.

  2. Results show that EGR1 plays a key role in tendon formation, healing, and repair through BMP12 (显示 GDF7 抗体)/Smad1 (显示 SMAD1 抗体)/5/8 pathway.

  3. Collectively, these results demonstrate that Egr-1 is expressed rapidly upon HSV-1 infection and that this novel induction could be due to the NFsmall ka, CyrillicB/CREB (显示 CREB1 抗体)-mediated transactivation.

EGR1 抗原简介

Antigen Summary

The protein encoded by this gene belongs to the EGR family of C2H2-type zinc-finger proteins. It is a nuclear protein and functions as a transcriptional regulator. The products of target genes it activates are required for differentitation and mitogenesis. Studies suggest this is a cancer suppresor gene.

Alternative names and synonyms associated with EGR1

  • early growth response protein 1(Egr-1, NGFI-A) (EGR-1) 抗体
  • early growth response protein 1 (egr-1) (CNK00890) 抗体
  • early growth response 1 (EGR1) 抗体
  • early growth response 1 (Egr1) 抗体
  • early growth response 1 (egr1) 抗体
  • early growth response 1 (egr1-a) 抗体
  • early growth response protein 1 (EGR-1) 抗体
  • A530045N19Rik 抗体
  • at225 抗体
  • egr 抗体
  • egr-1 抗体
  • EGR-1-A 抗体
  • EGR1 抗体
  • ETR103 抗体
  • g0s30 抗体
  • Krox-1 抗体
  • krox-24 抗体
  • krox24 抗体
  • Ngf1 抗体
  • NGF1-A 抗体
  • Ngfi 抗体
  • ngfi-a 抗体
  • NGFIA 抗体
  • tis8 抗体
  • wu:fj64b05 抗体
  • wu:fq25f01 抗体
  • Xegr-1 抗体
  • zenk 抗体
  • Zfp-6 抗体
  • zif-268 抗体
  • Zif268 抗体
  • znf225 抗体

Protein level used designations for EGR1

early growth response protein 1(Egr-1, NGFI-A) , early growth response protein 1 (egr-1) , early growth response 1 , EGR-1 , early growth response protein 1 , nerve growth factor-induced protein A , transcription factor ETR103 , transcription factor Zif268 , zinc finger protein 225 , zinc finger protein Krox-24 , Krox-24 nuclear protein , zinc finger protein ZENK , etID309970.14 , zinc-finger transcriptional protein , early growth response protein 1-A

GENE ID SPECIES
397332 Sus scrofa
3254484 Cryptococcus neoformans var. neoformans JEC21
100618969 Monodelphis domestica
1958 Homo sapiens
481528 Canis lupus familiaris
407125 Bos taurus
13653 Mus musculus
24330 Rattus norvegicus
462097 Pan troglodytes
100716298 Cavia porcellus
100520726 Sus scrofa
373931 Gallus gallus
443547 Ovis aries
30498 Danio rerio
100008579 Taeniopygia guttata
399162 Xenopus laevis
100009491 Oryctolagus cuniculus
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