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Wingless-Type MMTV Integration Site Family, Member 3 (WNT3) (Middle Region) Peptide

WNT3 适用: 人 宿主: 合成 BP, WB
产品编号 ABIN986218
发货至: 中国
  • 抗原 See all WNT3 products
    WNT3 (Wingless-Type MMTV Integration Site Family, Member 3 (WNT3))
    蛋白结构域
    Middle Region
    宿主
    资源
    • 3
    合成
    应用范围
    Blocking Peptide (BP), Western Blotting (WB)
    序列
    SHHKGPPGEG WKWGGCSEDA DFGVLVSREF ADARENRPDA RSAMNKHNNE
    产品特性
    This is a synthetic peptide designed for use in combination with anti-WNT3 Antibody(ARP49956_P050),. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
    纯化方法
    Purified
  • 应用备注
    Each Investigator should determine their own optimal working dilution for specific applications.
    限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
    浓度
    1 mg/mL
    缓冲液
    Final peptide concentration is 1 mg/mL in PBS.
    注意事项
    Avoid repeated freeze-thaw cycles.
    储存条件
    -20 °C
    储存方法
    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • 抗原
    WNT3 (Wingless-Type MMTV Integration Site Family, Member 3 (WNT3))
    别名
    INT4 Peptide, Ci-Wnt3 Peptide, WNT3 Peptide, int4 Peptide, Xwnt3 Peptide, wnt-3 Peptide, wnt3l Peptide, Xwnt-3 Peptide, wnt3 Peptide, Int-4 Peptide, Wnt-3 Peptide, wnt3-A Peptide, Wnt family member 3 Peptide, wingless-type MMTV integration site family, member 3 Peptide, proto-oncogene Wnt-3 Peptide, wingless-type MMTV integration site family member 3 Peptide, Wnt family member 3A Peptide, wingless-type MMTV integration site family member 3 L homeolog Peptide, WNT3 Peptide, Wnt3 Peptide, wnt3 Peptide, LOC468297 Peptide, WNT3A Peptide, wnt3.L Peptide
    背景
    The WNT gene family consists of structurally related genes which encode secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. This gene is a member of the WNT gene family. It encodes a protein which shows 98 % amino acid identity to mouse Wnt3 protein, and 84 % to human WNT3A protein, another WNT gene product. The mouse studies show the requirement of Wnt3 in primary axis formation in the mouse. Studies of the gene expression suggest that this gene may play a key role in some cases of human breast, rectal, lung, and gastric cancer through activation of the WNT-beta-catenin-TCF signaling pathway. This gene is clustered with WNT15, another family member, in the chromosome 17q21 region.

    Alias Symbols: INT4, MGC131950, MGC138321, MGC138323

    Protein Interaction Partner: FZD1

    Protein Size: 355
    分子量
    37 kDa
    基因ID
    7473
    NCBI登录号
    NM_030753, NP_110380
    UniProt
    P56703
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