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Fgr 抗体

(Gardner-Rasheed Feline Sarcoma Viral (V-Fgr) Oncogene Homolog (FGR))
This gene is a member of the Src family of protein tyrosine kinases (PTKs). The encoded protein contains N-terminal sites for myristylation and palmitylation, a PTK domain, and SH2 and SH3 domains which are involved in mediating protein-protein interactions with phosphotyrosine-containing and proline-rich motifs, respectively. The protein localizes to plasma membrane ruffles, and functions as a negative regulator of cell migration and adhesion triggered by the beta-2 integrin signal transduction pathway. Infection with Epstein-Barr virus results in the overexpression of this gene. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Jul 2008].
Fgr 抗体  (AA 1-90) Fgr 抗体  (AA 1-90) Fgr 抗体 (AA 1-90) (ABIN560883)

FGR 适用: 人 WB, ELISA, IHC (p) 宿主: 小鼠 Monoclonal 3G10 unconjugated

Fgr 抗体  (N-Term) Fgr 抗体  (N-Term) Fgr 抗体 (N-Term) (ABIN392096)

FGR 适用: 人 WB, IHC (p), IF 宿主: 兔 Polyclonal RB3095 unconjugated

Fgr 抗体  (AA 11-72) Fgr 抗体  (AA 11-72) Fgr 抗体 (AA 11-72) (ABIN7174020)

FGR 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated

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Find Fgr 抗体 for a variety of species such as anti-Human Fgr, anti-Mouse Fgr, anti-Rat Fgr. The species listed below are among those available. Click on a link to go to the corresponding products.

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Fgr 抗体 by 克隆形成能力

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Popular Fgr 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, ELISA, IHC (p)
Validations
  • (6)
Cat. No. ABIN560883
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB, IHC (p), IF
Validations
  • (2)
  • (5)
Cat. No. ABIN392096
Quantity 400 μL
Datasheet Datasheet
Reactivity Human
Application ELISA, IHC, IF
Validations
  • (3)
Cat. No. ABIN7174020
Quantity 100 μg
Datasheet Datasheet
Reactivity Human, Mouse
Application WB, ELISA, IHC
Validations
  • (4)
  • (2)
Cat. No. ABIN969143
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, IHC (p), IF, EIA
Validations
  • (4)
Cat. No. ABIN359981
Quantity 0.4 mL
Datasheet Datasheet
Reactivity Human
Application WB, IP
Validations
  • (2)
Cat. No. ABIN947871
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB
Validations
  • (2)
Cat. No. ABIN515643
Quantity 50 μg
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application WB, ELISA, IF, ICC
Validations
  • (2)
Cat. No. ABIN6258783
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA
Validations
  • (2)
Cat. No. ABIN184643
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB, IHC
Validations
  • (2)
Cat. No. ABIN3022858
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application ELISA, IHC
Validations
  • (1)
Cat. No. ABIN7003539
Quantity 20 μL
Datasheet Datasheet
Reactivity Rat
Application WB
Validations
  • (1)
Cat. No. ABIN6243661
Quantity 400 μL
Datasheet Datasheet
Reactivity Human
Application WB
Validations
  • (1)
Cat. No. ABIN2854681
Quantity 100 μL
Datasheet Datasheet
Reactivity Cow, Human
Application WB
Validations
  • (1)
Cat. No. ABIN6745067
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse
Application WB
Validations
  • (1)
Cat. No. ABIN7260131
Quantity 200 μL
Datasheet Datasheet

Latest Publications for our Fgr 抗体

Brian, Jolicoeur, Guerrero, Nunez, Sychev, Hegre, Sætrom, Habib, Drake, Schwertfeger, Freedman: "Unique-region phosphorylation targets LynA for rapid degradation, tuning its expression and signaling in myeloid cells." in: eLife, Vol. 8, (2020) (PubMed).

Dwyer, Mouchemore, Steer, Sunderland, Sampaio, Greenland, Joyce, Pixley: "Src family kinase expression and subcellular localization in macrophages: implications for their role in CSF-1-induced macrophage migration." in: Journal of leukocyte biology, Vol. 100, Issue 1, pp. 163-75, (2016) (PubMed).

Freedman, Tan, Skrzypczynska, Manz, Sjaastad, Goodridge, Lowell, Weiss: "LynA regulates an inflammation-sensitive signaling checkpoint in macrophages." in: eLife, Vol. 4, (2016) (PubMed).

Henderson, Gonzales, Arora, Choudhary, Trent, Von Hoff, Mousses, Azorsa: "High-throughput RNAi screening identifies a role for TNK1 in growth and survival of pancreatic cancer cells." in: Molecular cancer research : MCR, Vol. 9, Issue 6, pp. 724-32, (2011) (PubMed).

Tatarov, Mitchell, Seywright, Leung, Brunton, Edwards: "SRC family kinase activity is up-regulated in hormone-refractory prostate cancer." in: Clinical cancer research : an official journal of the American Association for Cancer Research, Vol. 15, Issue 10, pp. 3540-9, (2009) (PubMed).

Heneghan, Connaghan-Jones, Miura, Bain: "Coactivator assembly at the promoter: efficient recruitment of SRC2 is coupled to cooperative DNA binding by the progesterone receptor." in: Biochemistry, Vol. 46, Issue 39, pp. 11023-32, (2007) (PubMed).

Zhang, Meng, Chu, Takai, Lowell: "The Src family kinases Hck and Fgr negatively regulate neutrophil and dendritic cell chemokine signaling via PIR-B." in: Immunity, Vol. 22, Issue 2, pp. 235-46, (2005) (PubMed).

Carriero, Franco, Gargiulo, Vocca, Cito, Fontana, Iaccarino, Del Pozzo, Guardiola, Stoppelli: "Inhibition of receptor-dependent urokinase signaling by specific Ser to Glu substitutions." in: Biological chemistry, Vol. 383, Issue 1, pp. 107-13, (2002) (PubMed).

Cordon-Cardo, Richon: "Expression of the retinoblastoma protein is regulated in normal human tissues." in: The American journal of pathology, Vol. 144, Issue 3, pp. 500-10, (1994) (PubMed).

Dunaief, Strober, Guha, Khavari, Alin, Luban, Begemann, Crabtree, Goff: "The retinoblastoma protein and BRG1 form a complex and cooperate to induce cell cycle arrest." in: Cell, Vol. 79, Issue 1, pp. 119-30, (1994) (PubMed).

Aliases for Fgr 抗体

FGR proto-oncogene, Src family tyrosine kinase (FGR) 抗体
FGR proto-oncogene, Src family tyrosine kinase (Fgr) 抗体
c-fgr 抗体
c-src2 抗体
p55-Fgr 抗体
p55c-fgr 抗体
p58-Fgr 抗体
p58c-fgr 抗体
SRC2 抗体
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