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FGF7 蛋白

FGF7 宿主: 人 宿主: 大肠杆菌(E. Coli) Recombinant > 95 % as determined by SDS-PAGE (CBB staining) WB Active
产品编号 ABIN2452198
发货至: 中国
  • 抗原 See all FGF7 蛋白
    FGF7 (Fibroblast Growth Factor 7 (FGF7))
    蛋白类型
    Recombinant
    生物活性
    Active
    宿主
    • 20
    • 8
    • 4
    • 3
    • 1
    • 1
    • 1
    资源
    • 19
    • 5
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    大肠杆菌(E. Coli)
    应用范围
    Western Blotting (WB)
    产品特性
    The human FGF-7 lacking the signal sequence (1-31 aa) was expressed in E. coli and purified by the chromatographic procedures. This product is an intact enzyme without tag with 19 kDa size.
    纯度
    > 95 % as determined by SDS-PAGE (CBB staining)
    过滤
    Sterile filtered
    Top Product
    Discover our top product FGF7 蛋白
  • 应用备注
    1. Mitogen for epithelial cells
    2. Western blot control for anti-FGF-7 antibodies
    3. Acceleration of wound healing is implied.
    4. Acceleration of hair development is implied.
    说明

    Activity: The ED50 as determined by a cell proliferation assay using MTS assay kit (CellTiter 96,Promega) with human keratinocyte JCRB141 cells was < 10 ng/mL.

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1.0 mg/mL
    缓冲液
    PBS (10 mM Na-phosphate, 150 mM NaCl) pH 7.2, 50 % glycerol
    注意事项
    Avoid repeated freeze-thaw.
    Quick freezing with liquid nitrogen and rapid thawing on water is desirable when necessary.
    储存条件
    -20 °C/-80 °C
    储存方法
    Store at -20 C (For long term storage: -80 C).
  • Aaronson, Bottaro, Miki, Ron, Finch, Fleming, Ahn, Taylor, Rubin: "Keratinocyte growth factor. A fibroblast growth factor family member with unusual target cell specificity." in: Annals of the New York Academy of Sciences, Vol. 638, pp. 62-77, (1992) (PubMed).

    Rubin, Osada, Finch, Taylor, Rudikoff, Aaronson: "Purification and characterization of a newly identified growth factor specific for epithelial cells." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 86, Issue 3, pp. 802-6, (1989) (PubMed).

  • 抗原
    FGF7 (Fibroblast Growth Factor 7 (FGF7))
    别名
    Keratinocyte Growth Factor (KGF/FGF7) (FGF7 产品)
    别名
    HBGF-7 Protein, KGF Protein, Kgf Protein, kgf Protein, FGF-7 Protein, fgf7 Protein, fibroblast growth factor 7 Protein, fibroblast growth factor 7 L homeolog Protein, FGF7 Protein, Fgf7 Protein, fgf7 Protein, fgf7.L Protein
    背景
    Keratinocyte Growth Factor (KGF), also known as Fibroblast Growth Factor 7 (FGF-7), is a member of fibroblast growth factor (FGF) family. Although FGF-7 has heparin binding activity similar to FGF-1, its mitogenic activity is predominantly exhibited in keratinocytes. It is not effective to fibroblasts and endothelial cells.
    基因ID
    2252
    UniProt
    P21781
    途径
    RTK signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway
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