anti-BLK (BLK) 抗体产品概述

Full name:
anti-B Lymphoid Tyrosine Kinase 抗体 (BLK)
在www.antibodies-online.cn可供185 B Lymphoid Tyrosine Kinase (BLK) 抗体的22不同的供货商。 再加上,我们可以发BLK 蛋白 (17)BLK 试剂盒 (7)和数多这个蛋白质的别的产品。 总共220 BLK产品已列进来了。
别名:
bltk, MODY11, si:dkey-33i22.2, zgc:136231

最受欢迎的抗anti-BLK (BLK) 抗体

选择您的来源和应用

抗Mouse (Murine) BLK 抗体:

抗Human BLK 抗体:

抗Rat (Rattus) BLK 抗体:

所有可销售的anti-BLK 抗体

您会转到已过滤好的搜索

引用最多的anti-BLK 抗体

  1. Human Monoclonal BLK Primary Antibody for EIA, FACS - ABIN1105539 : Yang, Ng, Zhao, Hirankarn, Lau, Mok, Chan, Wong, Lee, Mok, Wong, Avihingsanon, Lee, Ho, Lee, Wong, Lau: Population differences in SLE susceptibility genes: STAT4 and BLK, but not PXK, are associated with systemic lupus erythematosus in Hong Kong Chinese. in Genes and immunity 2009 (PubMed)
    Show all 3 references for 1105539

  2. Human Monoclonal BLK Primary Antibody for ICC, FACS - ABIN968983 : Borowiec, Liew, Thompson, Boonyasrisawat, Hu, Mlynarski, El Khattabi, Kim, Marselli, Rich, Krolewski, Bonner-Weir, Sharma, Sale, Mychaleckyj, Kulkarni, Doria: Mutations at the BLK locus linked to maturity onset diabetes of the young and beta-cell dysfunction. in Proceedings of the National Academy of Sciences of the United States of America 2009 (PubMed)
    Show all 3 references for 968983

  3. Human Monoclonal BLK Primary Antibody for ELISA, WB - ABIN560064 : Castillejo-López, Delgado-Vega, Wojcik, Kozyrev, Thavathiru, Wu, Sánchez, Pöllmann, López-Egido, Fineschi, Domínguez, Lu, James, Merrill, Kelly, Kaufman, Moser, Gilkeson, Frostegård, Pons-Estel et al.: Genetic and physical interaction of the B-cell systemic lupus erythematosus-associated genes BANK1 and BLK. ... in Annals of the rheumatic diseases 2011 (PubMed)
    Show all 2 references for 560064

  4. Human Polyclonal BLK Primary Antibody for IHC (p), WB - ABIN392087 : Islam, Rabbani, Larsson, Sanders, Smith: Molecular cloning, characterization, and chromosomal localization of a human lymphoid tyrosine kinase related to murine Blk. in Journal of immunology (Baltimore, Md. : 1950) 1995 (PubMed)
    Show all 2 references for 392087

  5. Mouse (Murine) Polyclonal BLK Primary Antibody for WB - ABIN222964 : Chen, Huang, Wang: Deficiency of Bim in dendritic cells contributes to overactivation of lymphocytes and autoimmunity. in Blood 2007 (PubMed)
    Show all 2 references for 222964

  6. Human Polyclonal BLK Primary Antibody for IHC, ELISA - ABIN1450638 : Drebin, Hartzell, Griffin, Campbell, Niederhuber: Molecular cloning and chromosomal localization of the human homologue of a B-lymphocyte specific protein tyrosine kinase (blk). in Oncogene 1995 (PubMed)
    Show all 2 references for 1450638

  7. Human Monoclonal BLK Primary Antibody for ELISA, IHC - ABIN2869210 : Tretter, Ross, Dordai, Desiderio: Mimicry of pre-B cell receptor signaling by activation of the tyrosine kinase Blk. in The Journal of experimental medicine 2003 (PubMed)

  8. Cow (Bovine) Polyclonal BLK Primary Antibody for WB - ABIN2782461 : Cho, Akbarali, Zerbini, Gu, Boltax, Wang, Oettgen, Zhang, Libermann: Isoforms of the Ets transcription factor NERF/ELF-2 physically interact with AML1 and mediate opposing effects on AML1-mediated transcription of the B cell-specific blk gene. in The Journal of biological chemistry 2004 (PubMed)

更多抗BLK的相互作用对抗体

Mouse (Murine) B Lymphoid Tyrosine Kinase (BLK) interaction partners

  1. our study reveals a previously unappreciated role of reduced BLK (显示 BIK 抗体) expression on extraperitoneal accumulation of B1a cells in mice, as well as the presence of IgG autoantibodies and B1-like cells in humans.

  2. BLK (显示 BIK 抗体) risk alleles confer susceptibility to systemic lupus erythematosus through the dysregulation of a proinflammatory cytokine network.

  3. this study has revealed a previously unappreciated role for Blk (显示 BIK 抗体) in the development and activation of MZ B cells

  4. BCR-ABL (显示 ABL1 抗体) downregulates the Blk (显示 BIK 抗体) gene (encoding B-lymphoid kinase) through c-Myc (显示 MYC 抗体) in leukemic stem cells in chronic myeloid leukemia (显示 BCL11A 抗体)

  5. Data suggest a role of tyrosine kinase (显示 TYRO3 抗体) Btk (显示 BTK 抗体) in the regulation of immune cell unctions and innate inflammatory response.

  6. Analysis of Blk (显示 BIK 抗体)-deficient mice reveals that Blk (显示 BIK 抗体) is required for the development of IL-17 (显示 IL17A 抗体)-producing gammadelta T cell effectors and plays a role in regulating thymus cellularity during ontogeny.

  7. sustained activation of Blk (显示 BIK 抗体) induces responses normally associated with the pre-BCR (显示 BCR 抗体).

  8. Blk (显示 BIK 抗体), being exceptionally highly expressed in the initial segment, is suggested to have a role in the differentiation of this segment of the epididymis.

Human B Lymphoid Tyrosine Kinase (BLK) interaction partners

  1. ur study provides evidence that human BLK is a true proto-oncogene (显示 RAB1A 抗体) capable of inducing tumors, and we demonstrate a novel BLK activity-dependent tumor model suitable for studies of BLK-driven lymphomagenesis and screening of novel BLK inhibitors in vivo.

  2. rs13277113 GA genotype of BLK is more frequent in Systemic Lupus Erythematosus patients and may have a role in low gene expression and increased flares

  3. current meta-analysis suggested that FAM167A-BLK rs2736340 polymorphism is associated with several autoimmune diseases

  4. the SNPs in TNFSF4 and FAM167A-BLK may be involved in asthma and allergic rhinitis gene risk in the Han Chinese cohort.

  5. The systemic lupus erythematosus variant Ala71Thr of BLK severely decreases protein abundance and binding to BANK1 (显示 BANK1 抗体) through impairment of the SH3 domain (显示 ITSN1 抗体) function.

  6. Report a novel BLK gene variant in common variable immunodeficiency-patients that causes suppressed B-cell proliferation and reduced ability of B-cells to elicit antigen-specific CD4 (显示 CD4 抗体)(+) T-cell responses.

  7. A major mechanism underlying the BLK association with autoimmune disease involves lowered thresholds for basal B cell receptor signaling, enhanced B cell-T cell interactions, and altered patterns of isotype switching.

  8. our study reveals a previously unappreciated role of reduced BLK expression on extraperitoneal accumulation of B1a cells in mice, as well as the presence of IgG autoantibodies and B1-like cells in humans.

  9. Results support previous findings that vaiants in the RHOB and FAM167A-BLK genes may be associated with susceptibility to systemic sclerosis.

  10. These results place Blk upstream of the p190RhoGAP (显示 GRLF1 抗体)-RhoA (显示 RHOA 抗体) pathway in Galpha13 (显示 GNA13 抗体)-activated cells, overall representing an opposing signaling module during CXCL12 (显示 CXCL12 抗体)-triggered invasion.

BLK 抗原简介

Antigen Summary

This gene encodes a nonreceptor tyrosine-kinase of the src family of proto-oncogenes that are typically involved in cell proliferation and differentiation. The protein has a role in B-cell receptor signaling and B-cell development. The protein also stimulates insulin synthesis and secretion in response to glucose and enhances the expression of several pancreatic beta-cell transcription factors.

Alternative names and synonyms associated with BLK

  • B lymphoid tyrosine kinase (blk) 抗体
  • B lymphoid tyrosine kinase (BLK) 抗体
  • B lymphoid kinase (Blk) 抗体
  • B lymphoid tyrosine kinase (Blk) 抗体
  • bltk 抗体
  • MODY11 抗体
  • si:dkey-33i22.2 抗体
  • zgc:136231 抗体

Protein level used designations for BLK

B lymphoid kinase , tyrosine-protein kinase Blk , B lymphoid tyrosine kinase , tyrosine-protein kinase Blk-like , b lymphocyte kinase , p55-Blk , BLK nonreceptor tyrosine kinase

GENE ID SPECIES
567764 Danio rerio
100412187 Callithrix jacchus
100442545 Pongo abelii
100479355 Ailuropoda melanoleuca
100559493 Anolis carolinensis
100601418 Nomascus leucogenys
12143 Mus musculus
640 Homo sapiens
486080 Canis lupus familiaris
532587 Bos taurus
364403 Rattus norvegicus
422035 Gallus gallus
anti-BLK (BLK) 抗体 精选生产商
您还需要查找其他产品吗?