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DRAP1 Protein (AA 4-198, partial) (GST tag)

DRAP1 宿主: 人 宿主: 大肠杆菌(E. Coli) Recombinant 90 % ELISA
产品编号 ABIN1046947
发货至: 中国
  • 抗原 See all DRAP1 蛋白
    DRAP1 (DR1-Associated Protein 1 (Negative Cofactor 2 Alpha) (DRAP1))
    蛋白类型
    Recombinant
    产品特性
    AA 4-198, partial
    宿主
    • 5
    • 1
    • 1
    • 1
    资源
    • 2
    • 2
    • 2
    • 1
    • 1
    大肠杆菌(E. Coli)
    标记
    This DRAP1 protein is labelled with GST tag.
    应用范围
    ELISA
    序列
    KKKKYNARFP PARIKKIMQT DEEIGKVAAA VPVIISRALE LFLESLLKKA CQVTQSRNAK TMTTSHLKQC IELEQQFDFL KDLVASVPDM QGDGEDNHMD GDKGARRGRK PGSGGRKNGG MGTKSKDKKL SGTDSEQEDE SEDTDTDGEE ETSQPPPQAS HPSAHFQSPP TPFLPFASTL PLPPAPPGPS APDEE
    产品特性
    Please inquire if you are interested in this recombinant protein expressed in E. coli, mammalien cells or by baculovirus infection. Be aware about differences in price and lead time.
    纯度
    90 %
    Top Product
    Discover our top product DRAP1 蛋白
  • 说明

    The yeast protein expression system is the most economical and efficient eukaryotic system for secretion and intracellular expression. A protein expressed by the mammalian cell system is of very high-quality and close to the natural protein. But the low expression level, the high cost of medium and the culture conditions restrict the promotion of mammalian cell expression systems. The yeast protein expression system serve as a eukaryotic system integrate the advantages of the mammalian cell expression system. A protein expressed by yeast system could be modificated such as glycosylation, acylation, phosphorylation and so on to ensure the native protein conformation. It can be used to produce protein material with high added value that is very close to the natural protein. Our proteins produced by yeast expression system has been used as raw materials for downstream preparation of monoclonal antibodies.

    限制
    仅限研究用
  • 状态
    Lyophilized
    浓度
    0.2-2 mg/mL
    缓冲液
    Tris-based buffer, 50 % glycerol
    注意事项
    Repeated freezing and thawing is not recommended. Store working aliquots at 4 °C for up to one week
    储存条件
    -20 °C
    储存方法
    Store at -20 °C for extended storage, conserve at -20 °C or -80 °C
  • Burkard, Planyavsky, Kaupe, Breitwieser, Bürckstümmer, Bennett, Superti-Furga, Colinge: "Initial characterization of the human central proteome." in: BMC systems biology, Vol. 5, pp. 17, (2011) (PubMed).

    Klejman, Pereira, van Zeeburg, Gilfillan, Meisterernst, Timmers: "NC2alpha interacts with BTAF1 and stimulates its ATP-dependent association with TATA-binding protein." in: Molecular and cellular biology, Vol. 24, Issue 22, pp. 10072-82, (2004) (PubMed).

    Gerhard, Wagner, Feingold, Shenmen, Grouse, Schuler, Klein, Old, Rasooly, Good, Guyer, Peck, Derge, Lipman, Collins, Jang, Sherry, Feolo, Misquitta, Lee, Rotmistrovsky, Greenhut, Schaefer, Buetow et al.: "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). ..." in: Genome research, Vol. 14, Issue 10B, pp. 2121-7, (2004) (PubMed).

    Goppelt, Stelzer, Lottspeich, Meisterernst: "A mechanism for repression of class II gene transcription through specific binding of NC2 to TBP-promoter complexes via heterodimeric histone fold domains." in: The EMBO journal, Vol. 15, Issue 12, pp. 3105-16, (1996) (PubMed).

    Mermelstein, Yeung, Cao, Inostroza, Erdjument-Bromage, Eagelson, Landsman, Levitt, Tempst, Reinberg: "Requirement of a corepressor for Dr1-mediated repression of transcription." in: Genes & development, Vol. 10, Issue 8, pp. 1033-48, (1996) (PubMed).

  • 抗原
    DRAP1 (DR1-Associated Protein 1 (Negative Cofactor 2 Alpha) (DRAP1))
    别名
    Dr1-associated corepressor protein (DRAP1 产品)
    别名
    fb26e10 Protein, zgc:56003 Protein, zgc:77337 Protein, wu:fb26e10 Protein, DRAP1 Protein, 2310074H19Rik Protein, NC2-alpha Protein, DR1-associated protein 1 (negative cofactor 2 alpha) Protein, DR1 associated protein 1 Protein, Dr1 associated protein 1 (negative cofactor 2 alpha) Protein, Dr1 associated protein 1 Protein, drap1 Protein, DRAP1 Protein, Drap1 Protein
    背景
    The association of the DR1/DRAP1 heterodimer with TBP results in a functional repression of both activated and basal transcription of class II genes. This interaction precludes the formation of a transcription-competent complex by inhibiting the association of TFIIA and/or TFIIB with TBP. Can bind to DNA on its own. Ref.1 Ref.2
    分子量
    48.6 kD
    UniProt
    Q14919
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