ELANE 抗体
(Elastase, Neutrophil Expressed (ELANE))
Elastases form a subfamily of serine proteases that hydrolyze many proteins in addition to elastin. Humans have six elastase genes which encode the structurally similar proteins. The product of this gene hydrolyzes proteins within specialized neutrophil lysosomes, called azurophil granules, as well as proteins of the extracellular matrix following the protein's release from activated neutrophils. The enzyme may play a role in degenerative and inflammatory diseases by its proteolysis of collagen-IV and elastin of the extracellular matrix. This protein degrades the outer membrane protein A (OmpA) of E. coli as well as the virulence factors of such bacteria as Shigella, Salmonella and Yersinia. Mutations in this gene are associated with cyclic neutropenia and severe congenital neutropenia (SCN). This gene is clustered with other serine protease gene family members, azurocidin 1 and proteinase 3 genes, at chromosome 19pter. All 3 genes are expressed coordinately and their protein products are packaged together into azurophil granules during neutrophil differentiation. [provided by RefSeq, May 2009].
recommended
recommended
ELANE 适用: 人, 猴 WB, ELISA, IHC, FACS, ICC, Neut 宿主: 小鼠 Monoclonal 6B6B10 unconjugated
recommended
ELANE 抗体 by 适用
Find ELANE 抗体 for a variety of species such as anti-Human ELANE, anti-Rat ELANE, anti-Mouse ELANE. The species listed below are among those available. Click on a link to go to the corresponding products.
ELANE 抗体 by 抗体来源
Find ELANE 抗体 with a specific 抗体来源. The 抗体来源 listed below are among those available. Click on a link to go to the corresponding products.
ELANE 抗体 by 克隆形成能力
Find available monoclonal or polyclonal ELANE 抗体. Click on a link to go to the corresponding products.
Popular ELANE 抗体
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, IF
Validations
- (7)
Cat. No.
ABIN6140110
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human, Monkey
Application
WB, ELISA, IHC, FACS, ICC, Neut
Validations
- (6)
Cat. No.
ABIN5611333
Quantity
0.1 mg
Datasheet
Datasheet
Reactivity
Human
Application
WB, IHC, IP, ICC
Validations
- (5)
Cat. No.
ABIN7431269
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human, Rat
Application
WB, ELISA, IHC, FACS, ICC, Neut
Validations
- (5)
Cat. No.
ABIN5611332
Quantity
0.1 mg
Datasheet
Datasheet
Reactivity
Human, Mouse, Rat
Application
WB, ELISA, FACS, IF (p), IHC (p)
Validations
- (3)
- (2)
Cat. No.
ABIN1386058
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
ELISA, IHC, IF
Validations
- (2)
Cat. No.
ABIN7161508
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Application
ELISA, IHC, FACS
Validations
- (2)
Cat. No.
ABIN7127640
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
ELISA, IHC
Validations
- (2)
Cat. No.
ABIN7244825
Quantity
200 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA, IF
Validations
- (2)
Cat. No.
ABIN1327510
Quantity
50 μg
Datasheet
Datasheet
Reactivity
Human
Application
ELISA, IHC, IHC (p), IEP
Validations
- (2)
Cat. No.
ABIN574169
Quantity
50 μg
Datasheet
Datasheet
Reactivity
Mouse, Rat
Application
WB, IHC (p)
Validations
- (3)
Cat. No.
ABIN4886568
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Rat
Application
WB, IHC, IP, ICC
Validations
- (1)
Cat. No.
ABIN7431275
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Mouse
Application
WB, IHC, IP, ICC
Validations
- (1)
Cat. No.
ABIN7431272
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human, Mouse
Application
WB
Validations
- (1)
Cat. No.
ABIN7256532
Quantity
200 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA
Validations
- (1)
Cat. No.
ABIN515219
Quantity
200 μL
Datasheet
Datasheet
Latest Publications for our ELANE 抗体
: "Neutrophil Extracellular Traps Associate with Clinical Stages in Breast Cancer." in: Pathology oncology research : POR, Vol. 26, Issue 3, pp. 1781-1785, (2020) (PubMed).: "The neutrophil elastase inhibitor, sivelestat, attenuates sepsis-related kidney injury in rats." in: International journal of molecular medicine, Vol. 38, Issue 3, pp. 767-75, (2016) (PubMed).
: "Prophylactic Effect of Lactobacillus pentosus strain S-PT84 on Candida Infection and Gastric Inflammation in a Murine Gastrointestinal Candidiasis Model [Errata]." in: Medical mycology journal, Vol. 57, Issue 4, pp. E81-E92, (2016) (PubMed).
: "Dogs cast NETs too: Canine neutrophil extracellular traps in health and immune-mediated hemolytic anemia." in: Veterinary immunology and immunopathology, Vol. 168, Issue 3-4, pp. 262-8, (2015) (PubMed).
: "Ozone-induced inflammation assessed in sputum and bronchial lavage fluid from asthmatics: a new noninvasive tool in epidemiologic studies on air pollution and asthma." in: Free radical biology & medicine, Vol. 27, Issue 11-12, pp. 1448-54, (2000) (PubMed).
: "Bactericidal/permeability-increasing protein release in whole blood ex vivo: strong induction by lipopolysaccharide and tumor necrosis factor-alpha." in: The Journal of infectious diseases, Vol. 175, Issue 1, pp. 108-17, (1997) (PubMed).
Aliases for ELANE 抗体
elastase, neutrophil expressed (ELANE) 抗体elastase, neutrophil expressed (Elane) 抗体
proteinase 3 (prtn3) 抗体
ELA2 抗体
Ela2 抗体
ela2 抗体
ELANE 抗体
F430011M15Rik 抗体
GE 抗体
HLE 抗体
HNE 抗体
NE 抗体
PMN-E 抗体
SCN1 抗体
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