FGF2 蛋白
-
- 抗原 See all FGF2 蛋白
- FGF2 (Fibroblast Growth Factor 2 (Basic) (FGF2))
- 蛋白类型
- Recombinant
- 生物活性
- Active
-
宿主
- 人
-
资源
- 大肠杆菌(E. Coli)
- 序列
- AAGSITTLPA LPEDGGSGAF PPGHFKDPKR LYCKNGGFFL RIHPDGRVDG VREKSDPHIK LQLQAEERGV VSIKGVCANR YLAMKEDGRL LASKCVTDEC FFFERLESNN YNTYRSRKYT SWYVALKRTG QYKLGSKTGP GQKAILFLPM SAKS
- 产品特性
-
Purified recombinant Human FGF basic protein
Expression System: E.coli
Bioactivity: Assay #1: The ED50 as determined by the dose-dependent stimulation of thymidine uptake by BaF3 cells expressing FGF receptors is ? 0.5 ng/mL, corresponding to a specific activity of ? 2 x 10^6 units/mg. Assay #2: The ED50 was determined by a cell proliferation assay using balb/c 3T3 cells is ? 0.1 ng/mL, corresponding to a specific activity of ? 1 x 10^7 units/mg. - 纯度
- > 95 % pure
- 内毒素水平
- < 0.1 ng per μg (1 EU/μg).
- Top Product
- Discover our top product FGF2 蛋白
-
-
- 应用备注
- Each Investigator should determine their own optimal working dilution for specific applications.
- 说明
-
Biological activity: Assay #1: The ED50 as determined by the dose-dependent stimulation of thymidine uptake by BaF3 cells expressing FGF receptors is approx. 0.5 ng/mL, corresponding to a specific activity of approx. 2 x 10^6 units/mg. Assay #2: The ED50 was determined by a cell proliferation assay using balb/c 3T3 cells is approx. 0.1 ng/mL, corresponding to a specific activity of approx. 1 x 10^7 units/mg.
- 限制
- 仅限研究用
-
- 状态
- Lyophilized
- 溶解方式
- Reconstitute in 5 mM Tris, pH 7.6 to a concentration of 0.1 - 1.0 mg/mL.
- 缓冲液
- Lyophilized from 5 mM Tris, pH 7.6 with 155 mM NaCl.
- 注意事项
- Avoid repeated freeze/thaw cycles.
- 储存条件
- RT/-20 °C
-
- 抗原
- FGF2 (Fibroblast Growth Factor 2 (Basic) (FGF2))
- 别名
- FGF Basic (FGF2 产品)
- 别名
- BFGF Protein, FGF-2 Protein, FGFB Protein, HBGF-2 Protein, Fgf-2 Protein, Fgfb Protein, bFGF Protein, fibroblast growth factor 2 Protein, fibroblast growth factor 2 (basic) Protein, FGF2 Protein, Fgf2 Protein, fgf2 Protein
- 背景
-
FGF basic is one of 23 known members of the FGF family. Proteins of this family play a central role during prenatal development and postnatal growth and regeneration of a variety of tissues, by promoting cellular proliferation and differentiation. FGF basic is a non-glycosylated heparin binding growth factor that is expressed in the brain, pituitary, kidney, retina, bone, testis, adrenal gland liver, monocytes, epithelial cells and endothelial cells. FGF basic signals through FGFR 1b, 1c, 2c, 3c and 4.
Alternative Names: FGF-2 protein, Prostatropin protein, Fibroblast Growth Factor-basic protein, HBGF-2 protein - 分子量
- 17.2 kDa
- 途径
- RTK signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, C21-Steroid Hormone Metabolic Process, Inositol Metabolic Process, Glycosaminoglycan Metabolic Process, Protein targeting to Nucleus, S100 Proteins
-