anti-BIK (BIK) 抗体产品概述

Full name:
anti-BCL2-Interacting Killer (Apoptosis-Inducing) 抗体 (BIK)
在www.antibodies-online.cn可供120 BCL2-Interacting Killer (Apoptosis-Inducing) (BIK) 抗体的25不同的供货商。 再加上,我们可以发BIK 试剂盒 (5)BIK 蛋白 (5)和数多这个蛋白质的别的产品。 总共145 BIK产品已列进来了。
别名:
BIK, Biklk, BIP1, Blk, BP4, NBK, si:dkey-31f5.6
列出全部抗体 基因 基因ID UniProt
BIK 12124  
BIK 638 Q13323
BIK 114496  

显示所有的来源

显示所有的同义词

最受欢迎的抗anti-BIK (BIK) 抗体

选择您的来源和应用

抗Mouse (Murine) BIK 抗体:

抗Human BIK 抗体:

抗Rat (Rattus) BIK 抗体:

所有可销售的anti-BIK 抗体

您会转到已过滤好的搜索

引用最多的anti-BIK 抗体

  1. Human Polyclonal BIK Primary Antibody for EIA, IHC (p) - ABIN358090 : Nikrad, Johnson, Puthalalath, Coultas, Adams, Kraft: The proteasome inhibitor bortezomib sensitizes cells to killing by death receptor ligand TRAIL via BH3-only proteins Bik and Bim. in Molecular cancer therapeutics 2005 (PubMed)
    Show all 5 references for 358090

  2. Human Monoclonal BIK Primary Antibody for IP, WB - ABIN967566 : Boyd, Gallo, Elangovan, Houghton, Malstrom, Avery, Ebb, Subramanian, Chittenden, Lutz: Bik, a novel death-inducing protein shares a distinct sequence motif with Bcl-2 family proteins and interacts with viral and cellular survival-promoting proteins. in Oncogene 1995 (PubMed)
    Show all 5 references for 967566

  3. Human Polyclonal BIK Primary Antibody for IHC (p), WB - ABIN388114 : Gillissen, Essmann, Graupner, Stärck, Radetzki, Dörken, Schulze-Osthoff, Daniel: Induction of cell death by the BH3-only Bcl-2 homolog Nbk/Bik is mediated by an entirely Bax-dependent mitochondrial pathway. in The EMBO journal 2003 (PubMed)
    Show all 3 references for 388114

  4. Human Polyclonal BIK Primary Antibody for IHC (fro), WB - ABIN2477650 : Unsicker, Stögbauer: Screening of adrenal medullary neuropeptides for putative neurotrophic effects. in International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience 1992 (PubMed)
    Show all 3 references for 2477650

  5. Human Polyclonal BIK Primary Antibody for IHC (p), WB - ABIN389524 : Arena, Martini, Luongo, Capelli, Larocca: Mutations of the BIK gene in human peripheral B-cell lymphomas. in Genes, chromosomes & cancer 2003 (PubMed)
    Show all 2 references for 389524

  6. Human Polyclonal BIK Primary Antibody for WB - ABIN223382 : Chen, Huang, Wang: Deficiency of Bim in dendritic cells contributes to overactivation of lymphocytes and autoimmunity. in Blood 2007 (PubMed)

  7. Human Polyclonal BIK Primary Antibody for IF, WB - ABIN318742 : Mathai, Germain, Shore: BH3-only BIK regulates BAX,BAK-dependent release of Ca2+ from endoplasmic reticulum stores and mitochondrial apoptosis during stress-induced cell death. in The Journal of biological chemistry 2005 (PubMed)

  8. Human Polyclonal BIK Primary Antibody for EIA, IHC (p) - ABIN356832 : Sass, Shembade, Haimerl, Lamoureux, Hashemolhosseini, Tannapfel, Tiegs: TNF pretreatment interferes with mitochondrial apoptosis in the mouse liver by A20-mediated down-regulation of Bax. in Journal of immunology (Baltimore, Md. : 1950) 2007 (PubMed)

更多抗BIK的相互作用对抗体

Mouse (Murine) BCL2-Interacting Killer (Apoptosis-Inducing) (BIK) interaction partners

  1. These studies suggest a link between Bik-mediated caspase (显示 CASP3 抗体) activation and cleavage of viral proteins.

  2. OPN (显示 SPP1 抗体) induces oxidative stress via the involvement of mitochondria and NOX-4 (显示 NOX4 抗体). It may affect mitochondrial morphology and integrity, at least in part, via the involvement of BIK.

  3. Findings identify novel cross talk between autophagy and apoptosis, wherein targeting SQSTM1/p62 (显示 SQSTM1 抗体) converts cytoprotective autophagy to an inefficient form due to cargo loading failure, leading to NBK/Bik accumulation, which triggers apoptosis.

  4. Src (显示 SRC 抗体) tyrosine kinase (显示 TYRO3 抗体) inhibits apoptosis through the Erk1/2 (显示 MAPK1/3 抗体)- dependent degradation of the death accelerator Bik.

  5. The Bik protein, even in combination with Noxa (显示 PMAIP1 抗体), is not a potent suppressor of c-Myc (显示 MYC 抗体)-driven tumourigenesis or critical for chemotherapeutic drug-induced killing of Myc (显示 MYC 抗体)-driven tumours.

  6. BIKDD, a constitutively active mutant form of proapoptotic gene, BIK, effectively induces apoptosis of breast cancer cells and synergizes with lapatinib.

  7. Blk has been mapped to chromosome 15 and overexpressed in transitional B cells of A/WySnJ mice, which demonstrate a cell-autonomous defect leading to excessive apoptosis.

  8. any function of Bik in programmed cell death and stress-induced apoptosis must overlap that of other BH3-only (显示 BBC3 抗体) proteins

  9. Data show that Bik and Bim (显示 BCL2L11 抗体) share the role of eliminating supernumerary germ cells during the first wave of spermatogenesis, a process vital for normal testicular development.

  10. Targeted expression of BikDD, a potent proapoptotic gene driven by CCKAR (显示 CCKAR 抗体)-VISA (显示 MAVS 抗体), exhibited antitumor effects on pancreatic cancer and prolonged survival in multiple xenograft and syngeneic mouse models of pancreatic tumors with virtually no toxicity

Human BCL2-Interacting Killer (Apoptosis-Inducing) (BIK) interaction partners

  1. These studies suggest a link between Bik-mediated caspase (显示 CASP3 抗体) activation and cleavage of viral proteins.

  2. our data demonstrated that suppression of BIK in ER-positive MCF-7 cells prevents the cytotoxic effect of TAM (显示 CCNA1 抗体) and favors a more aggressive phenotype, due to the molecular change of different pathways

  3. HCV RNA replication and release were significantly suppressed in BIK-depleted cells and over-expression of the RNA-dependent RNA polymerase, NS5B, was able to induce BIK expression

  4. BikDDA, a novel mutant of Bik, showed a prolonged half-life and enhanced pro-apoptotic ability in triple-negative breast cancer cells compared with BikDD.

  5. Findings identify novel cross talk between autophagy and apoptosis, wherein targeting SQSTM1/p62 (显示 SQSTM1 抗体) converts cytoprotective autophagy to an inefficient form due to cargo loading failure, leading to NBK/Bik accumulation, which triggers apoptosis.

  6. Authors show that human herpesvirus 4 EBNA2 represses BIK in B-cell lymphoma-derived cell lines and that this host-virus interaction can inhibit the proapoptotic effect of transforming growth factor beta1.

  7. Data suggest BIK expression in tumor cells is not subject to direct regulation by MAP kinase (显示 MAPK1 抗体) signaling; BIK expression appears to be cell-cycle-dependent and increases in G1 cell-cycle arrest which results from inhibition of MAP kinase (显示 MAPK1 抗体) signaling.

  8. BIK/NBK gene expression may have important clinical implications and provide predictive, prognostic or therapeutic marker in breast cancer patients

  9. Src (显示 SRC 抗体) tyrosine kinase (显示 TXK 抗体) inhibits apoptosis through the Erk1/2 (显示 MAPK1/3 抗体)- dependent degradation of the death accelerator Bik.

  10. A previously undescribed indirect epigenetic regulation of BIK in FA-C lymphoblasts is mediated by DeltaNp73, an isoform of p73 (显示 TP73 抗体) lacking its transactivation domain that activates BIK through a proximal element in its promoter.

BIK 抗原简介

Antigen Summary

The protein encoded by this gene shares a critical BH3 domain with other death-promoting proteins, such as BID, BAK, BAD and BAX, that is required for its pro-apoptotic activity, and for interaction with anti-apoptotic members of the BCL2 family, and viral survival-promoting proteins. Since the activity of this protein is suppressed in the presence of survival-promoting proteins, it is suggested as a likely target for anti-apoptotic proteins.

Alternative names and synonyms associated with BIK

  • BCL2-interacting killer (apoptosis-inducing) (BIK) 抗体
  • BCL2-interacting killer (BIK) 抗体
  • BCL2-interacting killer (Bik) 抗体
  • BCL2-interacting killer (apoptosis-inducing) (Bik) 抗体
  • BCL2-interacting killer (apoptosis-inducing) (bik) 抗体
  • BIK 抗体
  • Biklk 抗体
  • BIP1 抗体
  • Blk 抗体
  • BP4 抗体
  • NBK 抗体
  • si:dkey-31f5.6 抗体

Protein level used designations for BIK

BCL2-interacting killer (apoptosis-inducing) , BCL2-interacting killer , apoptosis inducer NBK , bcl-2-interacting killer , bik-like killer protein , apoptosis-inducing NBK

GENE ID SPECIES
470232 Pan troglodytes
711479 Macaca mulatta
790946 Felis catus
12124 Mus musculus
638 Homo sapiens
114496 Rattus norvegicus
564030 Danio rerio
anti-BIK (BIK) 抗体 精选生产商
您还需要查找其他产品吗?