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beta-2 Microglobulin Protein (AA 21-119) (His tag)

B2M 宿主: 人 宿主: 大肠杆菌(E. Coli) Recombinant > 95 % by SDS - PAGE SDS
产品编号 ABIN667146
发货至: 中国
  • 抗原 See all beta-2 Microglobulin (B2M) 蛋白
    beta-2 Microglobulin (B2M) (beta-2-Microglobulin (B2M))
    蛋白类型
    Recombinant
    产品特性
    AA 21-119
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    资源
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    大肠杆菌(E. Coli)
    标记
    This beta-2 Microglobulin protein is labelled with His tag.
    应用范围
    SDS-PAGE (SDS)
    产品特性
    B2M, 21-119aa, Human, His tag, E.coli
    纯度
    > 95 % by SDS - PAGE
    Top Product
    Discover our top product B2M 蛋白
  • 限制
    仅限研究用
  • 状态
    Liquid
    浓度
    0.5 mg/ml (determined by Bradford assay)
    缓冲液
    Liquid. In 20mM Tris-HCl buffer (pH8.0) containing 20% glycerol, 2mM DTT, 100mM NaCl
    储存条件
    4 °C
  • 抗原
    beta-2 Microglobulin (B2M) (beta-2-Microglobulin (B2M))
    别名
    B2M (B2M 产品)
    别名
    Ly-m11 Protein, beta2-m Protein, beta2m Protein, bwm Protein, wu:fa94c05 Protein, wu:fb10a09 Protein, b2m-W01 Protein, b2m-W03 Protein, b2m-Z01 Protein, b2m-Z02 Protein, b2m-Z03 Protein, B2M Protein, b2m Protein, B2MG Protein, wu:fb66f11 Protein, wu:fj01f08 Protein, zgc:64161 Protein, b-2-m Protein, beta-2-microglobulin Protein, beta-2 microglobulin Protein, beta-2-microglobulin S homeolog Protein, beta-2-microglobulin, like Protein, B2M Protein, B2m Protein, b2m Protein, b2m.S Protein, b2ml Protein
    背景
    Beta2 microglobulin, also known as B2M, is a component of MHC class I molecules, Involved in the presentation of peptide antigens to the immune system. B2M is a protein found on the surface of many cells and plentiful on the surface of white blood cells. Increased production or destruction of these cells causes B2M levels in the blood to increase. This increase is seen in people with cancers involving white blood cells, but it is particularly meaningful in people newly diagnosed with multiple myeloma. Multiple myeloma is a malignancy (cancer) of a certain kind of white blood cell, called a plasma cell. B2M Testing is done primarily when evaluating a person for certain kinds of cancer affecting white blood cells including chronic lymphocytic leukemia, non-Hodgkin's lymphoma, and multiple myeloma or kidney disease. Recombinant B2M protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques. Synonyms: Beta-2-microglobulin, CDABP0092, HDCMA22P. NCBI no.: NP_004039
    分子量
    14.0kDa (120aa), confirmed by MALDI-TOF
    途径
    TCR Signaling, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process
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