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Caspase 1 Protein (CASP1) (AA 120-269, partial) (GST tag)

CASP1 宿主: 人 宿主: 大肠杆菌(E. Coli) Recombinant 90 % ELISA
产品编号 ABIN1046768
发货至: 中国
  • 抗原 See all Caspase 1 (CASP1) 蛋白
    Caspase 1 (CASP1)
    蛋白类型
    Recombinant
    产品特性
    AA 120-269, partial
    宿主
    • 9
    • 4
    • 4
    • 3
    • 1
    • 1
    • 1
    资源
    • 14
    • 4
    • 2
    • 1
    • 1
    • 1
    大肠杆菌(E. Coli)
    标记
    This Caspase 1 protein is labelled with GST tag.
    应用范围
    ELISA
    序列
    NPAMPTSSGS EGNVKLCSLE EAQRIWKQKS AEIYPIMDKS SRTRLALIIC NEEFDSIPRR TGAEVDITGM TMLLQNLGYS VDVKKNLTAS DMTTELEAFA HRPEHKTSDS TFLVFMSHGI REGICGKKHS EQVPDILQLN AIFNMLNTKN
    产品特性
    Please inquire if you are interested in this recombinant protein expressed in E. coli, mammalien cells or by baculovirus infection. Be aware about differences in price and lead time.
    纯度
    90 %
    Top Product
    Discover our top product CASP1 蛋白
  • 说明

    The yeast protein expression system is the most economical and efficient eukaryotic system for secretion and intracellular expression. A protein expressed by the mammalian cell system is of very high-quality and close to the natural protein. But the low expression level, the high cost of medium and the culture conditions restrict the promotion of mammalian cell expression systems. The yeast protein expression system serve as a eukaryotic system integrate the advantages of the mammalian cell expression system. A protein expressed by yeast system could be modificated such as glycosylation, acylation, phosphorylation and so on to ensure the native protein conformation. It can be used to produce protein material with high added value that is very close to the natural protein. Our proteins produced by yeast expression system has been used as raw materials for downstream preparation of monoclonal antibodies.

    限制
    仅限研究用
  • 状态
    Lyophilized
    浓度
    0.2-2 mg/mL
    缓冲液
    Tris-based buffer, 50 % glycerol
    注意事项
    Repeated freezing and thawing is not recommended. Store working aliquots at 4 °C for up to one week
    储存条件
    -20 °C
    储存方法
    Store at -20 °C for extended storage, conserve at -20 °C or -80 °C
  • Miller, Ayala, Egger, Raju, Yamin, Ding, Gaffney, Howard, Palyha, Rolando: "Purification and characterization of active human interleukin-1 beta-converting enzyme from THP.1 monocytic cells." in: The Journal of biological chemistry, Vol. 268, Issue 24, pp. 18062-9, (1993) (PubMed).

    Thornberry, Bull, Calaycay, Chapman, Howard, Kostura, Miller, Molineaux, Weidner, Aunins: "A novel heterodimeric cysteine protease is required for interleukin-1 beta processing in monocytes." in: Nature, Vol. 356, Issue 6372, pp. 768-74, (1992) (PubMed).

    Cerretti, Kozlosky, Mosley, Nelson, Van Ness, Greenstreet, March, Kronheim, Druck, Cannizzaro: "Molecular cloning of the interleukin-1 beta converting enzyme." in: Science (New York, N.Y.), Vol. 256, Issue 5053, pp. 97-100, (1992) (PubMed).

  • 抗原
    Caspase 1 (CASP1)
    别名
    Caspase-1 protein (CASP1 产品)
    别名
    ICE Protein, IL1BC Protein, P45 Protein, Il1bc Protein, Ice Protein, CASP1 Protein, CG5370 Protein, DCP-1 Protein, DCP1 Protein, Dcp1 Protein, Dmel\\CG5370 Protein, ccp1 Protein, dcp-1 Protein, dcp1 Protein, l(2)01862 Protein, l(2)02132 Protein, caspase 1 Protein, caspase 1, apoptosis-related cysteine peptidase Protein, caspase 4, apoptosis-related cysteine peptidase Protein, Death caspase-1 Protein, caspase-1 Protein, caspase Protein, caspase recruitment domain-containing protein 16 Protein, caspase 4 Protein, CASP1 Protein, Casp1 Protein, CASP4 Protein, Dcp-1 Protein, Caspase1 Protein, LOC5564196 Protein, LOC451519 Protein
    背景
    Thiol protease that cleaves IL-1 beta between an Asp and an Ala, releasing the mature cytokine which is involved in a variety of inflammatory processes. Important for defense against pathogens. Cleaves and activates sterol regulatory element binding proteins (SREBPs). Can also promote apoptosis.
    分子量
    44.2 kD
    UniProt
    P29466
    途径
    Apoptosis, Interferon-gamma Pathway, Positive Regulation of Endopeptidase Activity, Inflammasome
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