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CCL3 蛋白

CCL3 宿主: 人 宿主: 大肠杆菌(E. Coli) Recombinant > 95 % as determined by reducing SDS-PAGE. Func Active
产品编号 ABIN1096278
发货至: 中国
  • 抗原 See all CCL3 蛋白
    CCL3 (Chemokine (C-C Motif) Ligand 3 (CCL3))
    蛋白类型
    Recombinant
    生物活性
    Active
    宿主
    • 19
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    • 1
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    • 1
    资源
    • 22
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    大肠杆菌(E. Coli)
    应用范围
    Functional Studies (Func)
    原理
    Recombinant Human C-C Motif Chemokine 3/CCL3
    序列
    SLAADTPTAC CFSYTSRQIP QNFIADYFET SSQCSKPGVI FLTKRSRQVC ADPSEEWVQK YVSDLELSA
    产品特性
    Recombinant Human C-C Motif Chemokine 3/CCL3 produced in E. coli is a single non-glycosylated polypeptide chain containing 66 amino acids with a molecular mass of 7.5 kDa.
    纯度
    > 95 % as determined by reducing SDS-PAGE.
    过滤
    0.2 μm filtered
    内毒素水平
    Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test
    Top Product
    Discover our top product CCL3 蛋白
  • 说明

    Biological activity: ED50 is 3-10 ng/mL as determined by the ability of Recombinant CCL3 to chemoattract human CCR5 transfected BaF3 mouse proB cells.

    限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    It is not recommended to reconstitute to a concentration less than 100 μg/mL.
    Dissolve the lyophilized protein in ddH2O.
    Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
    缓冲液
    Lyophilized from a 0.2 μm filtered solution of 20 mM PB, 150 mM NaCl, pH 7.4.
    注意事项
    Always centrifuge tubes before opening. Do not mix by vortex or pipetting.
    储存条件
    4 °C/-20 °C/-80 °C
    储存方法
    Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks.
    Reconstituted protein solution can be stored at 4-7°C for 2-7 days.
    Aliquots of reconstituted samples are stable at < -20°C for 3 months.
    有效期
    3 months
  • 抗原
    CCL3 (Chemokine (C-C Motif) Ligand 3 (CCL3))
    别名
    CCL3/MIP-1 alpha (CCL3 产品)
    别名
    MIP-1alpha Protein, G0S19-1 Protein, LD78ALPHA Protein, MIP-1-alpha Protein, MIP1A Protein, SCYA3 Protein, MIP-1a Protein, Scya3 Protein, AI323804 Protein, LD78alpha Protein, MIP1-(a) Protein, MIP1-alpha Protein, Mip1a Protein, CCL3L1 Protein, CCL3L3 Protein, chemokine (C-C motif) ligand 3 Protein, C-C motif chemokine ligand 3 Protein, CCL3 Protein, Ccl3 Protein
    背景
    Human Chemokine (C-C Motif) Ligand 3 (CCL3) is a small cytokine belonging to the CC chemokine family. CCL3 is primarily expressed in T cells, B cells, and monocytes after antigen or mitogen stimulation. CCL3 exhibits chemoattractive and adhesive effects on lymphocytes. CCL3 exerts multiple effects on hematopoietic precursor cells and inhibits the proliferation of hematopoietic stem cells in vitro as well as in vivo. CCR1 and CCR5 have been identified as functional receptors for CCL3.
    Alternative Names: C-C Motif Chemokine 3, G0/G1 Switch Regulatory Protein 19-1, Macrophage Inflammatory Protein 1-Alpha, MIP-1-Alpha, PAT 464.1, SIS-Beta, Small-Inducible Cytokine A3, Tonsillar Lymphocyte LD78 Alpha Protein, CCL3, G0S19-1, MIP1A, SCYA3
    分子量
    7.5 kDa
    UniProt
    P10147
    途径
    Cellular Response to Molecule of Bacterial Origin, Autophagy
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