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LUM Protein (AA 19-338) (His tag)

LUM 宿主: 人 宿主: HEK-293 Cells Recombinant >95 % as determined by reduced SDS-PAGE.
产品编号 ABIN2181489
发货至: 中国
  • 抗原 See all LUM 蛋白
    LUM (Lumican (LUM))
    蛋白类型
    Recombinant
    产品特性
    AA 19-338
    宿主
    • 8
    • 4
    • 1
    • 1
    • 1
    • 1
    资源
    • 4
    • 4
    • 3
    • 2
    • 2
    • 1
    HEK-293 Cells
    标记
    This LUM protein is labelled with His tag.
    序列
    AA 19-338
    产品特性
    This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 37.5 kDa. The protein migrates as 50-65 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
    纯度
    >95 % as determined by reduced SDS-PAGE.
    过滤
    0.22 μm filtered
    内毒素水平
    Less than 1.0 EU per μg by the LAL method.
    Top Product
    Discover our top product LUM 蛋白
  • 限制
    仅限研究用
  • 状态
    Lyophilized
    缓冲液
    PBS, pH 7.4
    注意事项
    Please avoid repeated freeze-thaw cycles.
    储存条件
    -20 °C
    储存方法
    No activity loss was observed after storage at: In lyophilized state for 1 year (4 °C), After reconstitution under sterile conditions for 3 months (-70 °C).
  • 抗原
    LUM (Lumican (LUM))
    别名
    Lumican (LUM 产品)
    别名
    MGC64527 Protein, zgc:86661 Protein, ldc Protein, slrr2d Protein, DKFZp468L1116 Protein, LDC Protein, SLRR2D Protein, Ldc Protein, lumican Protein, lumican L homeolog Protein, LUM Protein, lum.L Protein, lum Protein, CpipJ_CPIJ010209 Protein, Lum Protein
    背景
    Lumican (LUM) is also known as Keratan sulfate proteoglycan lumican, KSPG lumican,LDC and SLRR2D, which belongs to the small leucine-rich proteoglycan (SLRP) family and SLRP class II subfamily. LUM /Lumican is present in the extracellular matrix of human articular cartilage at all ages, although its abundance is far greater in the adult. In the adult cartilage LUM /Lumican exists predominantly in a glycoprotein form lacking keratan sulfate, whereas the juvenile form of the molecule is a proteoglycan. LUM participates in the maintenance of tissue homeostasis and modulates cellular functions including cell proliferation, migration, and differentiation. The expression of LUM has been correlated to the growth and metastasis of various malignancies.
    分子量
    37.5 kDa
    NCBI登录号
    NP_002336
    途径
    Glycosaminoglycan Metabolic Process
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