anti-Cyclin D1 (CCND1) 抗体产品概述

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anti-Cyclin D1 抗体 (CCND1)
在www.antibodies-online.cn可供554 Cyclin D1 (CCND1) 抗体的35不同的供货商。 再加上,我们可以发Cyclin D1 试剂盒 (57)Cyclin D1 蛋白 (27)和数多这个蛋白质的别的产品。 总共665 Cyclin D1产品已列进来了。
AI327039, bcl-1, BCL1, cb161, CCND1, ccnd1a, ccnd1b, ccndbp1, cD1, cycd1, Cyl-1, D11S287E, etID37810.7, fb52e01, fc45c08, fc83a12, id:ibd1198, PRAD1, U21B31, wu:fb52e01, wu:fc45c08, wu:fc83a12, ZHM
列出全部抗体 基因 基因ID UniProt
CCND1 595 P24385
CCND1 12443 P25322
大鼠 CCND1 CCND1 58919 P39948



所有可销售的anti-Cyclin D1 抗体


引用最多的anti-Cyclin D1 抗体

  1. Human Monoclonal Cyclin D1 Primary Antibody for IHC (p) - ABIN1687223 : Kunder, Calzada-Wack, Hölzlwimmer, Müller, Kloss, Howat, Schmidt, Höfler, Warren, Quintanilla-Martinez et al.: A comprehensive antibody panel for immunohistochemical analysis of formalin-fixed, paraffin-embedded hematopoietic neoplasms of mice: analysis of mouse specific and human antibodies cross-reactive ... in Toxicologic pathology 2007 (PubMed)
    Show all 172 references for 1687223

  2. Human Polyclonal Cyclin D1 Primary Antibody for IF, IHC (p) - ABIN389146 : He, Council, Feng, Chignell: UVA-induced cell cycle progression is mediated by a disintegrin and metalloprotease/epidermal growth factor receptor/AKT/Cyclin D1 pathways in keratinocytes. in Cancer research 2008 (PubMed)
    Show all 3 references for 389146

  3. Human Monoclonal Cyclin D1 Primary Antibody for IHC (fro), IF - ABIN1106872 : Rosenberg, Kim, Shows, Kronenberg, Arnold: Rearrangement and overexpression of D11S287E, a candidate oncogene on chromosome 11q13 in benign parathyroid tumors. in Oncogene 1991 (PubMed)
    Show all 3 references for 1106872

  4. Human Monoclonal Cyclin D1 Primary Antibody for FACS, IHC (p) - ABIN1106871 : Zou, Peng, Zhou, Wen, Wang, Tsai, Hung: Systemic tumor suppression by the proapoptotic gene bik. in Cancer research 2002 (PubMed)
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  5. Human Polyclonal Cyclin D1 Primary Antibody for WB - ABIN389144 : Marsit, Black, Posner, Kelsey: A genotype-phenotype examination of cyclin D1 on risk and outcome of squamous cell carcinoma of the head and neck. in Clinical cancer research : an official journal of the American Association for Cancer Research 2008 (PubMed)
    Show all 3 references for 389144

  6. Human Polyclonal Cyclin D1 Primary Antibody for IF, WB - ABIN651507 : Edel, Menchon, Menendez, Consiglio, Raya, Izpisua Belmonte: Rem2 GTPase maintains survival of human embryonic stem cells as well as enhancing reprogramming by regulating p53 and cyclin D1. in Genes & development 2010 (PubMed)
    Show all 2 references for 651507

  7. Cow (Bovine) Polyclonal Cyclin D1 Primary Antibody for IHC, WB - ABIN2777893 : Kibel, Jin, Klim, Luly, A Roehl, Wu, Suarez: Association between polymorphisms in cell cycle genes and advanced prostate carcinoma. in The Prostate 2008 (PubMed)

更多抗Cyclin D1的相互作用对抗体

Xenopus laevis Cyclin D1 (CCND1) interaction partners

  1. Results suggest that the TCF (显示 HNF4A 抗体)/LEF signaling pathway participates in the regulation of cyclin D1 induction during the generation of the dorsal nervous system in early frog embryogenesis.

Zebrafish Cyclin D1 (CCND1) interaction partners

  1. while cyclin B1 RNA granules were disassembled in a manner dependent on actin filament depolymerization, certain fractions of mos RNA granules were disassembled independently of actin filaments. These results suggest that cytoplasmic regulation of translationally repressed mRNAs by formation of different RNA granules is a key mechanism for translational control of

  2. Maid (显示 CCNDBP1 抗体) is important regulator of hepatocarcinogenesis and aging

  3. show that the knockdown of smc1a (显示 SMC1A 抗体) in zebrafish impairs neural development, increases apoptosis, and specifically down-regulates Ccnd1 levels

  4. Reduction of cyclin D1 expression compromises zebrafish eye and head development.

  5. Role in cell cycle control is mediated by meis1 (显示 MEIS1 抗体) regulating cyclin D1 and c-myc (显示 MYC 抗体) transcription in the embryonic eye.

Human Cyclin D1 (CCND1) interaction partners

  1. EGF (显示 EGF 抗体) induces hair follicle-derived mesenchymal stem cell proliferation through the EGFR (显示 EGFR 抗体)/ERK (显示 EPHB2 抗体) and AKT (显示 AKT1 抗体) pathways, but not through STAT-3 (显示 STAT3 抗体). The G1/S transition was stimulated by upregulation of cyclinD1 and inhibition of p16 (显示 CDKN2A 抗体) expression.

  2. Case Report: in the absence of the typical CCND1/IGH@ fusion, t(11;12)(q13;p11.2) promotes Mantle cell lymphoma pathogenesis by eliminating miRNA interaction elements within the 3'-UTR (显示 UTS2R 抗体) of the CCND1 mRNA transcript consequently resulting in CCND1 overexpression.

  3. The CCND1 genes were found very close to the IGH locus in naive B cells and further away after maturation. In contrast, the CMYC (显示 MYC 抗体) alleles became localized closer to an IGH locus at the stage of SHM (显示 CNTNAP1 抗体)/CSR (显示 MORF4 抗体).

  4. Consistently, samples from oral squamous cell carcinoma (OSCC) patients exhibited a noticeably stronger CREPT (显示 RPRD1B 抗体) expression than noncancerous samples. In contrast, knocking down of CREPT (显示 RPRD1B 抗体) in OSCC cell lines significantly reduced proliferation, colony formation and migration as well as the expression of cyclin D1 and c-Myc (显示 MYC 抗体), but promoted apoptosis.

  5. Histone H2A T120 phosphorylation promotes oncogenic transformation via upregulation of cyclin D1.

  6. cyclin D1 and other cyclins such as cyclin A (显示 CCNA2 抗体) regulates DNA integrity through RAD51 (显示 RAD51 抗体) interaction with the BRCA2 (显示 BRCA2 抗体) C-terminal domain

  7. gankyrin (显示 PSMD10 抗体) regulates HIF-1alpha (显示 HIF1A 抗体) protein stability and cyclin D1 expression, ultimately mediating FSH (显示 BRD2 抗体)-driven ovarian cancer cell proliferation

  8. Cyclin D1 can be exploitable as a diagnostic adjunct to conventional markers in confirming the diagnosis of Esing sarcoma/peripheral primitive neuroectodermal tumors or neuroblastoma (显示 ARHGEF16 抗体)/ganglioneuroblastoma.

  9. ZNF322A (显示 ZNF322A 抗体) overexpression transcriptionally dysregulates genes involved in cell growth and motility therefore contributes to lung tumorigenesis and poor prognosis

  10. Amplification of the G1-S regulatory genes, CCNE1, CCND1 and CdK6, represent an early event, which precedes ERBB2, EGFR, or KRAS amplification in gastric adenocarcinoma.

Mouse (Murine) Cyclin D1 (CCND1) interaction partners

  1. Histone H2A T120 phosphorylation promotes oncogenic transformation via upregulation of cyclin D1.

  2. our results are consistent with an epithelial proliferative growth mechanism linking CTNNB1 (显示 CTNNB1 抗体)-driven Ccnd1 transcription and estrogen-mediated CCND1 protein stabilization.

  3. identify Pax5 (显示 PAX5 抗体) and cyclin D1 as Zfp521 (显示 ZNF521 抗体) target genes, and suggest that excessive B-cell proliferation observed in mice with retroviral insertions near the Zfp521 (显示 ZNF521 抗体) gene is due to an up-regulation of cyclin D1 in B-cells.

  4. Data show that expression of the Oct-4 (显示 POU5F1 抗体), Sox2 (显示 SOX2 抗体), Klf4 (显示 KLF4 抗体), and c-Myc (显示 MYC 抗体) (OSKM) reprogramming factors induces Cyclin D1 expression, and the increased Cyclin D1 expression during reprogramming promotes continuing embryonic fibroblasts (MEFs) proliferation.

  5. study shows that PLCgamma1 (显示 PLCG1 抗体) controls osteoclast numbers via a CSF-1 (显示 CSF1 抗体)-dependent DAG/beta-catenin (显示 CTNNB1 抗体)/cyclinD1 pathway.

  6. Regarding extratelomeric activities, our results showed a decrease of 64, 38 and 25% in the transcription of c-Myc (显示 MYC 抗体), Cyc (显示 CYCS 抗体)-D1 and TERT (显示 TERT 抗体), respectively (p<0.05) after AZT treatment. Furthermore, we found an effect on cell migration, reaching an inhibition of 48% (p<0.05) and a significant passage-dependent increase on cell doubling time during treatment.

  7. Using Ccnd1 knockout mice, the study shows that Ccnd1 expression significantly contributes to tumor incidence in teratoma (显示 DND1 抗体) susceptible mice without being necessary for normal germ cell or testis development.

  8. Ras (G12V)-induced cyclin D1 protein synthesis was markedly suppressed by the knockdown of IL-33 (显示 IL33 抗体).

  9. Novel RNA-binding activity of MYF5 (显示 MYF5 抗体) enhances Ccnd1 mRNA translation during myogenesis.

  10. The robust increase in the expression of cyclin D1 and CDK4 (显示 CDK4 抗体) at day 2 suggests that Muller glia may be in G1 phase of the cell cycle at this stage.

Cow (Bovine) Cyclin D1 (CCND1) interaction partners

  1. cyclin D1, CDK2 (显示 CDK2 抗体) and CDK4 (显示 CDK4 抗体) are expressed in both caruncular and intercaruncular cells derived from both nonpregnant, and artificially inseminated cows on days 30 and 60 of gestation

  2. 17beta-estradiol (E2) induces cell proliferation of bovine arterial endothelial cells through upregulation of cyclin D1 via non-genomic activation of the extracellular signal-regulated microtubule-associated Protein 2 kinase (ERK1 (显示 MAPK3 抗体) kinase) pathway.

Cyclin D1 (CCND1) 抗原简介

Antigen Summary

The protein encoded by this gene belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance throughout the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. This cyclin forms a complex with and functions as a regulatory subunit of CDK4 or CDK6, whose activity is required for cell cycle G1/S transition. This protein has been shown to interact with tumor suppressor protein Rb and the expression of this gene is regulated positively by Rb. Mutations, amplification and overexpression of this gene, which alters cell cycle progression, are observed frequently in a variety of tumors and may contribute to tumorigenesis.

Alternative names and synonyms associated with Cyclin D1 (CCND1)

  • cyclin D1 (ccnd1-b) 抗体
  • cyclin D1 (ccnd1) 抗体
  • Cyclin-D1-binding protein 1 homolog (ccndbp1) 抗体
  • cyclin Dx (ccndx) 抗体
  • zgc:162082 (zgc:162082) 抗体
  • cyclin D1 (CCND1) 抗体
  • G1/S-specific cyclin-D1 (ccnd1) 抗体
  • cyclin D1 (Ccnd1) 抗体
  • cyclin D1 (ccnd1-a) 抗体
  • AI327039 抗体
  • bcl-1 抗体
  • BCL1 抗体
  • cb161 抗体
  • CCND1 抗体
  • ccnd1a 抗体
  • ccnd1b 抗体
  • ccndbp1 抗体
  • cD1 抗体
  • cycd1 抗体
  • Cyl-1 抗体
  • D11S287E 抗体
  • etID37810.7 抗体
  • fb52e01 抗体
  • fc45c08 抗体
  • fc83a12 抗体
  • id:ibd1198 抗体
  • PRAD1 抗体
  • U21B31 抗体
  • wu:fb52e01 抗体
  • wu:fc45c08 抗体
  • wu:fc83a12 抗体
  • ZHM 抗体

Protein level used designations for anti-Cyclin D1 (CCND1) 抗体

G1/S-specific cyclin-D1 b , cyclin D1 b , parathyroid adenomatosis 1 , cyclin D1 (PRAD1: parathyroid adenomatosis 1) , Cyclin-D1-binding protein 1 homolog , cyclin Dx , cyclin-D1-binding protein 1 homolog , zebrafish homolog of Maid , cyclin D1 , G1/S-specific cyclin-D1 , B-cell CLL/lymphoma 1 , B-cell lymphoma 1 protein , BCL-1 oncogene , PRAD1 oncogene , G1/S-specific cyclin-D1 a , cyclin D1 a (PRAD1: parathyroid adenomatosis 1)

379161 Xenopus laevis
448045 Xenopus (Silurana) tropicalis
495493 Xenopus laevis
548862 Xenopus (Silurana) tropicalis
553373 Danio rerio
574320 Macaca mulatta
747688 Pan troglodytes
100037407 Felis catus
100306852 Salmo salar
595 Homo sapiens
449028 Canis lupus familiaris
100009036 Oryctolagus cuniculus
12443 Mus musculus
58919 Rattus norvegicus
100729808 Cavia porcellus
100171625 Pongo abelii
379937 Xenopus laevis
396341 Gallus gallus
524530 Bos taurus
30222 Danio rerio
100144763 Ovis aries
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