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VEGF 165 (Active) 蛋白

ABIN2469208 产品详细信息, 供应商: Log in to see
蛋白名称
宿主

32
4
4
资源
大肠杆菌(E. Coli)
27
5
3
2
2
1
蛋白类型
Recombinant
生物活性
Active
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Supplier Product No.
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序列 APMAEGGGQN HHEVVKFMDV YQRSYCHPIE TLVDIFQEYP DEIEYIFKPS CVPLMRCGGC CNDEGLECVP TEESNITMQI MRIKPHQGQH IGEMSFLQHN KCECRPKKDR ARQENPCGPC SERRKHLFVQ DPQTCKCSCK NTDSRCKARQ LELNERTCRC DKPRR
产品特性 Biological activity was determined by the dose - dependent stimulation of the proliferation of human umbilical vein endothelial cells (HUVEC) using a concentration range of 1.0 - 8.0 ng/mL.
纯度 < 98 % by SDS-PAGE gel and HPLC analyses.
内毒素水平 Endotoxin level is less than 0.1 ng per μg (1 EU/μg).
背景 VEGF is a potent growth and angiogenic cytokine. It stimulates proliferation and survival of endothelial cells, and promotes angiogenesis and vascular permeability. Expressed in vascularized tissues, VEGF plays a prominent role in normal and pathological angiogenesis. Substantial evidence implicates VEGF in the induction of tumor metastasis and intra-ocular neovascular syndromes. VEGF signals through the three receptors , fms-like tyrosine kinase (flt-1), KDR gene product (the murine homolog of KDR is the flk-1 gene product) and the flt4 gene product. Recombinant human VEGF165 is a 38.2 kDa disulfide-linked homodimeric protein consisting of two 165 amino acid polypeptide chains.
基因ID 7422
NCBI登录号 NP_001028928
OMIM 76781487
研究领域 Cytokines, Growth Factors, Receptors, Immunology, Inflammation, Signaling
限制 仅限研究用
状态 Lyophilized
注意事项 As with any protein, exposing VEGF165 recombinant protein to repeated freeze / thaw cycles is not recommended. When working with proteins care should be taken to keep recombinant protein at a cool and stable temperature.
储存条件 -20 °C
储存方法 The recombinant protein is stable for at least 2 years from date of receipt at -20 °C. Reconstituted VEGF165 is stable for at least 3 months when stored in working aliquots with a carrier protein at -20 °C.
有效期 24 months
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