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Interleukin 15 (IL15) (AA 49-162), (full length) protein (His tag)

ABIN1047241 产品详细信息, 供应商: Log in to see
蛋白名称
  • IL15
  • AI503618
  • IL-15
  • interleukin 15
  • IL15
  • Il15
产品特性
AA 49-162, full length
39
3
2
2
2
1
1
1
1
1
宿主

73
29
16
4
4
3
3
3
2
1
1
1
1
1
资源
大肠杆菌(E. Coli)
94
17
6
3
1
1
蛋白类型
Recombinant
标记
This IL15 protein is labelled with His tag.
应用范围
ELISA
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序列 NWVNVISDLK KIEDLIQSMH IDATLYTESD VHPSCKVTAM KCFLLELQVI SLESGDASIH DTVENLIILA NNSLSSNGNV TESGCKECEE LEEKNIKEFL QSFVHIVQMF INTS
产品特性 Please inquire if you are interested in this recombinant protein expressed in E. coli, mammalien cells or by baculovirus infection. Be aware about differences in price and lead time.
纯度 90 %
背景 Cytokine that stimulates the proliferation of T-lymphocytes. Stimulation by IL-15 requires interaction of IL-15 with components of IL-2R, including IL-2R beta and probably IL-2R gamma but not IL-2R alpha.
分子量 16.9 kD
UniProt P40933
途径 JAK/STAT Signaling, Glycosaminoglycan Metabolic Process
说明

The yeast protein expression system is the most economical and efficient eukaryotic system for secretion and intracellular expression. A protein expressed by the mammalian cell system is of very high-quality and close to the natural protein. But the low expression level, the high cost of medium and the culture conditions restrict the promotion of mammalian cell expression systems. The yeast protein expression system serve as a eukaryotic system integrate the advantages of the mammalian cell expression system. A protein expressed by yeast system could be modificated such as glycosylation, acylation, phosphorylation and so on to ensure the native protein conformation. It can be used to produce protein material with high added value that is very close to the natural protein. Our proteins produced by yeast expression system has been used as raw materials for downstream preparation of monoclonal antibodies.

限制 仅限研究用
状态 Lyophilized
浓度 0.2-2 mg/mL
缓冲液 Tris-based buffer, 50 % glycerol
注意事项 Repeated freezing and thawing is not recommended. Store working aliquots at 4 °C for up to one week
储存条件 -20 °C
储存方法 Store at -20 °C for extended storage, conserve at -20 °C or -80 °C
厂商提供的图像
SDS-PAGE (SDS) image for Interleukin 15 (IL15) (AA 49-162), (full length) protein (His tag) (ABIN1047241) Interleukin 15 (IL15) (AA 49-162), (full length) protein (His tag)
背景 Tagaya, Kurys, Thies, Losi, Azimi, Hanover, Bamford, Waldmann: "Generation of secretable and nonsecretable interleukin 15 isoforms through alternate usage of signal peptides." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 94, Issue 26, pp. 14444-9, 1998 (PubMed).

Krause, Jandrig, Wernicke, Bulfone-Paus, Pohl, Diamantstein: "Genomic structure and chromosomal localization of the human interleukin 15 gene (IL-15)." in: Cytokine, Vol. 8, Issue 9, pp. 667-74, 1997 (PubMed).

Meazza, Verdiani, Biassoni, Coppolecchia, Gaggero, Orengo, Colombo, Azzarone, Ferrini: "Identification of a novel interleukin-15 (IL-15) transcript isoform generated by alternative splicing in human small cell lung cancer cell lines." in: Oncogene, Vol. 12, Issue 10, pp. 2187-92, 1996 (PubMed).

Grabstein, Eisenman, Shanebeck, Rauch, Srinivasan, Fung, Beers, Richardson, Schoenborn, Ahdieh: "Cloning of a T cell growth factor that interacts with the beta chain of the interleukin-2 receptor." in: Science (New York, N.Y.), Vol. 264, Issue 5161, pp. 965-8, 1994 (PubMed).