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MAP3K7 抗体

(Mitogen-Activated Protein Kinase Kinase Kinase 7 (MAP3K7))
The protein encoded by this gene is a member of the serine/threonine protein kinase family. This kinase mediates the signaling transduction induced by TGF beta and morphogenetic protein (BMP), and controls a variety of cell functions including transcription regulation and apoptosis. In response to IL-1, this protein forms a kinase complex including TRAF6, MAP3K7P1/TAB1 and MAP3K7P2/TAB2\; this complex is required for the activation of nuclear factor kappa B. This kinase can also activate MAPK8/JNK, MAP2K4/MKK4, and thus plays a role in the cell response to environmental stresses. Four alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq, Jul 2008].
MAP3K7 抗体  (pThr187) MAP3K7 抗体  (pThr187) MAP3K7 抗体 (pThr187) (ABIN6256492)

MAP3K7 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated

MAP3K7 抗体  (AA 300-470) MAP3K7 抗体  (AA 300-470) MAP3K7 抗体 (AA 300-470) (ABIN6143503)

MAP3K7 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated

MAP3K7 抗体  (AA 1-579) MAP3K7 抗体  (AA 1-579) MAP3K7 抗体 (AA 1-579) (ABIN948522)

MAP3K7 适用: 人 WB, IF, IP 宿主: 兔 Polyclonal unconjugated

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Popular MAP3K7 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human, Mouse, Rat
Application WB, ELISA, IHC, IF, ICC
Validations
  • (10)
Cat. No. ABIN6256492
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, IHC, IF
Validations
  • (7)
Cat. No. ABIN6143503
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, IF, IP
Validations
  • (5)
Cat. No. ABIN948522
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, IF, PLA
Validations
  • (4)
Cat. No. ABIN520689
Quantity 100 μg
Datasheet Datasheet
Reactivity Human, Mouse
Application WB, ELISA, FACS
Validations
  • (4)
Cat. No. ABIN185640
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, IHC
Validations
  • (3)
Cat. No. ABIN7180043
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, RNAi
Validations
  • (3)
Cat. No. ABIN563089
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB, IHC (p)
Validations
  • (3)
  • (2)
Cat. No. ABIN543284
Quantity 400 μL
Datasheet Datasheet
Reactivity Human
Application WB
Validations
  • (3)
Cat. No. ABIN3019512
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, IHC, ICC, FACS
Validations
  • (3)
Cat. No. ABIN5542527
Quantity 0.1 mg
Datasheet Datasheet
Reactivity Human, Mouse
Application WB, IHC (p)
Validations
  • (4)
Cat. No. ABIN657840
Quantity 400 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application WB, ELISA, IHC
Validations
  • (4)
Cat. No. ABIN1848228
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA
Validations
  • (2)
Cat. No. ABIN7180042
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, IHC
Validations
  • (2)
Cat. No. ABIN7181989
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA
Validations
  • (2)
Cat. No. ABIN7138788
Quantity 100 μL
Datasheet Datasheet

Latest Publications for our MAP3K7 抗体

Huang, Chiang, Hung, Hou: "Targeting of TGF-β-activated protein kinase 1 inhibits chemokine (C-C motif) receptor 7 expression, tumor growth and metastasis in breast cancer." in: Oncotarget, Vol. 6, Issue 2, pp. 995-1007, (2015) (PubMed).

Smit, Baas, Kuipers, Korswagen, van de Wetering, Clevers: "Wnt activates the Tak1/Nemo-like kinase pathway." in: The Journal of biological chemistry, Vol. 279, Issue 17, pp. 17232-40, (2004) (PubMed).

Akira, Takeda: "Toll-like receptor signalling." in: Nature reviews. Immunology, Vol. 4, Issue 7, pp. 499-511, (2004) (PubMed).

Ono, Ohtomo, Ninomiya-Tsuji, Tsuchiya: "A dominant negative TAK1 inhibits cellular fibrotic responses induced by TGF-beta." in: Biochemical and biophysical research communications, Vol. 307, Issue 2, pp. 332-7, (2003) (PubMed).

Sakurai, Suzuki, Kawasaki, Nakano, Okazaki, Chino, Doi, Saiki: "Tumor necrosis factor-alpha-induced IKK phosphorylation of NF-kappaB p65 on serine 536 is mediated through the TRAF2, TRAF5, and TAK1 signaling pathway." in: The Journal of biological chemistry, Vol. 278, Issue 38, pp. 36916-23, (2003) (PubMed).

Cheung, Campbell, Nebreda, Cohen: "Feedback control of the protein kinase TAK1 by SAPK2a/p38alpha." in: The EMBO journal, Vol. 22, Issue 21, pp. 5793-805, (2003) (PubMed).

Mungall, Palmer, Sims, Edwards, Ashurst, Wilming, Jones, Horton, Hunt, Scott, Gilbert, Clamp, Bethel, Milne, Ainscough, Almeida, Ambrose, Andrews, Ashwell, Babbage, Bagguley, Bailey, Banerjee, Barker et al.: "The DNA sequence and analysis of human chromosome 6. ..." in: Nature, Vol. 425, Issue 6960, pp. 805-11, (2003) (PubMed).

Jiang, Ninomiya-Tsuji, Qian, Matsumoto, Li: "Interleukin-1 (IL-1) receptor-associated kinase-dependent IL-1-induced signaling complexes phosphorylate TAK1 and TAB2 at the plasma membrane and activate TAK1 in the cytosol." in: Molecular and cellular biology, Vol. 22, Issue 20, pp. 7158-67, (2002) (PubMed).

Dempsey, Sakurai, Sugita, Guesdon: "Alternative splicing and gene structure of the transforming growth factor beta-activated kinase 1." in: Biochimica et biophysica acta, Vol. 1517, Issue 1, pp. 46-52, (2001) (PubMed).

Aliases for MAP3K7 抗体

mitogen-activated protein kinase kinase kinase 7 (map3k7) 抗体
mitogen activated protein kinase kinase kinase 7 (Map3k7) 抗体
mitogen-activated protein kinase kinase kinase 7 (MAP3K7) 抗体
mitogen-activated protein kinase kinase kinase 7 (Map3k7) 抗体
B430101B05 抗体
C87327 抗体
MEKK7 抗体
si:ch211-225h9.1 抗体
Tak1 抗体
TAK1 抗体
TGF1a 抗体
zgc:110612 抗体
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