IL1R2 Protein (C-Term, Extracellular Domain)
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- 抗原 See all IL1R2 蛋白
- IL1R2 (Interleukin 1 Receptor, Type II (IL1R2))
- 蛋白类型
- Recombinant
- 生物活性
- Active
- 产品特性
- C-Term, Extracellular Domain
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宿主
- 人
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资源
- HEK-293T Cells
- 特异性
- Optimized DNA sequence encoding Human extracellular domain of human IL-1 receptor type II including a C-terminal His tag was expressed in HEK293 cells.
- 产品特性
- Recombinant IL-R2 (CD121b) is a protein consisting of 342 amino acid residue subunits, due to glycosylation migrates as an approximately 50-60 kDa protein on SDS-PAGE.
- 纯度
- > 97 %, as determined by SDS-PAGE and HPLC
- 过滤
- 0.2 μm filtered
- 内毒素水平
- Endotoxin content was assayed using a LAL gel clot method. Endotoxin level was found to be less than 0.1 ng/µg(1EU/µg).
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- Discover our top product IL1R2 蛋白
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Interleukin 1 Receptor, Type II (IL1R2) (AA 14-343) protein (Fc Tag)
IL1R2 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE
Interleukin 1 Receptor, Type II (IL1R2) protein (His tag)IL1R2 宿主: 人 宿主: HEK-293 Cells Recombinant > 95% as determined by Tris-Bis PAGE,> 95% as determined by HPLC
Interleukin 1 Receptor, Type II (IL1R2) (AA 14-355) protein (His tag)IL1R2 宿主: 小鼠 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Interleukin 1 Receptor, Type II (IL1R2) protein (Fc Tag)IL1R2 宿主: 小鼠 宿主: 人细胞 Recombinant > 95 % as determined by SDS-PAGE
Interleukin 1 Receptor, Type II (IL1R2) (AA 21-120) protein (GST tag)IL1R2 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA
Interleukin 1 Receptor, Type II (IL1R2) (Active) protein (His tag)IL1R2 宿主: 大鼠 宿主: HEK-293 Cells Recombinant > 97 % as determined by SDS-PAGE Active
Interleukin 1 Receptor, Type II (IL1R2) (Active) protein (His tag)IL1R2 宿主: 小鼠 宿主: HEK-293 Cells Recombinant > 95 % as determined by SDS-PAGE Active
Interleukin 1 Receptor, Type II (IL1R2) (Active) protein (Fc Tag)IL1R2 宿主: 小鼠 宿主: HEK-293 Cells Recombinant > 85 % as determined by SDS-PAGE Active
Interleukin 1 Receptor, Type II (IL1R2) (AA 14-343) protein (His tag)Crystallography grade IL1R2 宿主: 人 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
Interleukin 1 Receptor, Type II (IL1R2) (AA 14-355) protein (His tag)Crystallography grade IL1R2 宿主: 小鼠 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
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- 说明
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Recombinant Human IL-1 receptor type activity was measured by its ability to inhibit IL-1b dependent proliferation in mouse helper T cells. The ED50 for this effect is typically 5 µg/mL in the presence of 40 pg/mL of human IL-1b.
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 缓冲液
- PBS solution, pH 7.2, 5 % Trehalose.
- 注意事项
- Avoid repeated freeze/thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- The lyophilized antibody is stable for at least 1 year from date of receipt at -20 °C. Upon reconstitution, this antibody can be stored in working aliquots at - 8 °C for one month, or at -20 °C for six months without detectable loss of activity.
- 有效期
- 12 months
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- 抗原
- IL1R2 (Interleukin 1 Receptor, Type II (IL1R2))
- 别名
- IL1R2 (IL1R2 产品)
- 别名
- CD121b Protein, CDw121b Protein, IL-1R-2 Protein, IL-1RT-2 Protein, IL-1RT2 Protein, IL1R2c Protein, IL1RB Protein, Il1r-2 Protein, IL-1R2 Protein, interleukin 1 receptor type 2 Protein, interleukin 1 receptor, type II Protein, interleukin-like Protein, IL1R2 Protein, Il1r2 Protein, KK34 Protein
- 背景
- IL-6 is produced by many different cell types. The main sources in vivo are stimulated monocytes, fibroblasts, and endothelial cells. Macrophages, T-cells and B-lymphocytes, granulocytes, smooth muscle cells, eosinophils, chondrocytes, osteoblasts, mast cells, glial cells, and keratinocytes also produce IL6 after stimulation. IL6 is a member of a family of cytokines, which also includes LIF, CNTF, Oncostatin M, IL11, and CT-1. All known members of the IL6 cytokine family induce hepatic expression of acute phase proteins. The IL6 receptor is expressed on T-cells, mitogen-activated B-cells, peripheral monocytes and some macrophage- and B-cell derived tumor cell types. It is not expressed in resting B-cells but in resting T-cells. The IL6 receptor is a strongly glycosylated protein of 80 kDa and a length of 449 amino acids. It has been designated CD126.
- UniProt
- P27930
- 途径
- NF-kappaB Signaling
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