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Caspase 4 蛋白

(Caspase 4, Apoptosis-Related Cysteine Peptidase (CASP4))
This gene encodes a protein that is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes composed of a prodomain and a large and small protease subunit. Activation of caspases requires proteolytic processing at conserved internal aspartic residues to generate a heterodimeric enzyme consisting of the large and small subunits. This caspase is able to cleave and activate its own precursor protein, as well as caspase 1 precursor. When overexpressed, this gene induces cell apoptosis. Alternative splicing results in transcript variants encoding distinct isoforms. [provided by RefSeq, Jul 2008].
Caspase 4 Protein (AA 80-270) (His tag) Caspase 4 Protein (AA 80-270) (His tag) Caspase 4 Protein (AA 80-270) (His tag) (ABIN7122167)

CASP4 宿主: 人 宿主: 大肠杆菌(E. Coli) Recombinant Greater than 95 % by SDS-PAGE gel analyses WB, ELISA

Caspase 4 Protein (AA 1-377) (GST tag) Caspase 4 Protein (AA 1-377) (GST tag) Caspase 4 Protein (AA 1-377) (GST tag) (ABIN1348107)

CASP4 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AA, AP

Caspase 4 Protein (AA 81-266) (His tag) Caspase 4 Protein (AA 81-266) (His tag) Caspase 4 Protein (AA 81-266) (His tag) (ABIN3134647)

Crystallography grade CASP4 宿主: 小鼠 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys

Caspase 4 蛋白 by Grade

Find Caspase 4 蛋白 with a specific Grade. The Grade listed below are among those available. Click on a link to go to the corresponding products.

Caspase 4 蛋白 by Origin

Find Caspase 4 蛋白 for a variety of species such as anti-Human Caspase 4, anti-Mouse Caspase 4, anti-Cow Caspase 4. The species listed below are among those available. Click on a link to go to the corresponding products.

Caspase 4 蛋白 by Source

Here you will find Caspase 4 蛋白 proteins organized by several key sources. By clicking on a link, you can access the products. For additional sources, please use our search function.

Caspase 4 蛋白 by 蛋白类型

Here you can find Caspase 4 蛋白 proteins categorized by available protein types. Additional protein types can be located using our search function.

Caspase 4 蛋白 by 应用范围

Find Caspase 4 蛋白 validated for a specific application such as WB, SDS, PC, Imm. Some of the available applications are listed below. Click on a link to go to the corresponding products.

Caspase 4 蛋白 by 生物活性

Find Caspase 4 蛋白 with a specific 生物活性. The 生物活性 listed below are among those available. Click on a link to go to the corresponding products.

Popular Caspase 4 蛋白

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN7122167
Quantity 50 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1348107
Quantity 10 μg
Datasheet Datasheet
Reactivity Mouse
Source Insect Cells
Validations
  • (1)
Cat. No. ABIN3134647
Quantity 1 mg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7394738
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7400240
Quantity 100 μg
Datasheet Datasheet
Reactivity Cow
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7400816
Quantity 100 μg
Datasheet Datasheet
Reactivity Mouse
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7400246
Quantity 100 μg
Datasheet Datasheet
Reactivity Mouse
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7400243
Quantity 100 μg
Datasheet Datasheet
Reactivity Rat
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7423216
Quantity 100 μg
Datasheet Datasheet
Reactivity Cow
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7401236
Quantity 100 μg
Datasheet Datasheet
Reactivity Cow
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN3008667
Quantity 100 μg
Datasheet Datasheet
Reactivity Mouse
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN3008654
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN925028
Quantity 25 U
Datasheet Datasheet

Latest Publications for our Caspase 4 蛋白

Xia, Yang, Bu, Ji, Zhao, Zheng, Lin, Li, Lu: "Differential regulation of c-Jun protein plays an instrumental role in chemoresistance of cancer cells." in: The Journal of biological chemistry, Vol. 288, Issue 27, pp. 19321-9, (2013) (PubMed).

Murakami, Tolstykh, Bao, Niu, Steuer, Bao, Chang, Espiritu, Bansal, Lam, Otto, Sofia, Furman: "Mechanism of activation of PSI-7851 and its diastereoisomer PSI-7977." in: The Journal of biological chemistry, Vol. 285, Issue 45, pp. 34337-47, (2010) (PubMed).

Chen, Xia, Fang, Hawke, Lu: "Caspase-10-mediated heat shock protein 90 beta cleavage promotes UVB irradiation-induced cell apoptosis." in: Molecular and cellular biology, Vol. 29, Issue 13, pp. 3657-64, (2009) (PubMed).

Hasegawa, Yamada, Komiyama, Hayashi, Ishibashi, Sunazuka, Izuhara, Sugahara, Tsuruda, Masuda, Takasu, Tsukasaki, Tomonaga, Kamihira et al.: "A novel natural compound, a cycloanthranilylproline derivative (Fuligocandin B), sensitizes leukemia cells to apoptosis induced by tumor necrosis factor related apoptosis-inducing ligand (TRAIL) ..." in: Blood, Vol. 110, Issue 5, pp. 1664-74, (2007) (PubMed).

Aliases for Caspase 4 蛋白

caspase 4 (CASP4) 蛋白
caspase 4 (Casp4) 蛋白
caspase 4, apoptosis-related cysteine peptidase (CASP4) 蛋白
caspase 4, apoptosis-related cysteine peptidase (Casp4) 蛋白
caspase-4 (LOC100731032) 蛋白
CASP1 蛋白
CASP4 蛋白
Casp4 蛋白
Casp11 蛋白
CASP13 蛋白
Caspl 蛋白
ICE(rel)II 蛋白
ICEREL-II 蛋白
ICH-2 蛋白
ich-3 蛋白
Mih1/TX 蛋白
TX 蛋白
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