GDF3 蛋白
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- 抗原 See all GDF3 蛋白
- GDF3 (Growth Differentiation Factor 3 (GDF3))
- 蛋白类型
- Recombinant
- 生物活性
- Active
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宿主
- 人
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资源
- 大肠杆菌（E. Coli）
- 序列
- AAIPVPKLSC KNLCHRHQLF INFRDLGWHK WIIAPKGFMA NYCHGECPFS LTISLNSSNY AFMQALMHAV DPEIPQAVCI PTKLSPISML YQDNNDNVIL RHYEDMVVDE CGCG
- 产品特性
- Biological activity was determined by its ability to inhibit induced alkaline phosphatase production by ATDC - 5 chondrogenic cells. The ED50 for this effect is 100 - 150 ng/mL.
- 纯度
- < 98 % by SDS-PAGE gel and HPLC analyses.
- 内毒素水平
- Endotoxin level is less than 0.1 ng per μg (1 EU/μg).
- Top Product
- Discover our top product GDF3 蛋白
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Growth Differentiation Factor 3 (GDF3) (AA 251-364) protein (His-IF2DI Tag)
GDF3 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant Greater than 95 % by SDS-PAGE gel analyses WB, ELISA
Growth Differentiation Factor 3 (GDF3) (AA 265-364) protein (GST tag)GDF3 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AA, AP
Growth Differentiation Factor 3 (GDF3) (AA 1-364) protein (GST tag)GDF3 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AA, AP
Growth Differentiation Factor 3 (GDF3) (AA 251-364) protein (His tag)Crystallography grade GDF3 宿主: 人 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys
Growth Differentiation Factor 3 (GDF3) (AA 253-366) protein (His tag)Crystallography grade GDF3 宿主: 小鼠 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys
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- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 注意事项
- As with any protein, exposing GDF-3 recombinant protein to repeated freeze / thaw cycles is not recommended. When working with proteins care should be taken to keep recombinant protein at a cool and stable temperature.
- 储存条件
- -20 °C
- 储存方法
- The recombinant protein is stable for at least 2 years from date of receipt at -20 °C. Reconstituted GDF-3 is stable for at least 3 months when stored in working aliquots with a carrier protein at -20 °C.
- 有效期
- 24 months
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- 抗原
- GDF3 (Growth Differentiation Factor 3 (GDF3))
- 别名
- GDF-3 (GDF3 产品)
- 别名
- KFS3 Protein, MCOP7 Protein, MCOPCB6 Protein, C78318 Protein, Gdf-3 Protein, Vgr-2 Protein, Vgr2 Protein, ecat9 Protein, RGD1564178 Protein, CVG1 Protein, der Protein, derriere Protein, gdf3-a Protein, vgr-2 Protein, vgr2 Protein, growth differentiation factor 3 Protein, growth differentiation factor 3 S homeolog Protein, GDF3 Protein, Gdf3 Protein, gdf3.S Protein
- 背景
- GDF-3 is a member of the TGF-beta superfamily of growth and differentiation factors, and is highly homologous to GDF-9. Unlike most TGF-beta family members, GDF-3 and GDF-9 are not disulfide-linked dimers. GDF-3 is expressed in adult bone marrow, spleen, thymus, and adipose tissue. The expression of GDF-3 is upregulated in high-fat-fed wild-type FABP4/aP2 null mice and was associated with obesity, but not with the related hyperglycemia/hyperinsulinemia which characterizes Type 2 diabetes. Recombinant human GDF-3 is a 26.0 kDa non-disulfide-linked homodimer containing two 114 amino acid polypeptide chains.
- 基因ID
- 9573
- NCBI登录号
- NP_065685
- OMIM
- 10190670
- UniProt
- Q9NR23
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