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IL12B Protein (His tag)

IL12B 宿主: 人 宿主: Hi-5 Cells Recombinant > 90 % by SDS - PAGE SDS
产品编号 ABIN1098598
发货至: 中国
  • 抗原 See all IL12B 蛋白
    IL12B (Interleukin 12 beta (IL12B))
    蛋白类型
    Recombinant
    宿主
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    资源
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    Hi-5 Cells
    标记
    This IL12B protein is labelled with His tag.
    应用范围
    SDS-PAGE (SDS)
    纯化方法
    purified by using conventional chromatography.
    纯度
    > 90 % by SDS - PAGE
    Top Product
    Discover our top product IL12B 蛋白
  • 说明

    Synonyms: interleukin 12 subuit beta, CLMF, NKSF, CLMF2, NKSF2, IL-12B

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    0.25 mg/ml (determined by Bradford assay)
    缓冲液
    20 mM Tris-HCl buffer (pH 8.0) containing 2 mM DTT, 20% glycerol, 100 mM NaCl, 0.1 MM PMSF
    储存条件
    4 °C
    储存方法
    Avoid repeated freezing and thawing cycles.
  • 抗原
    IL12B (Interleukin 12 beta (IL12B))
    别名
    IL12P40 (IL12B 产品)
    别名
    CLMF Protein, CLMF2 Protein, IL-12B Protein, NKSF Protein, NKSF2 Protein, p40 Protein, Il-12b Protein, Il12p40 Protein, Il-12p40 Protein, Il12 Protein, IL-12p40 Protein, IL-12 Protein, IL-12 p40 Protein, il12b Protein, il12p40.b Protein, zgc:152789 Protein, IL-12.p40 Protein, IL12p40 Protein, IL12B Protein, CLMF p40 Protein, interleukin 12B Protein, interleukin 12b Protein, interleukin 12Ba Protein, IL12B Protein, Il12b Protein, il12ba Protein
    背景
    IL12P40 (interleukin 12 subunit beta), also known as natural killer cell stimulatory factor 2, or cytotoxic lymphocyte maturation factor 2, p40, belongs to the type I cytokine receptor family. This protein is a cytokine that can act as a growth factor for activated T and NK cells, enhance the lytic activity of NK/lymphokine-activated killer cells, and stimulate the production of IFN-gamma by resting PBMC. Interleukin 12 is a disulfide-linked heterodimer composed of the 40 kD cytokine receptor like subunit encoded by this gene, and a 35 kD subunit encoded by IL12A. This cytokine is expressed by activated macrophages that serve as an essential inducer of Th1 cells development. Recombinant human IL12P40 protein, fused to His-tag at C-terminus, was expressed in Hi-5 cell using baculovirus expression system and purified by using conventional chromatography.
    分子量
    35.8kDa (315aa)
    NCBI登录号
    NP_002178
    途径
    JAK/STAT Signaling, Cellular Response to Molecule of Bacterial Origin, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Activated T Cell Proliferation
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