ABCB1 Protein (His tag)
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- 抗原 See all ABCB1 蛋白
- ABCB1 (ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 1 (ABCB1))
- 蛋白类型
- Recombinant
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宿主
- 人
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资源
- Insect cells (Sf9)
- 标记
- This ABCB1 protein is labelled with His tag.
- 应用范围
- Antibody Production (AbP), Standard (STD)
- 产品特性
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- Recombinant human CD243 / MDR1 (C-term DDK tag) protein expressed in sf9 cells.
- Produced with end-sequenced ORF clone
- 纯度
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
- Top Product
- Discover our top product ABCB1 蛋白
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ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 1 (ABCB1) (AA 620-709) protein (GST tag)
ABCB1 宿主: 人 宿主: 小麦胚 Recombinant ELISA, WB, AP, AA
ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 1 (ABCB1) (AA 491-694) protein (His-IF2DI Tag)ABCB1 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant Greater than 90 % by SDS-PAGE gel analyses ELISA, WB
ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 1 (ABCB1) (AA 1-1280) protein (Strep Tag)Crystallography grade ABCB1 宿主: 人 宿主: Tobacco (Nicotiana tabacum) Recombinant >80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. ELISA, WB, SDS
ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 1 (ABCB1) (AA 353-711) protein (His tag)Crystallography grade ABCB1 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. ELISA, WB, SDS, Crys
ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 1 (ABCB1) (AA 996-1280) protein (His tag)Crystallography grade ABCB1 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. ELISA, WB, SDS, Crys
ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 1 (ABCB1) protein (DYKDDDDK Tag)ABCB1 宿主: 人 宿主: Insect cells (Sf9) Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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- 应用备注
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - 说明
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The tag is located at the C-terminal.
- 限制
- 仅限研究用
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- 浓度
- 50 μg/mL
- 缓冲液
- 50 mM Tris-HCl, pH 8.0, 100 mM glycine, 10 % glycerol. Store at -80C. Avoid repeated freeze-thaw cycles. Stable for at least 3 months from receipt of products under proper storage and handling conditions.
- 储存条件
- -80 °C
- 储存方法
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- 抗原
- ABCB1 (ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 1 (ABCB1))
- 别名
- Cd243,mdr1 (ABCB1 产品)
- 别名
- ABC20 Protein, CD243 Protein, CLCS Protein, GP170 Protein, MDR1 Protein, P-GP Protein, PGY1 Protein, Abcb1 Protein, Mdr1a Protein, p-gp Protein, xemdr Protein, Mdr1 Protein, Mdr1b Protein, Pgy-1 Protein, Pgy1 Protein, mdr Protein, ABCB1 Protein, PGP1 Protein, ATP binding cassette subfamily B member 1 Protein, ATP binding cassette subfamily B member 1A Protein, ATP binding cassette subfamily B member 1 L homeolog Protein, ATP-binding cassette, sub-family B (MDR/TAP), member 1B Protein, ABCB1 Protein, Abcb1a Protein, abcb1.L Protein, Abcb1b Protein, Abcb1 Protein
- 背景
- The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance. The protein encoded by this gene is an ATP-dependent drug efflux pump for xenobiotic compounds with broad substrate specificity. It is responsible for decreased drug accumulation in multidrug-resistant cells and often mediates the development of resistance to anticancer drugs. This protein also functions as a transporter in the blood-brain barrier.
- 分子量
- 41 kDa
- NCBI登录号
- NP_000918
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