anti-PPP2R4 (PPP2R4) 抗体产品概述

Full name:
anti-Protein Phosphatase 2A Activator, Regulatory Subunit 4 抗体 (PPP2R4)
在www.antibodies-online.cn可供69 Protein Phosphatase 2A Activator, Regulatory Subunit 4 (PPP2R4) 抗体的20不同的供货商。 再加上,我们可以发PPP2R4 蛋白 (9)PPP2R4 试剂盒 (8)和数多这个蛋白质的别的产品。 总共92 PPP2R4产品已列进来了。
2610042B21Rik, 6330556D22Rik, C77440, N28142, PP2A, PR53, PR65, PTPA, PTPRA
列出全部抗体 基因 基因ID UniProt
PPP2R4 51792 Q76MZ3
PPP2R4 5524 Q15257



最受欢迎的抗anti-PPP2R4 (PPP2R4) 抗体


抗Mouse (Murine) PPP2R4 抗体:

抗Human PPP2R4 抗体:

所有可销售的anti-PPP2R4 抗体


引用最多的anti-PPP2R4 抗体

  1. Human Monoclonal PPP2R4 Primary Antibody for EIA, FACS - ABIN1108715 : Yoon, Jun, Park, Jun Yoo, Moon, Soon Baik, Kim, Kim, Kim, Koh, Taek Lee, You: Optimal suppression of protein phosphatase 2A activity is critical for maintenance of human embryonic stem cell self-renewal. in Stem cells (Dayton, Ohio) 2010 (PubMed)
    Show all 2 references for 1108715

  2. Human Monoclonal PPP2R4 Primary Antibody for ICC, FACS - ABIN969557 : Singh, Ye, Bucur, Zhu, Tanya Santos, Rabinovitz, Wei, Gao, Hahn, Khosravi-Far: Protein phosphatase 2A reactivates FOXO3a through a dynamic interplay with 14-3-3 and AKT. in Molecular biology of the cell 2010 (PubMed)
    Show all 2 references for 969557

  3. Human Monoclonal PPP2R4 Primary Antibody for IP, WB - ABIN1042656 : Fellner, Lackner, Hombauer, Piribauer, Mudrak, Zaragoza, Juno, Ogris: A novel and essential mechanism determining specificity and activity of protein phosphatase 2A (PP2A) in vivo. in Genes & development 2003 (PubMed)

  4. Human Polyclonal PPP2R4 Primary Antibody for ELISA, WB - ABIN4347103 : Gushiken, Patel, Liu, Pradhan, Bergeron, Peng, Vijayan: Protein phosphatase 2A negatively regulates integrin alpha(IIb)beta(3) signaling. in The Journal of biological chemistry 2008 (PubMed)


Mouse (Murine) Protein Phosphatase 2A Activator, Regulatory Subunit 4 (PPP2R4) interaction partners

  1. data indicate that PTPalpha (显示 PTPRA 抗体) and FAK (显示 PTK2 抗体), which are enriched in FAs (显示 FAS 抗体), interact with IP3R1 (显示 ITPR1 抗体) at adjacent ER sites to spatially sequester IL-1 (显示 IL1A 抗体)-induced Ca(2 (显示 CA2 抗体)+) signalling

  2. oocyte-specific deletion of Ppp2r1a (显示 PPP2R1A 抗体) led to severe female subfertility without affecting follicle survival, growth, and ovulation.

  3. A Pak1-PP2A-ERM signaling axis mediates F-actin rearrangement and degranulation in mast cells.

  4. PP2A (显示 PPP2R2B 抗体) (Protein Phosphatase 2A(Twins)) counteracts Plk4 (显示 PLK4 抗体) autophosphorylation, thus stabilizing Plk4 (显示 PLK4 抗体) and promoting centriole duplication

  5. PP2A (显示 PPP2R2B 抗体)-A alpha transcriptional regulation is mediated by multiple factors including AP-2alpha (显示 TFAP2A 抗体), CREB (显示 CREB1 抗体), ETS-1 (显示 ETS1 抗体), and SP-1 (显示 SP1 抗体)

  6. Data show that DSB promote PP2A to associate with Ku 70 and Ku 86.

  7. protein phosphatase 2A overexpression in NIH 3T3 cells

  8. T-cell receptor (TCR)-dependent tyrosine phosphorylation may be the mechanism by which the regulatory subunit of PP2A (显示 PPP2R2B 抗体) prevents the inhibitory function of CTLA-4 (显示 CTLA4 抗体), before TCR-CTLA-4 (显示 CTLA4 抗体) coligation.

  9. PP-2A regulation of paxillin (显示 PXN 抗体) phosphorylation may have a role in controlling tumor cell adherence and motility.

  10. PP2A (显示 PPP2R2B 抗体) may contribute to melanoma cell radioresistance: the truncated isoform of the PP2A (显示 PPP2R2B 抗体) B56gamma regulatory subunit reduces irradiation-induced Mdm2 (显示 MDM2 抗体) phosphorylation

Human Protein Phosphatase 2A Activator, Regulatory Subunit 4 (PPP2R4) interaction partners

  1. The results of this study demonstrated that HBx of hepatitis B virus impairs interferon (显示 IFNA 抗体) signaling via increased expression of SOCS3 (显示 SOCS3 抗体) and PP2A.

  2. The current study describes a novel pathogenic mechanism of action for human polyomavirus 6 small tumor (sT) antigen which involves binding to protein phosphatase 2A (PP2A) via its WFG motif and zinc binding sites for activation of PP2A's downstream oncogenic pathways (MEK (显示 MAP2K1 抗体)/ERK (显示 EPHB2 抗体)/c-Jun (显示 JUN 抗体)).

  3. The aim of this review is to shed light on the role of four different phosphatases (PTEN (显示 PTEN 抗体), PP2A, CDC25 (显示 RASGRF1 抗体) and DUSP1 (显示 DUSP1 抗体)) in five different solid tumors (breast cancer, lung cancer, pancreatic cancer, prostate cancer and ovarian cancer), in order to better understand the most frequent and aggressive primary cancer of the central nervous system, glioblastoma.

  4. Oncoprotein CIP2A (显示 KIAA1524 抗体) is stabilized via interaction with tumor suppressor PP2A/B56

  5. Such effect by miR (显示 MLXIP 抗体)-429 was again abolished with AMPKalpha1 (显示 PRKAA1 抗体) silence or mutation. Together, we propose that PP2A-c silence by miR (显示 MLXIP 抗体)-429 activates AMPK (显示 PRKAA1 抗体) and protects osteoblastic cells from Dex.

  6. PTPalpha (显示 PTPRA 抗体) is identified as a novel substrate of N-Acetylglucosaminyltransferase V (GnT-V (显示 MGAT5 抗体)) and could be a factor regulating promotion of migration in breast cancer cells

  7. This article reviews the involvement of PP2A in the regulation of three cell signaling pathways: wnt (显示 WNT2 抗体), mTOR (显示 FRAP1 抗体) and MAP kinase (显示 MAPK1 抗体), as well as the G1-->S transition, DNA synthesis and mitotic initiation. These processes are all crucial for proper cell survival and proliferation and are often deregulated in cancer and other diseases. [review]

  8. PP2A-B55 (显示 MINK1 抗体) substrates were identified and assigned their temporal order in mitotic exit.

  9. Our results provide a novel mechanistic insight into the activation of Myc (显示 MYC 抗体) by 27-HC via transcriptional repression of PP2A, SCP1 (显示 SYCP1 抗体) and FBW7 (显示 FBXW7 抗体) to increase Myc (显示 MYC 抗体) protein stability in breast cancer cells.

  10. Data show that the truncation promotes glycogen synthase kinase-3beta (GSK-3beta (显示 GSK3b 抗体)) nuclear translocation and enhances its interaction with protein phosphatase 2A (PP2A), leading to dephosphorylation.

PPP2R4 抗原简介

Antigen Summary

Protein phosphatase 2A is one of the four major Ser/Thr phosphatases and is implicated in the negative control of cell growth and division. Protein phosphatase 2A holoenzymes are heterotrimeric proteins composed of a structural subunit A, a catalytic subunit C, and a regulatory subunit B. The regulatory subunit is encoded by a diverse set of genes that have been grouped into the B/PR55, B'/PR61, and B''/PR72 families. These different regulatory subunits confer distinct enzymatic specificities and intracellular localizations to the holozenzyme. The product of this gene belongs to the B' family. This gene encodes a specific phosphotyrosyl phosphatase activator of the dimeric form of protein phosphatase 2A. Alternative splicing results in multiple transcript variants encoding different isoforms.

Alternative names and synonyms associated with PPP2R4

  • protein phosphatase 2 (formerly 2A), regulatory subunit A (PR 65), alpha isoform (Ppp2r1a) 抗体
  • protein phosphatase 2A activator, regulatory subunit 4 (PPP2R4) 抗体
  • protein phosphatase 2A, regulatory subunit B (PR 53) (Ppp2r4) 抗体
  • 2610042B21Rik 抗体
  • 6330556D22Rik 抗体
  • C77440 抗体
  • N28142 抗体
  • PP2A 抗体
  • PR53 抗体
  • PR65 抗体
  • PTPA 抗体
  • PTPRA 抗体

Protein level used designations for PPP2R4

PP2A subunit A isoform PR65-alpha , PP2A subunit A isoform R1-alpha , protein phosphatase PP2A , serine/threonine protein phosphatase A subunit type 2A , serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform , PP2A phosphatase activator , PP2A subunit B' isoform PR53 , phosphotyrosyl phosphatase activator , protein phosphatase 2A, regulatory subunit B' (PR 53) , serine/threonine-protein phosphatase 2A activator , serine/threonine-protein phosphatase 2A regulatory subunit B' , PP2A, subunit B', PR53 isoform , PTPA , serine/threonine-protein phosphatase 2A regulatory subunit 4 , protein tyrosine phosphatase, receptor type, A

51792 Mus musculus
5524 Homo sapiens
514460 Bos taurus
100009404 Oryctolagus cuniculus
110854 Mus musculus
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