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NCOA2 抗体

(Nuclear Receptor Coactivator 2 (NCOA2))
The NCOA2 gene encodes nuclear receptor coactivator 2, which aids in the function of nuclear hormone receptors. Nuclear hormone receptors are conditional transcription factors that play important roles in various aspects of cell growth, development, and homeostasis by controlling expression of specific genes. Members of the nuclear hormone receptor superfamily, which includes the 5 steroid receptors and class II nuclear receptors (see below), are structurally characterized by 3 distinct domains: an N-terminal transcriptional activation domain, a central DNA-binding domain, and a C-terminal hormone-binding domain. Before the binding of hormone, steroid receptors, which are sometimes called class I of the nuclear hormone receptor family, remain inactive in a complex with heat-shock protein-90 (MIM 140571) and other stress family proteins. Binding of hormone induces critical conformational changes in steroid receptors that cause them to dissociate from the inhibitory complex, bind as homodimers to specific DNA enhancer elements associated with target genes, and modulate that gene's transcription. After binding to enhancer elements, transcription factors require transcriptional coactivator proteins to mediate their stimulation of transcription initiation (Hong et al., 1997 [PubMed 9111344]).[supplied by OMIM, Nov 2010].
NCOA2 抗体  (AA 550-820) NCOA2 抗体  (AA 550-820) NCOA2 抗体 (AA 550-820) (ABIN6144413)

NCOA2 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated

NCOA2 抗体 NCOA2 抗体 NCOA2 抗体 (ABIN7255239)

KO Validated NCOA2 适用: 人, 小鼠, 大鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated

NCOA2 抗体  (N-Term) NCOA2 抗体  (N-Term) NCOA2 抗体 (N-Term) (ABIN2780788)

NCOA2 适用: 人, 小鼠, 大鼠, 兔, 犬, Cow, 豚鼠, 马, Pig WB 宿主: 兔 Polyclonal unconjugated

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NCOA2 抗体 by 适用

Find NCOA2 抗体 for a variety of species such as anti-Human NCOA2, anti-Mouse NCOA2, anti-Rat NCOA2. The species listed below are among those available. Click on a link to go to the corresponding products.

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NCOA2 抗体 by 抗原表位

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Popular NCOA2 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, IHC
Validations
  • (4)
Cat. No. ABIN6144413
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application WB, IHC
Validations
  • (3)
Cat. No. ABIN7255239
Quantity 200 μL
Datasheet Datasheet
Reactivity Cow, Dog, Guinea Pig, Horse, Human, Mouse, Pig, Rabbit, Rat
Application WB
Validations
  • (1)
  • (2)
Cat. No. ABIN2780788
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB
Validations
  • (1)
Cat. No. ABIN6242925
Quantity 200 μL
Datasheet Datasheet
Reactivity Human
Application WB
Validations
  • (1)
Cat. No. ABIN6242927
Quantity 200 μL
Datasheet Datasheet
Reactivity Human, Mouse
Application WB
Validations
  • (1)
Cat. No. ABIN6242926
Quantity 400 μL
Datasheet Datasheet
Reactivity Bat, Dog, Horse, Human, Monkey, Mouse, Pig, Rabbit, Rat
Application WB
Validations
  • (1)
Cat. No. ABIN6742809
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse
Application WB, IHC, IHC (p), IP, IF, PLA
Validations
  • (1)
Cat. No. ABIN2625952
Quantity 50 μL
Datasheet Datasheet
Reactivity Human
Application WB, IHC, ELISA
Validations
  • (2)
Cat. No. ABIN1532157
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro)
Validations
Cat. No. ABIN700810
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, IHC (p), IHC (fro)
Validations
Cat. No. ABIN700812
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, IF (cc), IF (p)
Validations
Cat. No. ABIN907767
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, IF (cc), IF (p)
Validations
Cat. No. ABIN907764
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, IF (cc), IF (p)
Validations
Cat. No. ABIN907768
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, IF (cc), IF (p)
Validations
Cat. No. ABIN2804491
Quantity 100 μL
Datasheet Datasheet

Latest Publications for our NCOA2 抗体

Long, Udy, Dumont: "Hec1 Tail Phosphorylation Differentially Regulates Mammalian Kinetochore Coupling to Polymerizing and Depolymerizing Microtubules." in: Current biology : CB, Vol. 27, Issue 11, pp. 1692-1699.e3, (2018) (PubMed).

Acharya, Finkelstein, Bless, Nettles, Mulac-Jericevic, Conneely, Mani, Tetel: "Estradiol Preferentially Induces Progestin Receptor-A (PR-A) Over PR-B in Cells Expressing Nuclear Receptor Coactivators in the Female Mouse Hypothalamus(1,2,3)." in: eNeuro, Vol. 2, Issue 4, (2015) (PubMed).

Münz, Litterst, Pfitzner: "Interaction of STAT6 with its co-activator SRC-1/NCoA-1 is regulated by dephosphorylation of the latter via PP2A." in: Nucleic acids research, Vol. 39, Issue 8, pp. 3255-66, (2011) (PubMed).

Tognoni, Chadwick, Ackeifi, Tetel: "Nuclear receptor coactivators are coexpressed with steroid receptors and regulated by estradiol in mouse brain." in: Neuroendocrinology, Vol. 94, Issue 1, pp. 49-57, (2011) (PubMed).

Niessen, Balthazart, Ball, Charlier: "Steroid receptor coactivator 2 modulates steroid-dependent male sexual behavior and neuroplasticity in Japanese quail (Coturnix japonica)." in: Journal of neurochemistry, Vol. 119, Issue 3, pp. 579-93, (2011) (PubMed).

Strehl, Nebral, König, Harbott, Strobl, Ratei, Struski, Bielorai, Lessard, Zimmermann, Haas, Izraeli: "ETV6-NCOA2: a novel fusion gene in acute leukemia associated with coexpression of T-lymphoid and myeloid markers and frequent NOTCH1 mutations." in: Clinical cancer research : an official journal of the American Association for Cancer Research, Vol. 14, Issue 4, pp. 977-83, (2008) (PubMed).

Müller, Metzger, Greschik, Bosserhoff, Mercep, Buettner, Schüle: "The transcriptional coactivator FHL2 transmits Rho signals from the cell membrane into the nucleus." in: The EMBO journal, Vol. 21, Issue 4, pp. 736-48, (2002) (PubMed).

Xu, Qiu, DeMayo, Tsai, Tsai, OMalley: "Partial hormone resistance in mice with disruption of the steroid receptor coactivator-1 (SRC-1) gene." in: Science (New York, N.Y.), Vol. 279, Issue 5358, pp. 1922-5, (1998) (PubMed).

Heery, Kalkhoven, Hoare, Parker: "A signature motif in transcriptional co-activators mediates binding to nuclear receptors." in: Nature, Vol. 387, Issue 6634, pp. 733-6, (1997) (PubMed).

Voegel, Heine, Zechel, Chambon, Gronemeyer: "TIF2, a 160 kDa transcriptional mediator for the ligand-dependent activation function AF-2 of nuclear receptors." in: The EMBO journal, Vol. 15, Issue 14, pp. 3667-75, (1996) (PubMed).

Aliases for NCOA2 抗体

nuclear receptor coactivator 2 (NCOA2) 抗体
nuclear receptor coactivator 2 (Ncoa2) 抗体
nuclear receptor coactivator 2 (ncoa2) 抗体
nuclear receptor coactivator 2 (LOC100089041) 抗体
nuclear receptor coactivator 2 S homeolog (ncoa2.S) 抗体
9530095N19 抗体
bHLHe75 抗体
bhlhe75 抗体
D1Ertd433e 抗体
GRIP-1 抗体
GRIP1 抗体
Grip1 抗体
grip1 抗体
KAT13C 抗体
kat13c 抗体
NCoA-2 抗体
NCOA2 抗体
ncoa2-A 抗体
SRC-2 抗体
SRC2 抗体
src2 抗体
TIF-2 抗体
TIF2 抗体
tif2 抗体
Tif2 抗体
wu:fc41a10 抗体
wu:fe26a11 抗体
XTIF2 抗体
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