anti-MTOR (FRAP1) 抗体产品概述

Full name:
anti-Mechanistic Target of Rapamycin (serine/threonine Kinase) 抗体 (FRAP1)
在www.antibodies-online.cn可供368 Mechanistic Target of Rapamycin (serine/threonine Kinase) (FRAP1) 抗体的36不同的供货商。 再加上,我们可以发MTOR 试剂盒 (45)MTOR 蛋白 (4)和数多这个蛋白质的别的产品。 总共432 MTOR产品已列进来了。
别名:
2610315D21Rik, AI327068, flat, FRAP, frap1, FRAP2, RAFT1, RAPT1, tor, wu:fc22h08

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引用最多的anti-MTOR 抗体

  1. Human Polyclonal MTOR Primary Antibody for EIA, IHC (p) - ABIN117909 : Chase, Rao, Hofmann, Chang-Hasnain: 1550 nm high contrast grating VCSEL. in Optics express 2010 (PubMed)
    Show all 9 references for 117909

  2. Dog (Canine) Polyclonal MTOR Primary Antibody for EIA, WB - ABIN401320 : McMahon, Choi, Lin, Abraham, Lawrence: The rapamycin-binding domain governs substrate selectivity by the mammalian target of rapamycin. in Molecular and cellular biology 2002 (PubMed)
    Show all 6 references for 401320

  3. Chicken Monoclonal MTOR Primary Antibody for IF, WB - ABIN968383 : Alarcon, Cardenas, Heitman: Mammalian RAFT1 kinase domain provides rapamycin-sensitive TOR function in yeast. in Genes & development 1996 (PubMed)
    Show all 5 references for 968383

  4. Human Polyclonal MTOR Primary Antibody for IF, IHC (p) - ABIN196962 : Holz, Blenis: Identification of S6 kinase 1 as a novel mammalian target of rapamycin (mTOR)-phosphorylating kinase. in The Journal of biological chemistry 2005 (PubMed)
    Show all 4 references for 196962

  5. Human Polyclonal MTOR Primary Antibody for IF (p), IHC (p) - ABIN676403 : Li, Liu, Wang, Sun, Ding, Sun, Han, Wang: Follistatin could promote the proliferation of duck primary myoblasts by activating PI3K/Akt/mTOR signalling. in Bioscience reports 2014 (PubMed)
    Show all 4 references for 676403

  6. Human Polyclonal MTOR Primary Antibody for ELISA, WB - ABIN1532744 : Brown, Albers, Shin, Ichikawa, Keith, Lane, Schreiber: A mammalian protein targeted by G1-arresting rapamycin-receptor complex. in Nature 1994 (PubMed)
    Show all 3 references for 1532744

  7. Human Polyclonal MTOR Primary Antibody for ELISA, WB - ABIN1531715 : Onyango, Lubyova, Gardellin, Kurzbauer, Weith: Molecular cloning and expression analysis of five novel genes in chromosome 1p36. in Genomics 1998 (PubMed)
    Show all 3 references for 1531715

  8. Human Polyclonal MTOR Primary Antibody for IF (p), IHC (p) - ABIN747158 : Yang, Wang, Wang, Zhang, Zhang, Lu, Wang: mTOR is involved in 17?-estradiol-induced, cultured immature boar Sertoli cell proliferation via regulating the expression of SKP2, CCND1, and CCNE1. in Molecular reproduction and development 2015 (PubMed)
    Show all 2 references for 747158

  9. Human Polyclonal MTOR Primary Antibody for IF, IHC (p) - ABIN390217 : Cao, Dong, Meng, Liu, Liao, Liu: MiR-511 inhibits growth and metastasis of human hepatocellular carcinoma cells by targeting PIK3R3. in Tumour biology 2015 (PubMed)

  10. Human Polyclonal MTOR Primary Antibody for IHC, ELISA - ABIN1531910 : Luo, Yoneda, Ohmori, Sasaki, Shimbo, Eto, Kato, Miyano, Kobayashi, Sasahira, Chihara, Kuniyasu: Cancer usurps skeletal muscle as an energy repository. in Cancer research 2014 (PubMed)

更多抗MTOR的相互作用对抗体

Horse (Equine) Mechanistic Target of Rapamycin (serine/threonine Kinase) (FRAP1) interaction partners

Human Mechanistic Target of Rapamycin (serine/threonine Kinase) (FRAP1) interaction partners

  1. High mTOR expression is associated with melanoma.

  2. Studies indicate that understanding mTOR network circuitry will provide insight into its deregulation in diabetes, cancer, and cardiovascular disease, but modeling in silico to elucidate how insulin (显示 INS 抗体) activates mTORC2 (显示 CRTC2 抗体) remains poorly defined.

  3. Mutated MTOR identified in central nervous system germ cell tumors upregulated phosphorylation of the AKT (显示 AKT1 抗体) pathway proteins

  4. Findings demonstrate that the Akt (显示 AKT1 抗体)/mTOR pathway is upregulated in verrucous carcinoma of the oral cavity , indicating a role for this pathway in the development and progression of this malignancy.

  5. IL-37 regulates autophagy in SMMC-7721 and Huh-7 cells via inhibition of the PI3K (显示 PIK3CA 抗体)/AKT (显示 AKT1 抗体)/mTOR signaling pathway.

  6. A nutrient-sensitive mTOR/ChREBP (显示 MLXIPL 抗体) regulated transcriptional network could be a novel target to improve beta cell survival and glucose homeostasis in diabetes.

  7. Interleukin-37 induces apoptosis and autophagy of SMMC-7721 cells by inhibiting phosphorylation of mTOR.

  8. Abnormal mTOR activity may contribute to chemotherapy resistance, while it may also be effectively targeted via molecular means and/or development of specific pharmacological inhibitors.

  9. CXCR2 (显示 CXCR2 抗体) preferentially supports the maintenance of human pluripotent stem cell characteristics as well as facilitates ectodermal differentiation after the commitment to differentiation, and the mechanism might be associated with mTOR, beta-catenin (显示 CTNNB1 抗体), and hTERT activities.

  10. Data show that mTOR protein forms a complex with Raptor (显示 RPTOR 抗体) and estrogen receptor-alpha (ERalpha (显示 ESR1 抗体)).

Mouse (Murine) Mechanistic Target of Rapamycin (serine/threonine Kinase) (FRAP1) interaction partners

  1. results establish a novel mechanism by which mTORC1 regulates Th1 differentiation, through control of T-bet phosphorylation

  2. Tsc2 (显示 TSC2 抗体)-mTOR signaling in mesenchyme is essential for the maintenance of renal structure and for lung alveolarization.

  3. This study suggests that mTOR activity in hepatocytes decreases hepatic vulnerability to injury through a mechanism dependent on NF-kappaB (显示 NFKB1 抗体) proinflammatory cytokine signaling pathway in both normal and steatotic liver.

  4. TSC1 (显示 TSC1 抗体)/TSC2 (显示 TSC2 抗体) complex upregulation of OPN (显示 SPP1 抗体) expression is mediated by transcription factor SOX9 (显示 SOX9 抗体) in an mTOR-independent manner. Moreover, ablation of OPN (显示 SPP1 抗体) by deficient TSC1 (显示 TSC1 抗体)/TSC2 (显示 TSC2 抗体) complex contributed to inactivation of AKT (显示 AKT1 抗体) in TSC (显示 SLC12A3 抗体) cells

  5. Suppressing mTOR signaling in in vitro-expanded Vgamma4 gammadelta T cells via the mechanistic inhibitor rapamycin enhanced their cytotoxicity against multiple tumor cell lines, and these cells performed better tumor-suppressing effects upon adoptive therapy. mTOR signaling plays an important role in the cytotoxic effector function of gammadelta T cells.

  6. A nutrient-sensitive mTOR/ChREBP (显示 MLXIPL 抗体) regulated transcriptional network could be a novel target to improve beta cell survival and glucose homeostasis in diabetes.

  7. Mycobacterium ulcerans mycolactone acts as an inhibitor of the mechanistic Target of Rapamycin (mTOR) signaling pathway by interfering with the assembly of the two distinct mTOR protein complexes mTORC1 and mTORC2 (显示 CRTC2 抗体)

  8. High mTOR expression is associated with pituitary tumor development.

  9. mTOR protein signaling promotes stable epidermal adhesion in the skin and accelerates wound healing.

  10. mTOR-sensitive perturbation of smooth muscle cell mechanosensing contributes to elastin (显示 ELN 抗体) aortopathy.

Zebrafish Mechanistic Target of Rapamycin (serine/threonine Kinase) (FRAP1) interaction partners

  1. This study reveals the dramatic rescue effects of L-leucine stimulation of mTORC1 in RBS (显示 ESCO2 抗体) cells and supports that normal gene expression and translation requires ESCO2 (显示 ESCO2 抗体) function.

  2. By inhibiting mTOR signaling via Fbxw7 (显示 FBXW7 抗体), the amount of myelination during development is reduced.

  3. Apc mutations activate mechanistic target of rapamycin complex 1 in mice and zebrafish

  4. In our zebrafish model, autophagy induction does not depend on inhibition of the Tor pathway or activation of Tp53 (显示 TP53 抗体).

  5. TOR signaling is a common pathological pathway that can be leveraged for therapeutic benefits in cardiomyopathies of different origins.

  6. in addition to regulating cell growth and proliferation, TOR signaling controls the developmental program guiding epithelial morphogenesis in the intestine

Pig (Porcine) Mechanistic Target of Rapamycin (serine/threonine Kinase) (FRAP1) interaction partners

  1. The immunoprecipitation results also showed that high AA concentrations significantly increased the interaction of mTOR and PPARg (显示 PPARG 抗体). In summary, PPARg (显示 PPARG 抗体) plays an important role in the regulation of IGF-1 (显示 IGF1 抗体) secretion and gene expression in response to dietary protein.

  2. These results indicate glycine enhances muscle protein mass under an inflammatory condition. The beneficial roles of glycine on the muscle are closely associated with maintaining Akt (显示 AKT1 抗体)-mTOR-FOXO1 (显示 FOXO1 抗体) signaling and suppressing the activation of TLR4 (显示 TLR4 抗体) and/or NOD2 (显示 NOD2 抗体) signaling pathways.

  3. Data show that the amount of proteins related to mechanistic target of rapamycin (mTOR) signaling pathways decreased along crypt-villus axis (CVA).

  4. AMPK (显示 PRKAA1 抗体)-mTOR-autophagy signaling is altered by intrauterine growth restriction in newborn piglets.

  5. Uroguanylin (显示 GUCA2B 抗体) modulates (Na++K+)ATPase (显示 ATP1A1 抗体) in a proximal tubule cells via cGMP/protein kinase (显示 CDK7 抗体) G, cAMP/protein kinase A, and mTOR pathways.

  6. mTOR is involved in 17beta-estradiol-induced, cultured immature boar Sertoli cell proliferation via regulating the expression of SKP2, CCND1 (显示 CCND1 抗体), and CCNE1 (显示 CCNE1 抗体).

  7. L-Glutamine (显示 GFPT2 抗体) enhances enterocyte growth via activation of the mTOR.

  8. Arg, Leu, and Gln act coordinately to stimulate proliferation of pTr (显示 PTCHD3 抗体) cells through activation of the MTOR-RPS6K-RPS6 (显示 RPS6 抗体)-EIF4EBP1 (显示 EIF4EBP1 抗体) signal transduction pathway.

  9. Data indicate that the expression of MAP1LC3A (显示 MAP1LC3A 抗体), B and autophagy-associated genes (ATG5 (显示 ATG5 抗体), mTOR, Beclin-1 (显示 BECN1 抗体)) was increased in normal pigs, while decreased in miniature pigs.

  10. Biochemical, cellular, and molecular data suggest that L-arginine (显示 GATM 抗体) stimulates mTOR biosynthesis, mTOR signaling, and overall protein biosynthesis/turnover in placental/trophoblast and blastocyst/ectoderm cells thereby enhancing cell proliferation.

Cow (Bovine) Mechanistic Target of Rapamycin (serine/threonine Kinase) (FRAP1) interaction partners

  1. These findings suggest that mTOR is involved in the control of the expression of multiple genes in cattle, which may be triggered by the luteinizing hormone surge.

  2. 14-3-3gamma (显示 YWHAG 抗体) affects mTOR protein pathway and regulates lactogenesis in dairy cow mammary epithelial cells.

  3. Methionine promoted casein synthesis, and this may be mediated by enhanced intracellular substrate availability and by activating JAK2 (显示 JAK2 抗体)-STAT5 (显示 STAT5A 抗体) and mTOR signaling pathways.

  4. Insulin (显示 INS 抗体)-induced activation of phosphoinositide 3-kinase~mTOR pathway up-regulates tau protein via acceleration of protein synthesis in adrenal chromaffin cells, promoting neurite-like process outgrowth.

  5. IGF-I (显示 IGF1 抗体) down-regulated functional IGF-I receptor (显示 IGF1R 抗体) via GSK-3beta (显示 GSK3b 抗体) inhibition and mTOR activation; constitutive activity of GSK-3beta (显示 GSK3b 抗体) maintained IGF-I receptor (显示 IGF1R 抗体) level in nonstimulated cells.

  6. stimulation of mammary protein synthesis by amino acids and its enhancement by a combination of the lactogenic hormones hydrocortisone, insulin (显示 INS 抗体), and prolactin (显示 PRL 抗体) were associated with increased phosphorylation of the mTOR substrates

  7. data demonstrate that hypoxia-induced adventitial fibroblast proliferation requires activation and interaction of PI3K, Akt (显示 AKT1 抗体), mTOR, p70S6K (显示 RPS6KB1 抗体), and ERK1/2 (显示 MAPK1/3 抗体).

  8. prostaglandin F2alpha phosphorylates TSC2 (显示 TSC2 抗体) and activates mTOR and ribosomal protein S6 (显示 RPS6 抗体) kinase (显示 RPS6KB1 抗体) signaling in an AKT (显示 AKT1 抗体)-independent manner

  9. mTOR links IGF-I (显示 IGF1 抗体) and EGF (显示 EGF 抗体) signaling in inhibiting the autophagy pathways.

MTOR (FRAP1) 抗原简介

Antigen Summary

The protein encoded by this gene belongs to a family of phosphatidylinositol kinase-related kinases. These kinases mediate cellular responses to stresses such as DNA damage and nutrient deprivation. This protein acts as the target for the cell-cycle arrest and immunosuppressive effects of the FKBP12-rapamycin complex. The ANGPTL7 gene is located in an intron of this gene.

Alternative names and synonyms associated with MTOR (FRAP1)

  • mechanistic target of rapamycin (serine/threonine kinase) (MTOR) 抗体
  • mechanistic target of rapamycin (serine/threonine kinase) (Mtor) 抗体
  • mechanistic target of rapamycin (serine/threonine kinase) (mtor) 抗体
  • 2610315D21Rik 抗体
  • AI327068 抗体
  • flat 抗体
  • FRAP 抗体
  • frap1 抗体
  • FRAP2 抗体
  • RAFT1 抗体
  • RAPT1 抗体
  • tor 抗体
  • wu:fc22h08 抗体

Protein level used designations for FRAP1

FK506 binding protein 12-rapamycin associated protein 1 , FK506 binding protein 12-rapamycin associated protein 2 , FK506-binding protein 12-rapamycin complex-associated protein 1 , FKBP-rapamycin associated protein , FKBP12-rapamycin complex-associated protein 1 , mammalian target of rapamycin , rapamycin and FKBP12 target 1 , rapamycin associated protein FRAP2 , rapamycin target protein 1 , serine/threonine-protein kinase mTOR , FKBP-rapamycin associated protein (FRAP) , FKBP-rapamycin-associated protein FRAP , FKBP12-rapamycin complex-associated protein , angiopoietin-like factor CDT6 , RAPT1 , rapamycin and FKBP12 target-1 protein , target of rapamycin

GENE ID SPECIES
100051341 Equus caballus
419455 Gallus gallus
2475 Homo sapiens
56717 Mus musculus
56718 Rattus norvegicus
324254 Danio rerio
478232 Canis lupus familiaris
100127359 Sus scrofa
100139219 Bos taurus
100860902 Capra hircus
100271659 Ovis aries
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