Tumor Necrosis Factor (TNF) (Active) 蛋白

ABIN413823 产品详细信息, 供应商: Log in to see
蛋白名称
  • TNF
  • tnf
  • dif
  • tnfa
  • xtnf
  • TNF-a
  • tnfsf2
  • tnf-alpha
  • TNF-alpha
  • DIF
  • TNFA
  • TNFSF2
  • TNFalpha
  • Tnfa
  • Tnfsf1a
  • RATTNF
  • TNFa
  • cTNF
  • TNF-ALPHA
  • Cachectin
  • Tnf-alpha
  • tnfa-like
  • tumor necrosis factor (TNF superfamily, member 2)
  • tumor necrosis factor
  • tumour necrosis factor alpha-like
  • tumor necrosis factor alpha
  • lipopolysaccharide-induced TNF factor
  • tumor necrosis factor b (TNF superfamily, member 2)
  • TNF
  • tnf
  • tnf-alpha
  • LITAF
  • Tnf
  • tnfb
宿主
小鼠
115
49
29
9
6
5
5
3
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
资源
大肠杆菌(E. Coli)
155
26
16
6
4
3
3
2
2
2
2
1
1
蛋白类型
Recombinant
生物活性
Active
应用范围
High Pressure Liquid Chromatography (HPLC), SDS-PAGE (SDS)
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纯度 ≥98 % by SDS-PAGE
≥98 % by HPLC
内毒素水平 <0.1 ng/μg
ProductDetails: Biological Activity Comment The ED₅₀ as determined by the cytolysis of murine L929 cells in the presence of actinomycin D is < 0.1 ng/ml, corresponding to a specific activity of > 1 x 10⁷ units/mg.
背景 Tumor Necrosis Factor-α TNF-α) is a potent lymphoid factor that exerts cytotoxic effects on a wide range of tumor cells and certain other target cells. Murine TNF-α is a 17.5 kDa protein containing 156 amino acid residues.

Alternative Names: Tumor necrosis factor, Cachectin, TNF-alpha, Tumor necrosis factor ligand superfamily member 2
分子量 17.5 kDa
基因ID 21926
UniProt P06804
研究领域 Inflammation, Cancer, Virology
途径 NF-kappaB Signaling, Apoptosis, Caspase Cascade in Apoptosis, Cellular Response to Molecule of Bacterial Origin, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Positive Regulation of Endopeptidase Activity, Hepatitis C, Protein targeting to Nucleus
应用备注 Optimal working dilution should be determined by the investigator.
限制 仅限研究用
状态 Lyophilized
溶解方式 Reconstitute in H₂O to a concentration of 0.1-1.0 mg/mL. This solution can then be diluted into other aqueous buffers and stored at 4 °C for 1 week or -20 °C for future use.
缓冲液 Steriled and lyophilized from 5 mM Tris, pH 8.0.
注意事项 Centrifuge the vial prior to opening.
储存条件 -20 °C
有效期 12 months
厂商提供的图像
Western Blotting (WB) image for Tumor Necrosis Factor (TNF) (Active) protein (ABIN413823) Tumor Necrosis Factor (TNF) (Active) protein
有引用在: Srivastava, Qin, Wedhas, Arnush, Linkhart, Chadwick, Kumar: "Tumor necrosis factor-alpha augments matrix metalloproteinase-9 production in skeletal muscle cells through the activation of transforming growth factor-beta-activated kinase 1 (TAK1)-dependent signaling pathway." in: The Journal of biological chemistry, Vol. 282, Issue 48, pp. 35113-24, 2007 (PubMed).

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