anti-CD46 Molecule, Complement Regulatory Protein (CD46) 抗体产品概述

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anti-CD46 Molecule, Complement Regulatory Protein 抗体 (CD46)
在www.antibodies-online.cn可供368 CD46 Molecule, Complement Regulatory Protein (CD46) 抗体的23不同的供货商。 再加上,我们可以发CD46 Molecule, Complement Regulatory Protein 蛋白 (33)CD46 Molecule, Complement Regulatory Protein 试剂盒 (23)和数多这个蛋白质的别的产品。 总共430 CD46 Molecule, Complement Regulatory Protein产品已列进来了。
别名:
AFCP, AHUS2, Mcp, MIC10, TLX, TRA2.10

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  1. Cow (Bovine) Monoclonal CD46 Primary Antibody for FACS, IP - ABIN616770 : Gaggar, Shayakhmetov, Lieber: CD46 is a cellular receptor for group B adenoviruses. in Nature medicine 2003 (PubMed)
    Show all 14 references for 616770

  2. Cow (Bovine) Monoclonal CD46 Primary Antibody for FACS - ABIN616771 : Liszewski, Kemper, Price, Atkinson: Emerging roles and new functions of CD46. in Springer seminars in immunopathology 2005 (PubMed)
    Show all 14 references for 616771

  3. Cow (Bovine) Monoclonal CD46 Primary Antibody for FACS - ABIN616769 : Fleischli, Verhaagh, Havenga, Sirena, Schaffner, Cattaneo, Greber, Hemmi: The distal short consensus repeats 1 and 2 of the membrane cofactor protein CD46 and their distance from the cell membrane determine productive entry of species B adenovirus serotype 35. in Journal of virology 2005 (PubMed)
    Show all 14 references for 616769

  4. Human Monoclonal CD46 Primary Antibody for FACS, IHC (fro) - ABIN111918 : Johnstone, Russell, Loveland, McKenzie: Polymorphic expression of CD46 protein isoforms due to tissue-specific RNA splicing. in Molecular immunology 1993 (PubMed)
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  5. Human Polyclonal CD46 Primary Antibody for FACS, IHC - ABIN4900279 : Greig, Buckley, Waddington, Parker, Bhella, Pink, Rahim, Morita, Nicklin, McVey, Baker: Influence of coagulation factor x on in vitro and in vivo gene delivery by adenovirus (Ad) 5, Ad35, and chimeric Ad5/Ad35 vectors. in Molecular therapy : the journal of the American Society of Gene Therapy 2009 (PubMed)
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  6. Human Polyclonal CD46 Primary Antibody for FACS, IF - ABIN650982 : Weyand, Calton, Higashi, Kanack, So: Presenilin/gamma-secretase cleaves CD46 in response to Neisseria infection. in Journal of immunology (Baltimore, Md. : 1950) 2010 (PubMed)
    Show all 2 references for 650982

  7. Human Monoclonal CD46 Primary Antibody for FACS, IP - ABIN119580 : Sirena, Lilienfeld, Eisenhut, Kälin, Boucke, Beerli, Vogt, Ruedl, Bachmann, Greber, Hemmi: The human membrane cofactor CD46 is a receptor for species B adenovirus serotype 3. in Journal of virology 2004 (PubMed)

  8. Human Polyclonal CD46 Primary Antibody for ELISA, IHC (p) - ABIN1999639 : Miyaji, Paul, Shahrizaila, Umapathi, Yuki: Complement regulatory proteins (CD46, 55 and 59) expressed on Schwann cells: immune targets in demyelinating neuropathies? in Journal of neuroimmunology 2014 (PubMed)

更多抗CD46 Molecule, Complement Regulatory Protein的相互作用对抗体

Human CD46 Molecule, Complement Regulatory Protein (CD46) interaction partners

  1. study demonstratede that MMP-9 (显示 MMP9 抗体)-mediated shedding of CD46 is an integral part of autocrine Th1 (显示 TH1L 抗体) regulation and that this pathway is dysregulated in T cells from patients with systemic lupus erythematosus

  2. the cell surface expression level of CD46 was markedly higher in patient myeloma cells with 1q gain than in those with normal 1q copy number.

  3. Our findings reveal a novel role of CD46 in accelerating inflammatory responses upon meningococcal infection or LPS (显示 IRF6 抗体) stimulation by regulating the functional polarization and survival of macrophages.

  4. study reveals common CD46 and IFI44L (显示 IFI44L 抗体) SNPs associated with measles-specific humoral immunity, and highlights the importance of alternative splicing/virus cellular receptor isoform usage as a mechanism explaining inter-individual variation in immune response after live measles vaccine

  5. study showed no genotype differences in CD46 IVS1-1724 C>G Single nucleotide polymorphis (SNP) between Recurrent Spontaneous Abortion and fertile women

  6. Isoforms of CD46 impact on HHV-6B infection and thereby in part explain the distinct tropism of HHV-6AGS and HHV-6BPL1.

  7. Overexpression of CAPG (显示 NCAPG 抗体) is associated with glioma.

  8. This study suggests that the promoter polymorphism (rs2796267, -496 A/G) CD46 gene may be related to susceptibility of acute renal allograft rejection in Korean kidney transplantation recipients.

  9. provides insight into CD46 alternative splicing regulation with implications for its function in the immune system and for genetic disease

  10. On the basis of these results, we propose a model in which dynamic vimentin filaments target CARMIL2 to critical membrane-associated locations, where CARMIL2 regulates CP, and thus actin assembly, to create cell protrusions

Mouse (Murine) CD46 Molecule, Complement Regulatory Protein (CD46) interaction partners

  1. Changes in CD46 expression may lead to changes in VEGF and play a pathologic role in the development of age-related macular degeneration.

  2. Our findings provide evidence for expression of CD46 in the mouse eye and a role for CD46 in protection against laser-induced choroidal neovascularization

  3. This fusion is mediated by the interaction between viral glycoproteins expressed on the membrane of the infected cells and CD46 on the glial targets, and is also observed using cells expressing recombinant MV glycoproteins.

  4. CD46 isoforms function as receptors for human herpesvirus 6 and measles virus

  5. Disruption of mouse CD46 causes an accelerated spontaneous acrosome reaction in sperm and increased male fertility

  6. CD46 has a role as a receptor for fusion and entry of human herpesvirus 6 into target cells

Cow (Bovine) CD46 Molecule, Complement Regulatory Protein (CD46) interaction partners

  1. Study shows the existence of 10 distinct allelic versions of the CCP1 (显示 AGTPBP1 抗体) module of CD46; ectopic expression of the 10 bovine CD46 isoforms rendered the PK15 cells permissive to bovine viral diarrhea virus.

  2. localization of CD46 on bovine sperm membrane

Pig (Porcine) CD46 Molecule, Complement Regulatory Protein (CD46) interaction partners

  1. The results obtained in this study showed that both porcine CD46 and heparan sulfates play a major role in the initial steps of classical swine fever virus infection.

CD46 Molecule, Complement Regulatory Protein (CD46) 抗原简介

Antigen Summary

The protein encoded by this gene is a type I membrane protein and is a regulatory part of the complement system. The encoded protein has cofactor activity for inactivation of complement components C3b and C4b by serum factor I, which protects the host cell from damage by complement. In addition, the encoded protein can act as a receptor for the Edmonston strain of measles virus, human herpesvirus-6, and type IV pili of pathogenic Neisseria. Finally, the protein encoded by this gene may be involved in the fusion of the spermatozoa with the oocyte during fertilization. Mutations at this locus have been associated with susceptibility to hemolytic uremic syndrome. Alternatively spliced transcript variants encoding different isoforms have been described.

Alternative names and synonyms associated with CD46 Molecule, Complement Regulatory Protein (CD46)

  • capping protein (actin filament), gelsolin-like (CAPG) 抗体
  • CD46 antigen, complement regulatory protein (Cd46) 抗体
  • CD46 molecule, complement regulatory protein (CD46) 抗体
  • CD46 molecule, complement regulatory protein (Cd46) 抗体
  • Membrane cofactor protein-like (LOC100341359) 抗体
  • AFCP 抗体
  • AHUS2 抗体
  • Mcp 抗体
  • MIC10 抗体
  • TLX 抗体
  • TRA2.10 抗体

Protein level used designations for CD46

actin regulatory protein CAP-G , actin-regulatory protein CAP-G , gelsolin-like capping protein , macrophage capping protein , macrophage-capping protein , membrane cofactor protein , membrane cofactor protein(GMP1-full) , CD46 antigen, complement regulatory protein , antigen identified by monoclonal antibody TRA-2-10 , complement membrane cofactor protein , measles virus receptor , membrane cofactor protein (CD46, trophoblast-lymphocyte cross-reactive antigen) , trophoblast leucocyte common antigen , trophoblast leukocyte common antigen , trophoblast-lymphocyte cross-reactive antigen , brain microvascular membrane cofactor

GENE ID SPECIES
822 Homo sapiens
17221 Mus musculus
100135498 Cavia porcellus
4179 Homo sapiens
616002 Bos taurus
280851 Bos taurus
396922 Sus scrofa
29333 Rattus norvegicus
100341359 Oryctolagus cuniculus
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