CD130/gp130 Protein (AA 23-617) (Fc Tag)
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- 抗原 See all CD130/gp130 (IL6ST) 蛋白
- CD130/gp130 (IL6ST) (Interleukin 6 Signal Transducer (Gp130, Oncostatin M Receptor) (IL6ST))
- 蛋白类型
- Recombinant
- 产品特性
- AA 23-617
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宿主
- 小鼠
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资源
- HEK-293 Cells
- 标记
- This CD130/gp130 protein is labelled with Fc Tag.
- 序列
- AA 23-617
- 产品特性
- This protein carries a human IgG1 Fc tag at the C-terminus. The protein has a calculated MW of 93.3 kDa. The protein migrates as 120-130 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
- 纯度
- >90 % as determined by SDS-PAGE.
- 过滤
- 0.22 μm filtered
- 内毒素水平
- Less than 1.0 EU per μg by the LAL method.
- Top Product
- Discover our top product IL6ST 蛋白
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Interleukin 6 Signal Transducer (Gp130, Oncostatin M Receptor) (IL6ST) (AA 23-122) protein (GST tag)
IL6ST 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA
Interleukin 6 Signal Transducer (Gp130, Oncostatin M Receptor) (IL6ST) (Active) protein (His tag)IL6ST 宿主: 小鼠 宿主: HEK-293 Cells Recombinant > 97 % as determined by SDS-PAGE Active
Interleukin 6 Signal Transducer (Gp130, Oncostatin M Receptor) (IL6ST) (Active) protein (His tag,Fc Tag)IL6ST 宿主: 大鼠 宿主: HEK-293 Cells Recombinant > 95 % as determined by SDS-PAGE Active
Interleukin 6 Signal Transducer (Gp130, Oncostatin M Receptor) (IL6ST) (Active) protein (His tag)IL6ST 宿主: 大鼠 宿主: HEK-293 Cells Recombinant > 97 % as determined by SDS-PAGE Active
Interleukin 6 Signal Transducer (Gp130, Oncostatin M Receptor) (IL6ST) (AA 642-918) protein (His tag)Crystallography grade IL6ST 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
Interleukin 6 Signal Transducer (Gp130, Oncostatin M Receptor) (IL6ST) (AA 640-917) protein (His tag)Crystallography grade IL6ST 宿主: 小鼠 宿主: 大肠杆菌（E. Coli） Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
Interleukin 6 Signal Transducer (Gp130, Oncostatin M Receptor) (IL6ST) (AA 23-619) protein (His tag)Crystallography grade IL6ST 宿主: 人 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
Interleukin 6 Signal Transducer (Gp130, Oncostatin M Receptor) (IL6ST) (AA 23-918) protein (rho-1D4 tag)Crystallography grade IL6ST 宿主: 人 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
Interleukin 6 Signal Transducer (Gp130, Oncostatin M Receptor) (IL6ST) (AA 23-917) protein (rho-1D4 tag)Crystallography grade IL6ST 宿主: 小鼠 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
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- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 缓冲液
- Tris with Glycine, Arginine and NaCl, pH 7.5
- 注意事项
- Please avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- No activity loss was observed after storage at: In lyophilized state for 1 year (4 °C), After reconstitution under sterile conditions for 3 months (-70 °C).
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- 抗原
- CD130/gp130 (IL6ST) (Interleukin 6 Signal Transducer (Gp130, Oncostatin M Receptor) (IL6ST))
- 别名
- Gp130 (IL6ST 产品)
- 别名
- CD130 Protein, CDW130 Protein, GP130 Protein, IL-6RB Protein, 5133400A03Rik Protein, AA389424 Protein, BB405851 Protein, D13Ertd699e Protein, gp130 Protein, Ac1055 Protein, Gp130 Protein, Il-6rb Protein, IL-6 Protein, interleukin 6 signal transducer Protein, IL6ST Protein, Il6st Protein, il6st Protein
- 背景
- Interleukin-6 receptor subunit beta (IL6ST) is also known as IL-6 receptor subunit beta, IL-6R subunit beta, IL-6R-beta, IL-6RB, Interleukin-6 signal transducer, Membrane glycoprotein 130 (gp130), CD130, Oncostatin-M receptor subunit alpha and Il6st,which is single-pass type I membrane protein. IL6ST /gp130 /CD130 can be found in tissues such as brain, heart, thymus, spleen, kidney, lung and liver and found in all the cell lines tested except BaF-B03.The expression of IL-6ST /gp130 is not restricted to IL6-responsive cells. The receptor systems for IL6, LIF, OSM, CNTF, IL11, CTF1 and BSF3 can utilize gp130 for initiating signal transmission. IL6ST /CD130 can bind to IL6 /IL6R (alpha chain) complex, resulting in the formation of high-affinity IL6 binding sites, and transduce the signal. IL6ST /GP130 does not bind IL6 and may have a role in embryonic development.
- 分子量
- 93.3 kDa
- NCBI登录号
- NP_034690
- 途径
- JAK/STAT Signaling, Cellular Glucan Metabolic Process, Autophagy, Smooth Muscle Cell Migration, Cancer Immune Checkpoints
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