IL1A 蛋白
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- 抗原 See all IL1A 蛋白
- IL1A (Interleukin 1 alpha (IL1A))
- 蛋白类型
- Recombinant
- 生物活性
- Active
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宿主
- 小鼠
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资源
- 大肠杆菌（E. Coli）
- 序列
- SAPYTYQSDL RYKLMKLVRQ KFVMNDSLNQ TIYQDVDKHY LSTTWLNDLQ QEVKFDMYAY SSGGDDSKYP VTLKISDSQL FVSAQGEDQP VLLKELPETP KLITGSETDL IFFWKSINSK NYFTSAAYPE LFIATKEQSR VHLARGLPSM TDFQIS
- 产品特性
- Fully biologically active when compared to standard. The ED50 as determined by a cell proliferation assay using murine D10S cells is less than 2 pg/mL, corresponding to a specific activity of > 5.0 x 10^8 IU/mg.
- 纯度
- > 97 % by SDS-PAGE and HPLC analyses.
- 过滤
- 0.2 μm filtered
- 内毒素水平
- < 1 EU/μg of rMuIL-1μ as determined by LAL method.
- Top Product
- Discover our top product IL1A 蛋白
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Interleukin 1 alpha (IL1A) (Active) protein
IL1A 宿主: 小鼠 宿主: 大肠杆菌（E. Coli） Recombinant >95 % as determined by SDS-PAGE Func Active
Interleukin 1 alpha (IL1A) (AA 113-271) proteinIL1A 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Interleukin 1 alpha (IL1A) (AA 113-271) protein (His tag)IL1A 宿主: Cynomolgus 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Interleukin 1 alpha (IL1A) (AA 115-270) protein (His tag)IL1A 宿主: 小鼠 宿主: 大肠杆菌（E. Coli） Recombinant Greater than 95 % as determined by SDS-PAGE WB, ELISA
Interleukin 1 alpha (IL1A) (AA 1-271) protein (GST tag)IL1A 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AA, AP
Interleukin 1 alpha (IL1A) (AA 172-271) protein (GST tag)IL1A 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AA, AP
Interleukin 1 alpha (IL1A) proteinIL1A 宿主: 大鼠 宿主: 大肠杆菌（E. Coli） Recombinant > 95 % as determined by SDS-PAGE
Interleukin 1 alpha (IL1A) proteinIL1A 宿主: 小鼠 宿主: 大肠杆菌（E. Coli） Recombinant > 95 % as determined by SDS-PAGE
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- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in sterile distilled water or aqueous buffer containing 0.1 % BSA to a concentration of 0.1-1.0 mg/mL. Stock solutions should be apportioned into working aliquots and stored at ≤ -20 °C. Further dilutions should be made in appropriate buffered solutions.
- 缓冲液
- Lyophilized from a 0.2 μm filtered solution in PBS, pH 7.4.
- 注意事项
- Avoid repeated freeze/thaw cycles.
- 储存条件
- 4 °C/-20 °C
- 储存方法
- This lyophilized preparation is stable at 2-8 °C, but should be kept at -20 °C for long term storage, preferably desiccated. Upon reconstitution, the preparation is stable for up to one week at 2-8 °C. For maximal stability, apportion the reconstituted preparation into working aliquots and store at -20 °C to -70 °C.
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- 抗原
- IL1A (Interleukin 1 alpha (IL1A))
- 别名
- Interleukin-1 alpha (IL1A 产品)
- 别名
- IL-1A Protein, IL1 Protein, IL1-ALPHA Protein, IL1F1 Protein, IL-6 Protein, Il-1a Protein, IL-1 alpha Protein, IL-1alpha Protein, L1A Protein, interleukin 1 alpha Protein, interleukin 6 Protein, IL1A Protein, IL6 Protein, Il1a Protein
- 背景
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Interleukin-1 alpha (IL-1a) is a non-secreted proinflammatory cytokine produced in a variety of cells including monocytes, tissue macrophages, keratinocytes and other epithelial cells. Both IL-1a and IL-1b binds to the same receptor and has similar if not identical biological properties. These cytokines have a broad range of activities including, stimulation of thymocyte proliferation, by inducing IL-2 release, B-cell maturation and proliferation, mitogenic FGF-like activity and the ability to stimulate the release of prostaglandin and collagenase from synovial cells. However, whereas IL-1b is a secreted cytokine, IL-1a is predominantly a cell-associated cytokine.
Synonyms: Interleukin-1 Alpha, Mouse, - 分子量
- 17.9 kDa, a single non-glycosylated polypeptide chain containing 156 amino acids.
- 途径
- NF-kappaB Signaling, Autophagy, Cancer Immune Checkpoints
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