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GAB2 抗体

(GRB2-Associated Binding Protein 2 (GAB2))
This gene is a member of the GRB2-associated binding protein (GAB) gene family. These proteins contain pleckstrin homology (PH) domain, and bind SHP2 tyrosine phosphatase and GRB2 adapter protein. They act as adapters for transmitting various signals in response to stimuli through cytokine and growth factor receptors, and T- and B-cell antigen receptors. The protein encoded by this gene is the principal activator of phosphatidylinositol-3 kinase in response to activation of the high affinity IgE receptor. Two alternatively spliced transcripts encoding different isoforms have been described for this gene. [provided by RefSeq, Nov 2009].
GAB2 抗体  (pSer159) GAB2 抗体  (pSer159) GAB2 抗体 (pSer159) (ABIN685273)

GAB2 适用: 人, 小鼠, 大鼠 WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated

GAB2 抗体  (pTyr452) GAB2 抗体  (pTyr452) GAB2 抗体 (pTyr452) (ABIN685288)

GAB2 适用: 人, 大鼠 WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated

GAB2 抗体  (AA 273-484) GAB2 抗体  (AA 273-484) GAB2 抗体 (AA 273-484) (ABIN7154436)

GAB2 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated

GAB2 抗体 by Grade

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GAB2 抗体 by 适用

Find GAB2 抗体 for a variety of species such as anti-Human GAB2, anti-Rat GAB2, anti-Mouse GAB2. The species listed below are among those available. Click on a link to go to the corresponding products.

GAB2 抗体 by 应用范围

Find GAB2 抗体 validated for a specific application such as WB, ELISA, IF (cc), IF (p). Some of the available applications are listed below. Click on a link to go to the corresponding products.

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GAB2 抗体 by 抗原表位

Find GAB2 抗体 with a specific epitope. The epitopes listed below are among those available. Click on a link to go to the corresponding products.

GAB2 抗体 by 克隆形成能力

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GAB2 抗体 by 克隆

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GAB2 抗体 by 标记

Find GAB2 抗体 with a specific conjugate such as Biotin, Alexa Fluor 488, Alexa Fluor 555. The conjugates listed below are among those available. Click on a link to go to the corresponding products.

Popular GAB2 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human, Mouse, Rat
Application WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro)
Validations
  • (4)
Cat. No. ABIN685273
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Rat
Application WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro)
Validations
  • (4)
Cat. No. ABIN685288
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, IHC, IF
Validations
  • (4)
Cat. No. ABIN7154436
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, IHC
Validations
  • (3)
Cat. No. ABIN7180017
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, FACS
Validations
  • (2)
  • (2)
Cat. No. ABIN1881358
Quantity 400 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application WB, ELISA, IHC
Validations
  • (3)
Cat. No. ABIN7237045
Quantity 200 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application WB, ELISA, IF (cc), IF (p), IHC (p), FACS, IHC (fro)
Validations
  • (3)
  • (1)
Cat. No. ABIN681178
Quantity 100 μL
Datasheet Datasheet
Reactivity Mouse
Application WB, IHC, IP, ICC
Validations
  • (2)
Cat. No. ABIN7443602
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, IHC
Validations
  • (2)
Cat. No. ABIN7139039
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, IHC
Validations
  • (2)
Cat. No. ABIN7138663
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application WB, ELISA, IHC
Validations
  • (2)
Cat. No. ABIN6261848
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA
Validations
  • (1)
Cat. No. ABIN7180014
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application WB, ELISA
Validations
  • (1)
Cat. No. ABIN6258217
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA
Validations
  • (1)
Cat. No. ABIN7139008
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA
Validations
  • (1)
Cat. No. ABIN7138442
Quantity 100 μL
Datasheet Datasheet

Latest Publications for our GAB2 抗体

Hu, Liao, Xu, Ruan, Gao: "K48-Linked Ubiquitination Contributes to Nicotine-Augmented Bone Marrow-Derived Dendritic-Cell-Mediated Adaptive Immunity." in: Vaccines, Vol. 9, Issue 3, (2021) (PubMed).

You, Xu, Zhang, Chen, Gao: "PYR-41 and Thalidomide Impair Dendritic Cell Cross-Presentation by Inhibiting Myddosome Formation and Attenuating the Endosomal Recruitments of p97 and Sec61 via NF-κB Inactivation." in: Journal of immunology research, Vol. 2018, pp. 5070573, (2018) (PubMed).

Zhan, Xu, Chen, Wang, Yanfeng, Dan, Zhan, Shi: "Decreased expression of Gab2 in patients with temporal lobe epilepsy and pilocarpine-induced rat model." in: Synapse (New York, N.Y.), Vol. 68, Issue 4, pp. 168-77, (2014) (PubMed).

Dunn, Cheung, Agarwalla, Thomas, Zektser, Karst, Boehm, Weir, Berlin, Zou, Getz, Liu, Hirsch, Vazquez, Root, Beroukhim, Drapkin, Hahn: "In vivo multiplexed interrogation of amplified genes identifies GAB2 as an ovarian cancer oncogene." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 111, Issue 3, pp. 1102-7, (2014) (PubMed).

Bentires-Alj, Gil, Chan, Wang, Wang, Imanaka, Harris, Richardson, Neel, Gu: "A role for the scaffolding adapter GAB2 in breast cancer." in: Nature medicine, Vol. 12, Issue 1, pp. 114-21, (2006) (PubMed).

Ek, Andréasson, Hober, Kampf, Pontén, Uhlén, Merz, Borrebaeck: "From gene expression analysis to tissue microarrays: a rational approach to identify therapeutic and diagnostic targets in lymphoid malignancies." in: Molecular & cellular proteomics : MCP, Vol. 5, Issue 6, pp. 1072-81, (2006) (PubMed).

Yamasaki, Nishida, Hibi, Sakuma, Shiina, Takeuchi, Ohnishi, Hirano, Saito: "Docking protein Gab2 is phosphorylated by ZAP-70 and negatively regulates T cell receptor signaling by recruitment of inhibitory molecules." in: The Journal of biological chemistry, Vol. 276, Issue 48, pp. 45175-83, (2001) (PubMed).

Aliases for GAB2 抗体

GRB2 associated binding protein 2 (GAB2) 抗体
GRB2 associated binding protein 2 (gab2) 抗体
GRB2-associated binding protein 2 (Gab2) 抗体
growth factor receptor bound protein 2-associated protein 2 (Gab2) 抗体
AI463667 抗体
D130058I17Rik 抗体
GAB2 抗体
p97 抗体
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