Interleukin 1 Receptor-Like 1 (IL1RL1) (AA 1-328) 蛋白

ABIN2002075 产品详细信息, 供应商: Log in to see
蛋白名称
  • DER4
  • Fit-1
  • Ly84
  • ST2L
  • St2
  • St2-rs1
  • T1
  • T1/ST2
  • FIT-1
  • IL33R
  • ST2
  • ST2V
  • FIT1
  • interleukin 1 receptor-like 1
  • Il1rl1
  • IL1RL1
产品特性
AA 1-328
6
3
2
2
1
1
1
1
1
1
宿主

15
7
资源
人细胞
5
4
4
2
2
2
1
1
蛋白类型
Recombinant
应用范围
SDS-PAGE (SDS)
选项
Supplier
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产品特性 The recombinant human IL1RL1 consists of 316 amino acids and has a calculated molecular mass of 35.6 kDa. As a result of glycosylation, rh IL1RL1 migrates as an approximately 55-60 kDa band in SDS-PAGE under reducing conditions.

Protein Structure: The secreted isoform of human IL1RL1 (NP_003847.2) (Met 1-Phe 328) with five amino acids (DDDDK) at the C-terminus was expressed and purified.
Predicted N-Term: Lys 19
纯度 > 95 % as determined by SDS-PAGE
内毒素水平 < 1.0 EU per μg of the protein as determined by the LAL method
背景 Synonyms: DER4,FIT-1,IL33R,IL-1 R4,ST2,ST2L,ST2V,T1
分子量 35.6 kDa, 55-60 kDa
NCBI登录号 NP_003847
应用备注 Optimal working dilution should be determined by the investigator.
限制 仅限研究用
状态 Lyophilized
缓冲液 Lyophilized from sterile 50 mM Tris, 100 mM NaCl, pH 8.0
Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween80 are added as protectants before lyophilization.
注意事项 Avoid repeated freeze-thaw cycles. It is recommended that the protein be aliquoted for optimal storage.
储存条件 -20 °C,-80 °C
储存方法 Store it under sterile conditions at -20°C to -80°C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.

Shipping: In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature.
Bulk packages of recombinant proteins are provided as frozen liquid. They are shipped out with blue ice unless customers require otherwise.
有效期 12 months
厂商提供的图像
 image for Interleukin 1 Receptor-Like 1 (IL1RL1) (AA 1-328) protein (ABIN2002075) Interleukin 1 Receptor-Like 1 (IL1RL1) (AA 1-328) protein
背景 Hayakawa, Hayakawa, Kume, Tominaga: "Soluble ST2 blocks interleukin-33 signaling in allergic airway inflammation." in: The Journal of biological chemistry, Vol. 282, Issue 36, pp. 26369-80, 2007 (PubMed).

Sanada, Hakuno, Higgins, Schreiter, McKenzie, Lee: "IL-33 and ST2 comprise a critical biomechanically induced and cardioprotective signaling system." in: The Journal of clinical investigation, Vol. 117, Issue 6, pp. 1538-49, 2007 (PubMed).

Schmitz, Owyang, Oldham, Song, Murphy, McClanahan, Zurawski, Moshrefi, Qin, Li, Gorman, Bazan, Kastelein: "IL-33, an interleukin-1-like cytokine that signals via the IL-1 receptor-related protein ST2 and induces T helper type 2-associated cytokines." in: Immunity, Vol. 23, Issue 5, pp. 479-90, 2005 (PubMed).

Trajkovic, Sweet, Xu: "T1/ST2--an IL-1 receptor-like modulator of immune responses." in: Cytokine & growth factor reviews, Vol. 15, Issue 2-3, pp. 87-95, 2004 (PubMed).

Löhning, Stroehmann, Coyle, Grogan, Lin, Gutierrez-Ramos, Levinson, Radbruch, Kamradt: "T1/ST2 is preferentially expressed on murine Th2 cells, independent of interleukin 4, interleukin 5, and interleukin 10, and important for Th2 effector function." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 95, Issue 12, pp. 6930-5, 1998 (PubMed).