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抗Human Cyclin D1 抗体:
抗Mouse (Murine) Cyclin D1 抗体:
抗Rat (Rattus) Cyclin D1 抗体:
Human Monoclonal Cyclin D1 Primary Antibody for IHC (p) - ABIN1687223
Kunder, Calzada-Wack, Hölzlwimmer, Müller, Kloss, Howat, Schmidt, Höfler, Warren, Quintanilla-Martinez et al.: A comprehensive antibody panel for immunohistochemical analysis of formalin-fixed, paraffin-embedded hematopoietic neoplasms of mice: analysis of mouse specific and human antibodies cross-reactive ... in Toxicologic pathology 2007
Show all 172 Pubmed References
Human Monoclonal Cyclin D1 Primary Antibody for IHC (p), WB - ABIN1686967
Tsai, Morais, Alshalalfa, Tan, Haddad, Hicks, Gupta, Epstein, Netto, Isaacs, Luo, Mehra, Vessella, Karnes, Schaeffer, Davicioni, De Marzo, Lotan: Cyclin D1 Loss Distinguishes Prostatic Small-Cell Carcinoma from Most Prostatic Adenocarcinomas. in Clinical cancer research : an official journal of the American Association for Cancer Research 2015
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Human Polyclonal Cyclin D1 Primary Antibody for WB - ABIN3044355
Li, Xu, Chu, Gao, Wang, Nie, Yang, Lv: Molecular mechanism of inhibitory effects of CD59 gene on atherosclerosis in ApoE (-/-) mice. in Immunology letters 2013
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Human Monoclonal Cyclin D1 Primary Antibody for ICC, IHC (fro) - ABIN3043639
Ren, Huang, Xu, Yang, Yang, Hu: Isoflavone lupiwighteone induces cytotoxic, apoptotic, and antiangiogenic activities in DU-145 prostate cancer cells. in Anti-cancer drugs 2015
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Human Polyclonal Cyclin D1 Primary Antibody for WB - ABIN5518654
Li, Zhu, Liu, Liu, Wang, Xiong, Shen, Hu, Zheng: ZFX knockdown inhibits growth and migration of non-small cell lung carcinoma cell line H1299. in International journal of clinical and experimental pathology 2013
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Goat Polyclonal Cyclin D1 Primary Antibody for FACS, IF (cc) - ABIN671016
Li, Yu, Liu, Zhu, He, Peng, Hua: miR-34c works downstream of p53 leading to dairy goat male germline stem-cell (mGSCs) apoptosis. in Cell proliferation 2013
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Human Monoclonal Cyclin D1 Primary Antibody for FACS, IP - ABIN967430
Bates, Rowan, Vousden: Characterisation of human cyclin G1 and G2: DNA damage inducible genes. in Oncogene 1996
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Human Polyclonal Cyclin D1 Primary Antibody for WB - ABIN1881175
Aggarwal, Vaites, Kim, Mellert, Gurung, Nakagawa, Herlyn, Hua, Rustgi, McMahon, Diehl: Nuclear cyclin D1/CDK4 kinase regulates CUL4 expression and triggers neoplastic growth via activation of the PRMT5 methyltransferase. in Cancer cell 2010
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Human Monoclonal Cyclin D1 Primary Antibody for IHC (f), IHC (fro) - ABIN967539
Darzynkiewicz, Gong, Juan, Ardelt, Traganos: Cytometry of cyclin proteins. in Cytometry 1997
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Human Monoclonal Cyclin D1 Primary Antibody for ELISA, WB - ABIN969007
Parafioriti, del Bianco, Barisani, Armiraglio, Peretti, Albisetti: Increased p21 expression in chondrocytes of achondroplasic children independently from the presence of the G380R FGFR3 mutation. in Journal of orthopaedic science : official journal of the Japanese Orthopaedic Association 2009
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Results suggest that the TCF (显示 HNF4A 抗体)/LEF signaling pathway participates in the regulation of cyclin D1 induction during the generation of the dorsal nervous system in early frog embryogenesis.
while cyclin B1 RNA granules were disassembled in a manner dependent on actin filament depolymerization, certain fractions of mos RNA granules were disassembled independently of actin filaments. These results suggest that cytoplasmic regulation of translationally repressed mRNAs by formation of different RNA granules is a key mechanism for translational control of
Maid (显示 CCNDBP1 抗体) is important regulator of hepatocarcinogenesis and aging
show that the knockdown of smc1a (显示 SMC1A 抗体) in zebrafish impairs neural development, increases apoptosis, and specifically down-regulates Ccnd1 levels
Reduction of cyclin D1 expression compromises zebrafish eye and head development.
Role in cell cycle control is mediated by meis1 (显示 MEIS1 抗体) regulating cyclin D1 and c-myc (显示 MYC 抗体) transcription in the embryonic eye.
This meta-analysis suggests that the CCND1 G870A polymorphism is associated with an increased risk of colorectal cancer, especially that A carriers may be a major risk factor for colorectal cancer.
results showed that fascaplysin inhibited ovarian cancer cell proliferation, invasion and migration, as well as inducing S arrest and cell apoptosis. Treatment with fascaplysin also suppressed CDK4 (显示 CDK4 抗体), cyclin D1, Bcl-2 (显示 BCL2 抗体), and VEGFA (显示 VEGFA 抗体) expression at protein levels
Mutation in the CCND1 gene is associated with acute myeloid leukemia (显示 BCL11A 抗体).
The first preclinical study evaluates the response to CDK4/6 (显示 CDK4 抗体) inhibition in endometrial malignancies driven by PTEN (显示 PTEN 抗体) deficiency, and it reveals an important role of cyclin D-CDK4/6 (显示 CDK4 抗体) activity in their development.
High CCND1 expression is associated with oropharyngeal squamous cell carcinoma.
Describe a regulatory loop miR (显示 MLXIP 抗体)-218-CDK6 (显示 CDK6 抗体)/CyclinD1-E2F1 (显示 E2F1 抗体) whose disruption may contribute to cell cycle progression in gastric cancer.
EGF (显示 EGF 抗体) induces hair follicle-derived mesenchymal stem cell proliferation through the EGFR (显示 EGFR 抗体)/ERK (显示 EPHB2 抗体) and AKT (显示 AKT1 抗体) pathways, but not through STAT-3 (显示 STAT3 抗体). The G1/S transition was stimulated by upregulation of cyclinD1 and inhibition of p16 (显示 CDKN2A 抗体) expression.
Case Report: in the absence of the typical CCND1/IGH@ fusion, t(11;12)(q13;p11.2) promotes Mantle cell lymphoma pathogenesis by eliminating miRNA interaction elements within the 3'-UTR (显示 UTS2R 抗体) of the CCND1 mRNA transcript consequently resulting in CCND1 overexpression.
The CCND1 genes were found very close to the IGH locus in naive B cells and further away after maturation. In contrast, the CMYC (显示 MYC 抗体) alleles became localized closer to an IGH locus at the stage of SHM (显示 CNTNAP1 抗体)/CSR (显示 MORF4 抗体).
Consistently, samples from oral squamous cell carcinoma (OSCC) patients exhibited a noticeably stronger CREPT (显示 RPRD1B 抗体) expression than noncancerous samples. In contrast, knocking down of CREPT (显示 RPRD1B 抗体) in OSCC cell lines significantly reduced proliferation, colony formation and migration as well as the expression of cyclin D1 and c-Myc (显示 MYC 抗体), but promoted apoptosis.
NMB or NMBR (显示 NMBR 抗体) silencing inhibited M-CSF (显示 CSF1R 抗体)/c-Fms (显示 CSF1R 抗体)-mediated downstream signaling pathways like activation of ERK (显示 EPHB2 抗体) and Akt (显示 AKT1 抗体) and induction of D-type cyclins, cyclin D1 and D2.
Histone H2A T120 phosphorylation promotes oncogenic transformation via upregulation of cyclin D1.
our results are consistent with an epithelial proliferative growth mechanism linking CTNNB1 (显示 CTNNB1 抗体)-driven Ccnd1 transcription and estrogen-mediated CCND1 protein stabilization.
identify Pax5 (显示 PAX5 抗体) and cyclin D1 as Zfp521 (显示 ZNF521 抗体) target genes, and suggest that excessive B-cell proliferation observed in mice with retroviral insertions near the Zfp521 (显示 ZNF521 抗体) gene is due to an up-regulation of cyclin D1 in B-cells.
Data show that expression of the Oct-4 (显示 POU5F1 抗体), Sox2 (显示 SOX2 抗体), Klf4 (显示 KLF4 抗体), and c-Myc (显示 MYC 抗体) (OSKM) reprogramming factors induces Cyclin D1 expression, and the increased Cyclin D1 expression during reprogramming promotes continuing embryonic fibroblasts (MEFs) proliferation.
study shows that PLCgamma1 (显示 PLCG1 抗体) controls osteoclast numbers via a CSF-1 (显示 CSF1 抗体)-dependent DAG/beta-catenin (显示 CTNNB1 抗体)/cyclinD1 pathway.
Regarding extratelomeric activities, our results showed a decrease of 64, 38 and 25% in the transcription of c-Myc (显示 MYC 抗体), Cyc (显示 CYCS 抗体)-D1 and TERT (显示 TERT 抗体), respectively (p<0.05) after AZT treatment. Furthermore, we found an effect on cell migration, reaching an inhibition of 48% (p<0.05) and a significant passage-dependent increase on cell doubling time during treatment.
Using Ccnd1 knockout mice, the study shows that Ccnd1 expression significantly contributes to tumor incidence in teratoma (显示 DND1 抗体) susceptible mice without being necessary for normal germ cell or testis development.
Ras (G12V)-induced cyclin D1 protein synthesis was markedly suppressed by the knockdown of IL-33 (显示 IL33 抗体).
Novel RNA-binding activity of MYF5 (显示 MYF5 抗体) enhances Ccnd1 mRNA translation during myogenesis.
CCND1 mRNA expression is increased by FGF9 in bovine theca cells and granulosa cells.
cyclin D1, CDK2 (显示 CDK2 抗体) and CDK4 (显示 CDK4 抗体) are expressed in both caruncular and intercaruncular cells derived from both nonpregnant, and artificially inseminated cows on days 30 and 60 of gestation
17beta-estradiol (E2) induces cell proliferation of bovine arterial endothelial cells through upregulation of cyclin D1 via non-genomic activation of the extracellular signal-regulated microtubule-associated Protein 2 kinase (ERK1 (显示 MAPK3 抗体) kinase) pathway.
The protein encoded by this gene belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance throughout the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. This cyclin forms a complex with and functions as a regulatory subunit of CDK4 or CDK6, whose activity is required for cell cycle G1/S transition. This protein has been shown to interact with tumor suppressor protein Rb and the expression of this gene is regulated positively by Rb. Mutations, amplification and overexpression of this gene, which alters cell cycle progression, are observed frequently in a variety of tumors and may contribute to tumorigenesis.
G1/S-specific cyclin-D1 b
, cyclin D1 b
, parathyroid adenomatosis 1
, cyclin D1 (PRAD1: parathyroid adenomatosis 1)
, Cyclin-D1-binding protein 1 homolog
, cyclin Dx
, cyclin-D1-binding protein 1 homolog
, zebrafish homolog of Maid
, cyclin D1
, G1/S-specific cyclin-D1
, B-cell CLL/lymphoma 1
, B-cell lymphoma 1 protein
, BCL-1 oncogene
, PRAD1 oncogene
, G1/S-specific cyclin-D1 a
, cyclin D1 a (PRAD1: parathyroid adenomatosis 1)