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VEGF 165 (Active) 蛋白

宿主: 人 宿主: 大肠杆菌(E. Coli) Recombinant < 98 % by SDS-PAGE gel and HPLC analyses. Active
产品编号 ABIN2469208
发货至: 中国
  • 抗原
    VEGF 165
    蛋白类型
    Recombinant
    生物活性
    Active
    宿主
    • 17
    • 3
    • 2
    资源
    • 10
    • 7
    • 1
    • 1
    • 1
    • 1
    • 1
    大肠杆菌(E. Coli)
    序列
    APMAEGGGQN HHEVVKFMDV YQRSYCHPIE TLVDIFQEYP DEIEYIFKPS CVPLMRCGGC CNDEGLECVP TEESNITMQI MRIKPHQGQH IGEMSFLQHN KCECRPKKDR ARQENPCGPC SERRKHLFVQ DPQTCKCSCK NTDSRCKARQ LELNERTCRC DKPRR
    产品特性
    Biological activity was determined by the dose - dependent stimulation of the proliferation of human umbilical vein endothelial cells (HUVEC) using a concentration range of 1.0 - 8.0 ng/mL.
    纯度
    < 98 % by SDS-PAGE gel and HPLC analyses.
    内毒素水平
    Endotoxin level is less than 0.1 ng per μg (1 EU/μg).
  • 限制
    仅限研究用
  • 状态
    Lyophilized
    注意事项
    As with any protein, exposing VEGF165 recombinant protein to repeated freeze / thaw cycles is not recommended. When working with proteins care should be taken to keep recombinant protein at a cool and stable temperature.
    储存条件
    -20 °C
    储存方法
    The recombinant protein is stable for at least 2 years from date of receipt at -20 °C. Reconstituted VEGF165 is stable for at least 3 months when stored in working aliquots with a carrier protein at -20 °C.
    有效期
    24 months
  • 抗原
    VEGF 165
    别名
    VEGF165
    背景
    VEGF is a potent growth and angiogenic cytokine. It stimulates proliferation and survival of endothelial cells, and promotes angiogenesis and vascular permeability. Expressed in vascularized tissues, VEGF plays a prominent role in normal and pathological angiogenesis. Substantial evidence implicates VEGF in the induction of tumor metastasis and intra-ocular neovascular syndromes. VEGF signals through the three receptors , fms-like tyrosine kinase (flt-1), KDR gene product (the murine homolog of KDR is the flk-1 gene product) and the flt4 gene product. Recombinant human VEGF165 is a 38.2 kDa disulfide-linked homodimeric protein consisting of two 165 amino acid polypeptide chains.
    基因ID
    7422
    NCBI登录号
    NP_001028928
    OMIM
    76781487
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