anti-MAPKAP1 (MAPKAP1) 抗体产品概述

Full name:
anti-Mitogen-Activated Protein Kinase Associated Protein 1 抗体 (MAPKAP1)
在www.antibodies-online.cn可供85 Mitogen-Activated Protein Kinase Associated Protein 1 (MAPKAP1) 抗体的21不同的供货商。 再加上,我们可以发MAPKAP1 试剂盒 (5)MAPKAP1 蛋白 (4)和数多这个蛋白质的别的产品。 总共103 MAPKAP1产品已列进来了。
别名:
AI591529, CG10105, D230039K05Rik, Dmel\\CG10105, dSin1, im:7143088, JC310, MAPKAP1, MGC53034, MIP1, si:ch73-242f23.1, Sin1, SIN1b, SIN1g

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  1. Human Polyclonal MAPKAP1 Primary Antibody for ICC, IF - ABIN258134 : Huang, Wu, Wu, Manning: Signaling events downstream of mammalian target of rapamycin complex 2 are attenuated in cells and tumors deficient for the tuberous sclerosis complex tumor suppressors. in Cancer research 2009 (PubMed)
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  2. Human Polyclonal MAPKAP1 Primary Antibody for IHC (p), WB - ABIN2475490 : Xia, Gu, Xu, Wang, Yang, Xu, Qian, Chen: Construction of a genomic DNA library of the Toxoplasma gondii ZS2 strain, screening of specific clones, and DNA diagnosis of toxoplasmosis. in The American journal of tropical medicine and hygiene 1992 (PubMed)
    Show all 4 references for 2475490

  3. Human Polyclonal MAPKAP1 Primary Antibody for ICFC - ABIN2665262 : Schroder, Bushell, Sculley: The human stress-activated protein kinase-interacting 1 gene encodes JNK-binding proteins. in Cellular signalling 2005 (PubMed)
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更多抗MAPKAP1的相互作用对抗体

Fruit Fly (Drosophila melanogaster) Mitogen-Activated Protein Kinase Associated Protein 1 (MAPKAP1) interaction partners

  1. Sin1, Rictor, Trc and target of rapamycin (TOR), components of the TOR complex 2 (TORC2), are required for dendritic tiling of class IV da neurons

Human Mitogen-Activated Protein Kinase Associated Protein 1 (MAPKAP1) interaction partners

  1. SIN1 plays an important role in non-small cell lung cancer; SIN1 is a potential biomarker and a promising target in the treatment of NSCLC

  2. This study provides evidence that Sin1, a known element of the mammalian target of rapamycin (显示 FRAP1 抗体) complex 2 (mTORC2 (显示 CRTC2 抗体)), is required for Interferon-gamma (显示 IFNG 抗体)-induced phosphorylation and activation of AKT (显示 AKT1 抗体) and that such activation mediates downstream regulation of mTORC1 and its effectors.

  3. Intracellular localization of mTORC2 (显示 CRTC2 抗体) component, mSin1, contributes to regulation of Akt (显示 AKT1 抗体) phosphorylation.

  4. Akt (显示 AKT1 抗体) phosphorylates SIN1 at T86, enhancing mTORC2 (显示 CRTC2 抗体) kinase activity, which leads to phosphorylation of Akt (显示 AKT1 抗体) S473 by mTORC2 (显示 CRTC2 抗体), thereby catalyzing full activation of Akt (显示 AKT1 抗体).

  5. MAPKAP1 may represent a novel anti-infection and anti-fibrogenesis genomic locus in chronic schistosomiasis japonica.

  6. mitogen-activated protein kinase associated protein 1 rs10118570 may be an important protective factor for developing better management strategies in lung squamous cell carcinoma.

  7. DNA-PKcs (显示 PRKDC 抗体)-mTORC2 (显示 CRTC2 抗体)(SIN1) association is required for UVB-induced Akt (显示 AKT1 抗体) Ser (显示 SIGLEC1 抗体)-473 phosphorylation and cell survival.

  8. Estradiol and mTORC2 (显示 CRTC2 抗体) cooperate to enhance prostaglandin biosynthesis and tumorigenesis in TSC2 (显示 TSC2 抗体)-deficient lymphangioleiomyomatosis cells.

  9. results reveal a Sin1-phosphorylation-dependent mTORC2 (显示 CRTC2 抗体) regulation, providing a potential molecular mechanism by which mutations in the mTORC1-S6K (显示 RPS6KB1 抗体)-Sin1 signalling axis might cause aberrant hyper-activation of the mTORC2 (显示 CRTC2 抗体)-Akt (显示 AKT1 抗体) pathway

  10. NBS1 (显示 NBN 抗体) interacts with the mTOR (显示 FRAP1 抗体)/Rictor (显示 RICTOR 抗体)/SIN1 complex through the a.a. 221-402 domain and contributes to the activation of Akt (显示 AKT1 抗体) activity.

Mouse (Murine) Mitogen-Activated Protein Kinase Associated Protein 1 (MAPKAP1) interaction partners

  1. This study provides evidence that Sin1, a known element of the mammalian target of rapamycin (显示 FRAP1 抗体) complex 2 (mTORC2 (显示 CRTC2 抗体)), is required for Interferon-gamma (显示 IFNG 抗体)-induced phosphorylation and activation of AKT (显示 AKT1 抗体) and that such activation mediates downstream regulation of mTORC1 and its effectors.

  2. analysis of mTORC2 (显示 CRTC2 抗体) components mTOR (显示 FRAP1 抗体), Rictor (显示 RICTOR 抗体) and mSin1 reveals diurnal variation in mouse perivascular adipose tissue

  3. data suggest that DNA-PKcs (显示 PRKDC 抗体)-SIN1 complexation-mediated Akt (显示 AKT1 抗体) activation (Ser (显示 SIGLEC1 抗体)-473 phosphorylation) is required for mouse osteoblast differentiation

  4. these findings provide evidence for critical functions for Rictor (显示 RICTOR 抗体)/Sin1 complexes in type I IFN signaling and the generation of type I IFN antineoplastic responses.

  5. The phosphorylation of SIN1 by Akt (显示 AKT1 抗体) was found to regulate mTORC2 (显示 CRTC2 抗体) activity in response to growth factors, revealing topological insights into the Akt (显示 AKT1 抗体)/mTOR (显示 FRAP1 抗体) signaling network.

  6. Sin1 and mTORC2 (显示 CRTC2 抗体) are dispensable for the development and activation of T cells but play a role in nTreg-cell differentiation.

  7. mSIN1 protein mediates SGK1 (显示 SGK1 抗体) protein interaction with mTORC2 (显示 CRTC2 抗体) protein complex and is required for selective activation of the epithelial sodium channel

  8. MAP kinase (显示 MAPK1 抗体)-interacting kinase 1 and 2 activity enhances formation of the EIF-4F complex in pachytene spermatocytes but not in round spermatids.

  9. Sin1-mTORC2 (显示 CRTC2 抗体) suppresses rag1,2 and il7r (显示 IL7R 抗体) gene expression through Akt2 (显示 AKT2 抗体) in B cells.

  10. Results reveal that the SIN1-rictor (显示 RICTOR 抗体)-mTOR (显示 FRAP1 抗体) function in Akt (显示 AKT1 抗体)-Ser473 phosphorylation is required for TORC2 (显示 CRTC2 抗体) function in cell survival but is dispensable for TORC1 (显示 CRTC1 抗体) function.

MAPKAP1 抗原简介

Antigen Summary

This gene encodes a protein that is highly similar to the yeast SIN1 protein, a stress-activated protein kinase. Alternatively spliced transcript variants encoding distinct isoforms have been described. Alternate polyadenylation sites as well as alternate 3' UTRs have been identified for transcripts of this gene.

Alternative names and synonyms associated with MAPKAP1

  • SAPK-interacting protein 1 (Sin1) 抗体
  • mitogen-activated protein kinase associated protein 1 (MAPKAP1) 抗体
  • mitogen-activated protein kinase associated protein 1 (mapkap1) 抗体
  • mitogen-activated protein kinase associated protein 1 (Mapkap1) 抗体
  • AI591529 抗体
  • CG10105 抗体
  • D230039K05Rik 抗体
  • Dmel\\CG10105 抗体
  • dSin1 抗体
  • im:7143088 抗体
  • JC310 抗体
  • MAPKAP1 抗体
  • MGC53034 抗体
  • MIP1 抗体
  • si:ch73-242f23.1 抗体
  • Sin1 抗体
  • SIN1b 抗体
  • SIN1g 抗体

Protein level used designations for MAPKAP1

CG10105-PA , Sin1-PA , Stress-activated protein kinase [SAPK]-interacting protein , stress-activated map kinase-interacting protein 1 , mitogen-activated protein kinase associated protein 1 , Target of rapamycin complex 2 subunit MAPKAP1 , target of rapamycin complex 2 subunit MAPKAP1-like , MEKK2-interacting protein 1 , SAPK-interacting protein 1 , TORC2 subunit MAPKAP1 , mSIN1 , mitogen-activated protein kinase 2-associated protein 1 , ras inhibitor MGC2745 , stress-activated map kinase interacting protein 1 , stress-activated protein kinase-interacting 1 , target of rapamycin complex 2 subunit MAPKAP1 , mitogen activated protein kinase associated protein 1 , SAPK interacting protein

GENE ID SPECIES
36604 Drosophila melanogaster
464736 Pan troglodytes
480724 Canis lupus familiaris
492604 Danio rerio
100101680 Xenopus (Silurana) tropicalis
100390680 Callithrix jacchus
100481486 Ailuropoda melanoleuca
100601949 Nomascus leucogenys
79109 Homo sapiens
227743 Mus musculus
296648 Rattus norvegicus
533861 Bos taurus
395627 Gallus gallus
380158 Xenopus laevis
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