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IKZF1 ELISA试剂盒

(IKAROS Family Zinc Finger 1 (Ikaros) (IKZF1))

This gene encodes a transcription factor that belongs to the family of zinc-finger DNA binding proteins associated with chromatin remodeling. The expression of this protein is restricted to the fetal and adult hemo-lymphopoietic system, and it functions as a regulator of lymphocyte differentiation. Several alternatively spliced transcript variants encoding different isoforms have been described for this gene. All isoforms share a common C-terminal domain, which contains two zinc finger motifs that are required for hetero- or homodimerization, and for interactions with other proteins. The isoforms, however, differ in the number of N-terminal zinc finger motifs that bind DNA and contain the nuclear localization signal, resulting in members with and without DNA-binding properties. Only few isoforms contain the requisite three or more N-terminal zinc motifs that confer high affinity binding to a specific core DNA sequence element in the promoters of target genes. The non-DNA-binding isoforms are largely found in the cytoplasm, and thought to function as dominant negative factors. Overexpression of some dominant-negative isoforms have been associated with B-cell malignancies, such as acute lymphoblastic leukemia (ALL). [provided by RefSeq, May 2011].

recommended

IKZF1 ELISA 试剂盒 (ABIN6967566)

IKZF1 适用: 人 Colorimetric Sandwich ELISA 0.156 ng/mL - 10 ng/mL Plasma, Serum, Tissue Homogenate

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recommended

IKZF1 ELISA 试剂盒 (ABIN1130242)

IKZF1 适用: 小鼠 Colorimetric

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recommended

IKZF1 ELISA 试剂盒 (ABIN1130240)

IKZF1 适用: 小鸡 Colorimetric

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IKZF1 ELISA试剂盒 by 适用

Find IKZF1 ELISA试剂盒 for a variety of species such as anti-Chicken IKZF1, anti-Human IKZF1, anti-Mouse IKZF1. The species listed below are among those available. Click on a link to go to the corresponding products.

IKZF1 ELISA试剂盒 by 检测方法

Find IKZF1 ELISA试剂盒 with a specific 检测方法. The 检测方法 listed below are among those available. Click on a link to go to the corresponding products.

IKZF1 ELISA试剂盒 by Analytical Method

Find IKZF1 ELISA试剂盒 with a specific Analytical Method. The Analytical Method listed below are among those available. Click on a link to go to the corresponding products.

IKZF1 ELISA试剂盒 by 实验类型

Find IKZF1 ELISA试剂盒 with a specific 实验类型. The 实验类型 listed below are among those available. Click on a link to go to the corresponding products.

IKZF1 ELISA试剂盒 by 样本

Find IKZF1 ELISA试剂盒 with a specific 样本. The 样本 listed below are among those available. Click on a link to go to the corresponding products.

Popular IKZF1 ELISA试剂盒

Product

Reactivity

Analytical Method

Validations

Cat. No.

Quantity

Datasheet

IKZF1 ELISA 试剂盒

Reactivity Human

Analytical Method Quantitative Sandwich ELISA

Validations

Cat. No. ABIN6967566

Quantity 96 tests

Datasheet Datasheet

IKZF1 ELISA 试剂盒

Reactivity Mouse

Analytical Method

Validations

Cat. No. ABIN1130242

Quantity 96 tests

Datasheet Datasheet

IKZF1 ELISA 试剂盒

Reactivity Chicken

Analytical Method

Validations

Cat. No. ABIN1130240

Quantity 96 tests

Datasheet Datasheet

Aliases for IKZF1 ELISA试剂盒

IKAROS family zinc finger 1 (IKZF1) ELISA试剂盒
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Aliases for IKZF1 ELISA试剂盒

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