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CD27 Protein (AA 21-192) (Fc Tag)

CD27 宿主: 人 宿主: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE. Active
产品编号 ABIN2180735
发货至: 中国
  • 抗原 See all CD27 蛋白
    CD27 (CD27 Molecule (CD27))
    蛋白类型
    Recombinant
    生物活性
    Active
    产品特性
    AA 21-192
    宿主
    • 23
    • 11
    • 3
    • 3
    • 1
    资源
    • 18
    • 6
    • 5
    • 4
    • 2
    • 2
    • 1
    • 1
    HEK-293 Cells
    标记
    This CD27 protein is labelled with Fc Tag.
    序列
    AA 21-192
    产品特性
    This protein carries a human IgG1 Fc tag at the C-terminus. The protein has a calculated MW of 45.9 kDa. The protein migrates as 45-65 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
    纯度
    >95 % as determined by SDS-PAGE.
    过滤
    0.22 μm filtered
    内毒素水平
    Less than 1.0 EU per μg by the LAL method.
    Top Product
    Discover our top product CD27 蛋白
  • 限制
    仅限研究用
  • 状态
    Lyophilized
    缓冲液
    50 mM Tris, 100 mM Glycine, pH 7.5
    注意事项
    Please avoid repeated freeze-thaw cycles.
    储存条件
    -20 °C
    储存方法
    No activity loss was observed after storage at: In lyophilized state for 1 year (4 °C), After reconstitution under sterile conditions for 3 months (-70 °C).
  • 抗原
    CD27 (CD27 Molecule (CD27))
    别名
    CD27 (CD27 产品)
    别名
    TNFRSF7 Protein, S152 Protein, Tnfrsf7 Protein, Tp55 Protein, S152. LPFS2 Protein, T14 Protein, CD27 molecule Protein, CD27 antigen Protein, CD27 Protein, Cd27 Protein
    背景
    CD Antigen CD27 is also known as Tumor necrosis factor receptor superfamily member 7 (TNFRSF7), which belongs to TNF-receptor superfamily. CD27 / TNFRSF7 is found in most T-lymphocytes. CD27 / TNFRSF7 is required for generation and long-term maintenance of T cell immunity. It binds to ligand CD70, and plays a key role in regulating B-cell activation and immunoglobulin synthesis. This receptor transduces signals that lead to the activation of NF-κB and MAPK8/JNK. CD27 has been shown to interact with SIVA1, TRAF2 and TRAF3.
    分子量
    45.9 kDa
    NCBI登录号
    NP_001233
    途径
    Production of Molecular Mediator of Immune Response, Cancer Immune Checkpoints
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