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Growth Differentiation Factor 3 (GDF3) (Active) 蛋白

ABIN2468472 产品详细信息, 供应商: Log in to see
蛋白名称
  • KFS3
  • MCOP7
  • MCOPCB6
  • C78318
  • Gdf-3
  • Vgr-2
  • Vgr2
  • ecat9
  • RGD1564178
  • CVG1
  • der
  • derriere
  • gdf3-a
  • vgr-2
  • vgr2
  • growth differentiation factor 3
  • growth/differentiation factor 3-like
  • GDF3
  • Gdf3
  • LOC100346534
  • gdf3
  • LOC100510963
宿主

17
2
1
1
资源
大肠杆菌(E. Coli)
13
2
2
1
蛋白类型
Recombinant
生物活性
Active
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Supplier Product No.
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序列 AAIPVPKLSC KNLCHRHQLF INFRDLGWHK WIIAPKGFMA NYCHGECPFS LTISLNSSNY AFMQALMHAV DPEIPQAVCI PTKLSPISML YQDNNDNVIL RHYEDMVVDE CGCG
产品特性 Biological activity was determined by its ability to inhibit induced alkaline phosphatase production by ATDC - 5 chondrogenic cells. The ED50 for this effect is 100 - 150 ng/mL.
纯度 < 98 % by SDS-PAGE gel and HPLC analyses.
内毒素水平 Endotoxin level is less than 0.1 ng per μg (1 EU/μg).
背景 GDF-3 is a member of the TGF-beta superfamily of growth and differentiation factors, and is highly homologous to GDF-9. Unlike most TGF-beta family members, GDF-3 and GDF-9 are not disulfide-linked dimers. GDF-3 is expressed in adult bone marrow, spleen, thymus, and adipose tissue. The expression of GDF-3 is upregulated in high-fat-fed wild-type FABP4/aP2 null mice and was associated with obesity, but not with the related hyperglycemia/hyperinsulinemia which characterizes Type 2 diabetes. Recombinant human GDF-3 is a 26.0 kDa non-disulfide-linked homodimer containing two 114 amino acid polypeptide chains.
基因ID 9573
NCBI登录号 NP_065685
OMIM 10190670
UniProt Q9NR23
限制 仅限研究用
状态 Lyophilized
注意事项 As with any protein, exposing GDF-3 recombinant protein to repeated freeze / thaw cycles is not recommended. When working with proteins care should be taken to keep recombinant protein at a cool and stable temperature.
储存条件 -20 °C
储存方法 The recombinant protein is stable for at least 2 years from date of receipt at -20 °C. Reconstituted GDF-3 is stable for at least 3 months when stored in working aliquots with a carrier protein at -20 °C.
有效期 24 months
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