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NCOA2 蛋白

(Nuclear Receptor Coactivator 2 (NCOA2))
The NCOA2 gene encodes nuclear receptor coactivator 2, which aids in the function of nuclear hormone receptors. Nuclear hormone receptors are conditional transcription factors that play important roles in various aspects of cell growth, development, and homeostasis by controlling expression of specific genes. Members of the nuclear hormone receptor superfamily, which includes the 5 steroid receptors and class II nuclear receptors (see below), are structurally characterized by 3 distinct domains: an N-terminal transcriptional activation domain, a central DNA-binding domain, and a C-terminal hormone-binding domain. Before the binding of hormone, steroid receptors, which are sometimes called class I of the nuclear hormone receptor family, remain inactive in a complex with heat-shock protein-90 (MIM 140571) and other stress family proteins. Binding of hormone induces critical conformational changes in steroid receptors that cause them to dissociate from the inhibitory complex, bind as homodimers to specific DNA enhancer elements associated with target genes, and modulate that gene's transcription. After binding to enhancer elements, transcription factors require transcriptional coactivator proteins to mediate their stimulation of transcription initiation (Hong et al., 1997 [PubMed 9111344]).[supplied by OMIM, Nov 2010].
NCOA2 Protein (AA 1365-1464) (GST tag) NCOA2 Protein (AA 1365-1464) (GST tag) NCOA2 Protein (AA 1365-1464) (GST tag) (ABIN1312126)

NCOA2 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA

NCOA2 Protein (AA 2-1464) (His tag) NCOA2 Protein (AA 2-1464) (His tag) NCOA2 Protein (AA 2-1464) (His tag) (ABIN3094110)

Crystallography grade NCOA2 宿主: 人 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, ELISA, Crys, SDS

NCOA2 Protein (AA 2-1462) (His tag) NCOA2 Protein (AA 2-1462) (His tag) NCOA2 Protein (AA 2-1462) (His tag) (ABIN3135340)

Crystallography grade NCOA2 宿主: 小鼠 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, ELISA, Crys, SDS

NCOA2 蛋白 by Grade

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NCOA2 蛋白 by Origin

Find NCOA2 蛋白 for a variety of species such as anti-Human NCOA2, anti-Mouse NCOA2, anti-Rat NCOA2. The species listed below are among those available. Click on a link to go to the corresponding products.

NCOA2 蛋白 by Source

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NCOA2 蛋白 by 蛋白类型

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NCOA2 蛋白 by 应用范围

Find NCOA2 蛋白 validated for a specific application such as WB, ELISA, SDS, Crys. Some of the available applications are listed below. Click on a link to go to the corresponding products.

Popular NCOA2 蛋白

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1312126
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Insect Cells
Validations
  • (1)
Cat. No. ABIN3094110
Quantity 1 mg
Datasheet Datasheet
Reactivity Mouse
Source Insect Cells
Validations
  • (1)
Cat. No. ABIN3135340
Quantity 1 mg
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN2750631
Quantity 5 applications
Datasheet Datasheet

Aliases for NCOA2 蛋白

nuclear receptor coactivator 2 (NCOA2) 蛋白
nuclear receptor coactivator 2 (Ncoa2) 蛋白
nuclear receptor coactivator 2 (ncoa2) 蛋白
nuclear receptor coactivator 2 (LOC100089041) 蛋白
nuclear receptor coactivator 2 S homeolog (ncoa2.S) 蛋白
9530095N19 蛋白
bHLHe75 蛋白
bhlhe75 蛋白
D1Ertd433e 蛋白
GRIP-1 蛋白
GRIP1 蛋白
Grip1 蛋白
grip1 蛋白
KAT13C 蛋白
kat13c 蛋白
NCoA-2 蛋白
NCOA2 蛋白
ncoa2-A 蛋白
SRC-2 蛋白
SRC2 蛋白
src2 蛋白
TIF-2 蛋白
TIF2 蛋白
tif2 蛋白
Tif2 蛋白
wu:fc41a10 蛋白
wu:fe26a11 蛋白
XTIF2 蛋白
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